Search Results - "Beekers, Ines"

Opening of endothelial cell–cell contacts due to sonoporation by Beekers, Inés, Vegter, Merel, Lattwein, Kirby R., Mastik, Frits, Beurskens, Robert, van der Steen, Antonius F.W., de Jong, Nico, Verweij, Martin D., Kooiman, Klazina

“…Ultrasound insonification of microbubbles can locally increase vascular permeability to enhance drug delivery. To control and optimize the therapeutic…”
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Ligand Distribution and Lipid Phase Behavior in Phospholipid-Coated Microbubbles and Monolayers by Langeveld, Simone A. G, Schwieger, Christian, Beekers, Inés, Blaffert, Jacob, van Rooij, Tom, Blume, Alfred, Kooiman, Klazina

“…Phospholipid-coated targeted microbubbles are ultrasound contrast agents that can be used for molecular imaging and enhanced drug delivery. However, a better…”
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Viability of endothelial cells after ultrasound-mediated sonoporation: Influence of targeting, oscillation, and displacement of microbubbles by van Rooij, Tom, Skachkov, Ilya, Beekers, Inés, Lattwein, Kirby R., Voorneveld, Jason D., Kokhuis, Tom J.A., Bera, Deep, Luan, Ying, van der Steen, Antonius F.W., de Jong, Nico, Kooiman, Klazina

“…Microbubbles (MBs) have been shown to create transient or lethal pores in cell membranes under the influence of ultrasound, known as ultrasound-mediated…”
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High-Resolution Imaging of Intracellular Calcium Fluctuations Caused by Oscillating Microbubbles by Beekers, Inés, Mastik, Frits, Beurskens, Robert, Tang, Phoei Ying, Vegter, Merel, van der Steen, Antonius F.W., de Jong, Nico, Verweij, Martin D., Kooiman, Klazina

“…Ultrasound insonification of microbubbles can locally enhance drug delivery, but the microbubble–cell interaction remains poorly understood. Because…”
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Internalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnels by Beekers, Inés, Langeveld, Simone A.G., Meijlink, Bram, van der Steen, Antonius F.W., de Jong, Nico, Verweij, Martin D., Kooiman, Klazina

“…Ultrasound insonification of microbubbles can locally enhance drug delivery by increasing the cell membrane permeability. To aid development of a safe and…”
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Ultrasonic Characterization of Ibidi μ-Slide I Luer Channel Slides for Studies With Ultrasound Contrast Agents by Pakdaman Zangabad, Reza, Li, Hongchen, Kouijzer, Joop J. P., Langeveld, Simone A. G., Beekers, Ines, Verweij, Martin, De Jong, Nico, Kooiman, Klazina

“…Understanding and controlling the ultrasound contrast agent (UCA)'s response to an applied ultrasound pressure field are crucial when investigating ultrasound…”
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Vancomycin-decorated microbubbles as a theranostic agent for Staphylococcus aureus biofilms by Kouijzer, Joop J.P., Lattwein, Kirby R., Beekers, Inés, Langeveld, Simone A.G., Leon-Grooters, Mariël, Strub, Jean-Marc, Oliva, Estefania, Mislin, Gaëtan L.A., de Jong, Nico, van der Steen, Antonius F.W., Klibanov, Alexander L., van Wamel, Willem J.B., Kooiman, Klazina

“…[Display omitted] Bacterial biofilms are a huge burden on our healthcare systems worldwide. The lack of specificity in diagnostic and treatment possibilities…”
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Whole blood transcriptome in long-COVID patients reveals association with lung function and immune response by Blankestijn, Jelle M., Baalbaki, Nadia, Bazdar, Somayeh, Beekers, Inés, Beijers, Rosanne J.H.C.G., van den Bergh, Joop P., Bloemsma, Lizan D., Cornelissen, Merel E.B., Dekker, Tamara, Duitman, Jan Willem, Houweling, Laura, Jacobs, John J.L., van der Lee, Ivo, Linders, Paulien M.A., Noij, Lieke C.E., Nossent, Esther J., van de Pol, Marianne A., Sondermeijer, Brigitte M., Geelhoed, J.J. Miranda, Weersink, Els J.M., Golebski, Korneliusz, Abdel-Aziz, Mahmoud I., Maitland-van der Zee, Anke H.

“…[Display omitted] Months after infection with severe acute respiratory syndrome coronavirus 2, at least 10% of patients still experience complaints. Long-COVID…”
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Combined Confocal Microscope and Brandaris 128 Ultra-High-Speed Camera by Beekers, Inés, Lattwein, Kirby R., Kouijzer, Joop J.P., Langeveld, Simone A.G., Vegter, Merel, Beurskens, Robert, Mastik, Frits, Verduyn Lunel, Rogier, Verver, Emma, van der Steen, Antonius F.W., de Jong, Nico, Kooiman, Klazina

“…Controlling microbubble-mediated drug delivery requires the underlying biological and physical mechanisms to be unraveled. To image both microbubble…”
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The Impact of Lipid Handling and Phase Distribution on the Acoustic Behavior of Microbubbles by Langeveld, Simone A G, Beekers, Inés, Collado-Lara, Gonzalo, van der Steen, Antonius F W, de Jong, Nico, Kooiman, Klazina

