Search Results - "Beecher, Chris"
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Comparative physiological and metabolomics analysis of wheat (Triticum aestivum L.) following post-anthesis heat stress
Published in PloS one (13-06-2018)“…Genetic improvement for stress tolerance requires a solid understanding of biochemical processes involved with different physiological mechanisms and their…”
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Establishing a framework for best practices for quality assurance and quality control in untargeted metabolomics
Published in Metabolomics (12-02-2024)“…Background Quality assurance (QA) and quality control (QC) practices are key tenets that facilitate study and data quality across all applications of…”
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Metabolomics of primary cutaneous melanoma and matched adjacent extratumoral microenvironment
Published in PloS one (27-10-2020)“…Melanoma causes the vast majority of deaths attributable to skin cancer, largely due to its propensity for metastasis. To date, few studies have examined…”
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An overview of methods using 13C for improved compound identification in metabolomics and natural products
Published in Frontiers in plant science (25-08-2015)“…Compound identification is a major bottleneck in metabolomics studies. In nuclear magnetic resonance (NMR) investigations, resonance overlap often hinders…”
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5
Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos)
Published in Journal of agricultural and food chemistry (01-10-1997)“…The fruits of Physalis philadelphica, known commonly as tomatillos, are an ingredient of the condiment “salsa verde”. As part of an ongoing project to discover…”
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Isotopic ratio outlier analysis improves metabolomics prediction of nitrogen treatment in maize
Published in Phytochemistry (Oxford) (01-08-2019)“…We evaluated Isotope Ratio Outlier Analysis (IROA) as a metabolome-wide internal standard approach to improve the quality of LC/MS data collected from a…”
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Exploring the external exposome using wearable passive samplers - The China BAPE study
Published in Environmental pollution (1987) (01-02-2021)“…Environmental exposures are one of the greatest threats to human health, yet we lack tools to answer simple questions about our exposures: what are our…”
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Isotopic Ratio Outlier Analysis (IROA) for Quantitative Analysis
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2019)“…There is always a tension within the omics sciences between trying to measure biological molecules rapidly and measuring accurately. Metabolomics as an omics…”
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Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC)
Published in Metabolomics (09-04-2022)“…Introduction The metabolomics quality assurance and quality control consortium (mQACC) is enabling the identification, development, prioritization, and…”
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10
Comparative physiological and metabolomics analysis of wheat
Published in PloS one (13-06-2018)“…Genetic improvement for stress tolerance requires a solid understanding of biochemical processes involved with different physiological mechanisms and their…”
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11
Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC–MS based untargeted metabolomics practitioners
Published in Metabolomics (12-10-2020)“…Introduction The metabolomics quality assurance and quality control consortium (mQACC) evolved from the recognized need for a community-wide consensus on…”
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Addressing the current bottlenecks of metabolomics: Isotopic Ratio Outlier Analysis™, an isotopic-labeling technique for accurate biochemical profiling
Published in Bioanalysis (01-09-2012)“…Metabolomics or biochemical profiling is a fast emerging science; however, there are still many associated bottlenecks to overcome before measurements will be…”
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Isotopic Ratio Outlier Analysis of the S. cerevisiae Metabolome Using Accurate Mass Gas Chromatography/Time-of-Flight Mass Spectrometry: A New Method for Discovery
Published in Analytical chemistry (Washington) (01-03-2016)“…Isotopic ratio outlier analysis (IROA) is a 13C metabolomics profiling method that eliminates sample to sample variance, discriminates against noise and…”
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Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery
Published in The journal of maternal-fetal & neonatal medicine (01-12-2010)“…Objective. Biomarkers for preterm labor (PTL) and delivery can be discovered through the analysis of the transcriptome (transcriptomics) and protein…”
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Isotopic Ratio Outlier Analysis Global Metabolomics of Caenorhabditis elegans
Published in Analytical chemistry (Washington) (17-12-2013)“…We demonstrate the global metabolic analysis of Caenorhabditis elegans stress responses using a mass-spectrometry-based technique called isotopic ratio outlier…”
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Targeting pheochromocytoma/paraganglioma with polyamine inhibitors
Published in Metabolism, clinical and experimental (01-09-2020)“…Pheochromocytomas (PCCs) and paragangliomas (PGLs) are neuroendocrine tumors that are mostly benign. Metastatic disease does occur in about 10% of cases of PCC…”
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Quantitative Metabolomics Using Isotope Residue Outlier Analysis (IROA ® ) with Internal Standards
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2019)“…Various research strategies involving biomarker discovery and mechanistic studies in system biology depend on reproducible and reliable quantification of all…”
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Isotopic Ratio Outlier Analysis (IROA) of the S. cerevisiae metabolome using accurate mass GC-TOF/MS: A new method for discovery
Published in Analytical chemistry (Washington) (17-02-2016)“…Isotopic Ratio Outlier Analysis (IROA) is a 13 C metabolomics profiling method that eliminates sample-to-sample variance, discriminates against noise and…”
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Metabolomics and Natural-Products Strategies to Study Chemical Ecology in Nematodes
Published in Integrative and comparative biology (01-09-2015)“…This review provides an overview of two complementary approaches to identify biologically active compounds for studies in chemical ecology. The first is…”
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Metabolomic analysis reveals novel small molecule plasma markers of hyperacute ischemic stroke (S30.001)
Published in Neurology (06-04-2015)“…Abstract only…”
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