Search Results - "Beeh, K M"

Benefits of omalizumab as add‐on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE by Humbert, M., Beasley, R., Ayres, J., Slavin, R., Hébert, J., Bousquet, J., Beeh, K.‐M., Ramos, S., Canonica, G. W., Hedgecock, S., Fox, H., Blogg, M., Surrey, K.

“…Background:  Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 therapy are a…”
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Bronchodilator effects of indacaterol and formoterol in patients with COPD by Beier, J, Beeh, K.-M, Brookman, L, Peachey, G, Hmissi, A, Pascoe, S

“…Abstract Background Resting inspiratory capacity (IC) reflects static hyperinflation in chronic obstructive pulmonary disease (COPD). This study compared the…”
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Randomised controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma by Price, D B, Hernandez, D, Magyar, P, Fiterman, J, Beeh, K M, James, I G, Konstantopoulos, S, Rojas, R, van Noord, J A, Pons, M, Gilles, L, Leff, J A

“…Background: Inhaled corticosteroids (ICS) affect many inflammatory pathways in asthma but have little impact on cysteinyl leukotrienes. This may partly explain…”
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Sputum matrix metalloproteinase-9, tissue inhibitor of metalloprotinease-1, and their molar ratio in patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and healthy subjects by BEEH, K.M., BEIER, J., KORNMANN, O., BUHL, R.

“…Background: Matrix-metalloproteinases (MMPs) and their inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), are involved in the turnover of…”
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Elevation of total serum immunoglobulin E is associated with asthma in nonallergic individuals by Beeh, KM, Ksoll, M, Buhl, R

“…Elevated serum immunoglobulin (Ig)E is the hallmark of atopy, and contributes to asthma and bronchial hyperresponsiveness in atopic individuals. In contrast,…”
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Handle with care: targeting neutrophils in chronic obstructive pulmonary disease and severe asthma? by Beeh, K. M., Beier, J.

“…Summary Neutrophils play an important role in the pathogenesis of airway inflammation in both chronic obstructive pulmonary disease (COPD) and severe asthma…”
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Glutathione deficiency of the lower respiratory tract in patients with idiopathic pulmonary fibrosis by Beeh, K.M, Beier, J, Haas, I.C, Kornmann, O, Micke, P, Buhl, R

“…Idiopathic pulmonary fibrosis (IPF) is a disease of unknown aetiology. Increased oxidant burden and antioxidant, e.g. glutathione (GSH), deficiency in the…”
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A single nasal allergen challenge increases induced sputum inflammatory markers in non-asthmatic subjects with seasonal allergic rhinitis: correlation with plasma interleukin-5 by Beeh, K. M., Beier, J., Kornmann, O., Meier, C., Taeumer, T., Buhl, R.

“…Summary Background Seasonal allergic rhinitis (SAR) is a risk factor for asthma in affected individuals. Nasal allergic inflammation enhances bone‐marrow…”
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The concept of chronic obstructive pulmonary disease clinical control as a decision - making tool in real clinical practice for optimizing of basic pharmacotherapy by Avdeev, S N, Aisanov, Z R, Belevsky, A S, Beeh, K M, Vizel, A A, Zyryanov, S K, Ignatova, G L, Kostikas, K, Leshchenko, I V, Ovcharenko, S I, Sinopal’nikov, A I, Titova, O N, Shmelev, E I

“…The main goals of COPD therapy are to achieve clinical stability with minimal clinical manifestations and low risk of relapse. The proposed COPD control…”
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Oral supplementation with whey proteins increases plasma glutathione levels of HIV-infected patients by Micke, P., Beeh, K. M., Schlaak, J. F., Buhl, R.

“…HIV infection is characterized by an enhanced oxidant burden and a systemic deficiency of the tripeptide glutathione (GSH), a major antioxidant. The…”
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Antiinflammatory properties of ambroxol by Beeh, K M, Beier, J, Esperester, A, Paul, L D

“…Ambroxol is frequently used as mucolytic agent in respiratory diseases associated with increased mucus production like acute or chronic bronchitis. Further,…”
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Effects of long-term supplementation with whey proteins on plasma glutathione levels of HIV-infected patients by Micke, P, Beeh, K. M, Buhl, R

“…Background HIV infection is characterized by an enhanced oxidant burden and a systemic deficiency of the tripeptide glutathione (GSH), a major antioxidant. The…”
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Which patients should be treated with anti-IgE? by M. Beeh, K

“…CORRESPONDENCE: K-M Beeh, insaf Respiratory Research Institute, Biebricher Allee 34, D-65187 Wiesbaden, Germany. Fax: 49 6119854348. E-mail:…”
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Newly diagnosed chronic obstructive pulmonary disease. Clinical features and distribution of the novel stages of the Global Initiative for Obstructive Lung Disease by Kornmann, O, Beeh, K M, Beier, J, Geis, U P, Ksoll, M, Buhl, R

“…The new guidelines of the Global Initiative for Obstructive Lung Disease (GOLD) propose a novel staging system for COPD. This study describes the frequency…”
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Sputum induction leads to a decrease of exhaled nitric oxide unrelated to airflow by Beier, J, Beeh, K.M, Kornmann, O, Buhl, R

“…Measurement of exhaled nitric oxide (eNO) and analysis of induced sputum are both established noninvasive methods for studying airway inflammation in asthma…”
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Induced sputum cell profiles in lung transplant recipients with or without chronic rejection: correlation with lung function by Beeh, K M, Kornmann, O, Lill, J, Buhl, R

“…BACKGROUND Sputum induction is a non-invasive procedure for measuring inflammatory processes of the lower respiratory tract. The aim of this study was to…”
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Indacaterol, a novel inhaled β2-agonist, provides sustained 24-h bronchodilation in asthma by BEEH, K. M, DEROM, E, KANNIESS, F, CAMERON, R, HIGGINS, M, VAN ASH, A

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Stability of glutathione in induced sputum: impact of freezing by Beier, J, Beeh, K M, Kornmann, O, Buhl, R

“…Oxidative stress has repeatedly been linked to the pathogenesis of pulmonary disorders like asthma and chronic obstructive pulmonary disease. Measuring…”
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ACTIVATE: the effect of aclidinium/formoterol on hyperinflation, exercise capacity, and physical activity in patients with COPD by Watz, Henrik, Troosters, Thierry, Beeh, Kai M, Garcia-Aymerich, Judith, Paggiaro, Pierluigi, Molins, Eduard, Notari, Massimo, Zapata, Antonio, Jarreta, Diana, Garcia Gil, Esther

“…The Phase IV, 8-week, randomized, double-blind, placebo-controlled ACTIVATE study (NCT02424344) evaluated the effect of aclidinium/formoterol (AB/FF) 400/12 μg…”
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Comparison of Dry-Powder Inhaler and Pressurized Metered-Dose Inhaler Formulations of Extrafine Beclomethasone Dipropionate/Formoterol Fumarate/Glycopyrronium in Patients with COPD: The TRI-D Randomized Controlled Trial by Beeh, Kai-Michael, Kuna, Piotr, Corradi, Massimo, Viaud, Isabelle, Guasconi, Alessandro, Georges, George

“…Three 52-week studies in COPD have assessed the efficacy and safety of single-inhaler extrafine formulation triple therapy combining beclomethasone…”
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