“…Phospholipid-coated microbubbles are ultrasound contrast agents that can be employed for ultrasound molecular imaging and drug delivery. For safe and effective…”
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Theranostic Microbubbles with Homogeneous Ligand Distribution for Higher Binding Efficacy by Langeveld, Simone A G, Meijlink, Bram, Beekers, Inés, Olthof, Mark, van der Steen, Antonius F W, de Jong, Nico, Kooiman, Klazina

“…Phospholipid-coated targeted microbubbles are used for ultrasound molecular imaging and locally enhanced drug delivery, with the binding efficacy being an…”
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Dispersing and Sonoporating Biofilm-Associated Bacteria with Sonobactericide by Lattwein, Kirby R, Beekers, Inés, Kouijzer, Joop J P, Leon-Grooters, Mariël, Langeveld, Simone A G, van Rooij, Tom, van der Steen, Antonius F W, de Jong, Nico, van Wamel, Willem J B, Kooiman, Klazina

“…Bacteria encased in a biofilm poses significant challenges to successful treatment, since both the immune system and antibiotics are ineffective…”
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Long COVID exhibits clinically distinct phenotypes at 3–6 months post-SARS-CoV-2 infection: results from the P4O2 consortium by Blankestijn, Jelle M, Abdel-Aziz, Mahmoud I, Baalbaki, Nadia, Bazdar, Somayeh, Beekers, Inés, Beijers, Rosanne J H C G, Bloemsma, Lizan D, Cornelissen, Merel E B, Gach, Debbie, Houweling, Laura, Holverda, Sebastiaan, Jacobs, John J L, Jonker, Reneé, van der Lee, Ivo, Linders, Paulien M A, Mohamed Hoesein, Firdaus A A, Noij, Lieke C E, Nossent, Esther J, van de Pol, Marianne A, Schaminee, Daphne W, Schols, Annemie M W J, Schuurman, Lisanne T, Sondermeijer, Brigitte, Geelhoed, J J Miranda, van den Bergh, Joop P, Weersink, Els J M, de Wit-van Wijck, Yolanda, Maitland-van der Zee, Anke H

“…BackgroundFour months after SARS-CoV-2 infection, 22%–50% of COVID-19 patients still experience complaints. Long COVID is a heterogeneous disease and finding…”
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The spatial distribution of the ligand on targeted microbubbles influences the binding efficacy by Langeveld, Simone A. G., Meijlink, Bram, Beekers, Ines, Olthof, Mark, van der Steen, Antonius F., de Jong, Nico, Kooiman, Klazina

“…An important trait of targeted microbubbles is their binding to biomarkers for ultrasound molecular imaging and drug delivery. Using organic solvents in…”
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The OrganoPlate® as vessel-on-a-chip model to investigate increased microbubble-mediated vascular permeability by Meijlink, Bram, Beekers, Ines, Langeveld, Simone A. G., Bishard, Kristina, van der Steen, Antonius F., de Jong, Nico, Trietsch, Sebastiaan J., Kooiman, Klazina

“…The vessel wall is an important barrier modulating drug delivery to the underlying diseased tissue. Oscillating microbubbles can be used to locally enhance…”
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Microbubble-endothelial cell interactions in 3D: Internalization of microbubbles and pore or tunnel formation for drug delivery by Beekers, Ines, Langeveld, Simone A. G., Meijlink, Bram, van der Steen, Antonius F., de Jong, Nico, Verweij, Martin D., Kooiman, Klazina

“…Ultrasound-activated microbubbles can locally enhance vascular drug delivery, but fully understanding the mechanism requires further investigation. The aims of…”
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Phospholipid-coated microbubbles: Controlling response to ultrasound by Langeveld, Simone A., Beekers, Ines, van der Steen, Antonius F. W., de Jong, Nico, Kooiman, Klazina

“…Variability in response to ultrasound is an issue when microbubbles are used for drug delivery. This may be caused by immiscible phospholipid components and…”
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Acoustic Characterization of a Vessel-on-a-Chip Microfluidic System for Ultrasound-Mediated Drug Delivery by Beekers, Ines, van Rooij, Tom, Verweij, Martin D., Versluis, Michel, de Jong, Nico, Trietsch, Sebastiaan J., Kooiman, Klazina

“…Ultrasound in the presence of gas-filled microbubbles can be used to enhance local uptake of drugs and genes. To study the drug delivery potential and its…”
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Corrections to "Vibrational Responses of Bound and Nonbound Targeted Lipid-Coated Single Microbubbles" by Rooij, Tom van, Beekers, Ines, Lattwein, Kirby R., van der Steen, Antonius F. W., de Jong, Nico, Kooiman, Klazina

“…In the above article <xref ref-type="bibr" rid="ref1">[1] , the authors regret that there was a mistake in calculating the mol% of the microbubble coating…”
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Acoustic Characterization of the CLINIcell for Ultrasound Contrast Agent Studies by Beekers, Ines, van Rooij, Tom, van der Steen, Antonius F. W., de Jong, Nico, Verweij, Martin D., Kooiman, Klazina

“…Ultrasound contrast agents consist of gas-filled coated microbubbles that oscillate upon ultrasound insonification. Their characteristic oscillatory response…”
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