Search Results - "Beemon, K L"

Rous Sarcoma Virus DR Posttranscriptional Elements Use a Novel RNA Export Pathway by Paca, R E, Ogert, R A, Hibbert, C S, Izaurralde, E, Beemon, K L

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Avian retroviral RNA element promotes unspliced RNA accumulation in the cytoplasm by Ogert, R A, Lee, L H, Beemon, K L

“…All retroviruses need mechanisms for nucleocytoplasmic export of their unspliced RNA and for maintenance of this RNA in the cytoplasm, where it is either…”
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Retroviral Splicing Suppressor Requires Three Nonconsensus Uridines in a 5′ Splice Site-Like Sequence by Paca, R E, Hibbert, C S, O'Sullivan, C T, Beemon, K L

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BK virus T antigens induce kidney carcinomas and thymoproliferative disorders in transgenic mice by DALRYMPLE, S. A, BEEMON, K. L

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Minimal truncation of the c-myb gene product in rapid-onset B-cell lymphoma by Jiang, W, Kanter, M R, Dunkel, I, Ramsay, R G, Beemon, K L, Hayward, W S

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Genetic determinant of rapid-onset B-cell lymphoma by avian leukosis virus by Smith, M.R. (Fox Chase Cancer Center, Philadelphia, PA.), Smith, R.E, Dunkel, I, Hou, V, Beemon, K.L, Hayward, W.S

“…Infection of 10 day-old chicken embryos with the recombinant avian leukosis virus (ALV) EU-8 induces a high incidence of rapid-onset B-cell lymphoma by…”
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A nonsense mutation in the fibrillin-1 gene of a Marfan syndrome patient induces NMD and disrupts an exonic splicing enhancer by Caputi, Massimo, Kendzior, Jr, Raymond J, Beemon, Karen L

“…A nonsense mutation in the fibrillin-1 (FBN1) gene of a Marfan syndrome (MFS) patient induces in-frame exon skipping of FBN1 exon 51. We present evidence,…”
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Unspliced Rous Sarcoma Virus Genomic RNAs Are Translated and Subjected to Nonsense-Mediated mRNA Decay before Packaging by LEBLANC, Jason J, BEEMON, Karen L

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Packaging and reverse transcription of snRNAs by retroviruses may generate pseudogenes by Giles, Keith E, Caputi, Massimo, Beemon, Karen L

“…Retroviruses specifically package two copies of their RNA genome in each viral particle, along with some small cellular RNAs, including tRNAs and 7S L RNA. We…”
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Functional genomic analysis reveals distinct neoplastic phenotypes associated with c-myb mutation in the bursa of Fabricius by NEIMAN, Paul E, GRBIC, Jovana J, POLONY, Tatjana S, KIMMEL, Robert, BOWERS, Sandra J, DELROW, Jeffrey, BEEMON, Karen L

“…Avian retroviral integration into the c-myb locus is casually associated with the development of lymphomas in the bursa of Farbricius of chickens; these arise…”
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Silent Point Mutation in an Avian Retrovirus RNA Processing Element Promotes c-myb-Associated Short-Latency Lymphomas by Polony, Tatjana S, Bowers, Sandra J, Neiman, Paul E, Beemon, Karen L

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Rous Sarcoma Virus Negative Regulator of Splicing Selectively Suppresses src mRNA Splicing and Promotes Polyadenylation by O'Sullivan, Christopher T., Polony, Tatjana S., Paca, Robert E., Beemon, Karen L.

“…Retroviruses require a balance of spliced and unspliced RNA for efficient replication. Here, we examined the effect of mutations in a splicing suppressor…”
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The role of overlapping U1 and U11 5′ splice site sequences in a negative regulator of splicing by HIBBERT, CATHERINE S., GONTAREK, RICHARD R., BEEMON, KAREN L.

“…Splicing of Rous sarcoma virus RNA is regulated in part by a cis-acting intronic RNA element called the negative regulator of splicing (NRS). An NRS mutant…”
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Genomic complexities of murine leukemia and sarcoma, reticuloendotheliosis, and visna viruses by Beemon, K L, Faras, A J, Hasse, A T, Duesberg, P H, Maisel, J E

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Mutational analysis of the Rous sarcoma virus DR posttranscriptional control element by Ogert, R.A, Beemon, K.L

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Rapid induction of B-cell lymphomas by avian leukosis virus by BEEMON, K. L, O'REILLY, M. M, SMITH, M. R, SMITH, R. E, DUNKEL, I, HAYWARD, W. S

“…Avian leukosis viruses (ALVs) that induce rapid B-cell lymphomas integrate into the c-myb gene and produce an ALV-myb read-through RNA, which is spliced to…”
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Tap and Dbp5, but not Gag, are involved in DR-mediated nuclear export of unspliced Rous sarcoma virus RNA by LeBlanc, Jason J, Uddowla, Sabena, Abraham, Benjamin, Clatterbuck, Sarah, Beemon, Karen L

“…Abstract All retroviruses must circumvent cellular restrictions on the export of unspliced RNAs from the nucleus. While the unspliced RNA export pathways for…”
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Oligonucleotide fingerprinting with RNA tumor virus RNA by Beemon, K L

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RNA Regulatory Elements in the Genomes of Simple Retroviruses by Banks, Jennifer D., Beemon, Karen L., Linial, Maxine L.

“…The RNA genomes of simple retroviruses encode three genes (gag, pol,andenv) which are required for replication. In addition, there are at least three…”
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A 3' UTR sequence stabilizes termination codons in the unspliced RNA of Rous sarcoma virus by Weil, Jason E, Beemon, Karen L

“…Eukaryotic cells target mRNAs to the nonsense-mediated mRNA decay (NMD) pathway when translation terminates within the coding region. In mammalian cells, this…”
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