Search Results - "Beecham, J E"

Bypassing Immunization: Optimized Design of “Designer T Cells” against Carcinoembryonic Antigen (CEA)-expressing Tumors, and Lack of Suppression by Soluble CEA by NOLAN, K. F, YUN, C.-O, AKAMATSU, Y, MURPHY, J. C, LEUNG, S.-O, BEECHAM, E. J, JUNGHANS, R. P

“…Tumor-associated antigens are typically nonimmunogenic in cancer patients, “immune surveillance” having manifestly failed. The fact that most tumor antigens…”
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Targeting of T Lymphocytes to Melanoma Cells Through Chimeric Anti-GD3 Immunoglobulin T-Cell Receptors by Yun, C.O., Nolan, K.F., Beecham, E.J., Reisfeld, R.A., Junghans, P.

“…Immunoglobulin T-cell receptors (IgTCRs) combine the specificity of antibodies with the potency of cellular killing by grafting antibody recognition domains…”
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Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells by LeDoux, S P, Wilson, G L, Beecham, E J, Stevnsner, T, Wassermann, K, Bohr, V A

“…Using methodology recently developed to assess gene-specific DNA repair, we have demonstrated that it is possible not only to study mitochondrial DNA repair,…”
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Activated neutrophils induce prolonged DNA damage in neighboring cells by Shacter, E, Beecham, E J, Covey, J M, Kohn, K W, Potter, M

“…We have measured the capacity of highly-purified, paraffin oil-elicited neutrophils to induce DNA single-strand breaks in a newly established plasmacytoma cell…”
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Dynamics of tumor cell killing by human T lymphocytes armed with an anti-carcinoembryonic antigen Chimeric immunoglobulin T-cell receptor by BEECHAM, E. J, ORTIZ-PUJOLS, S, JUNGHANS, R. P

“…Chimeric immunoglobulin T-cell receptors (IgTCR) join the antigen-binding portion of an antibody to one of the signaling chains of the TCR. A previous report…”
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Coupling CD28 Co-stimulation to Immunoglobulin T-cell receptor molecules : The dynamics of T-cell proliferation and death by BEECHAM, E. Jeffrey, QIANGZHONG MA, RIPLEY, Robin, JUNGHANS, Richard P

“…Immunoglobulin T-cell receptor (IgTCR) molecules are potentially potent immune response modifiers because they allow T cells to bypass tolerance. Tolerance to…”
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Decoupling of DNA excision repair and RNA transcription in translocation breaksite regions of plasmacytoma-susceptible BALB/cAnPt mice by BEECHAM, E. J, OWENS, J. D, SHAUGHNESSY, J. D, HUPPI, K, BOHR, V. A, MUSHINSKI, J. F

“…Preferential repair of pyrimidine dimers in rodent cells is thought to be directly coupled to the RNA transcription machinery. The most compelling evidence for…”
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DNA repair in the c-myc proto-oncogene locus: possible involvement in susceptibility or resistance to plasmacytoma induction in BALB/c mice by BEECHAM, E. J, MUSHINSKI, J. F, SHACTER, E, POTTER, M, BOHR, V. A

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DNA repair defects associated with chromosomal translocation breaksite regions by BEECHAM, E. J, JONES, G. M, LINK, C, HUPPI, K, POTTER, M, MUSHINSKI, J. F, BOHR, V. A

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DNA damage induced by phorbol ester-stimulated neutrophils is augmented by extracellular cofactors. Role of histidine and metals by Shacter, E, Lopez, R L, Beecham, E J, Janz, S

“…Activated neutrophils cause extensive DNA damage in neighboring nonphagocytic cells. To determine whether compounds in the extracellular milieu participate in…”
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Restriction mapping of retroviral vector episomal DNA by Young, W B, Beecham, E J, Lindberg, G L, Link, Jr, C J

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Fine needle aspiration biopsy of peripheral congenital bronchial cyst by Beecham, J E

“…Bronchial cysts usually occur centrally near the mediastinum, but may present as a peripheral "coin" lesion requiring distinction from other causes of coin…”
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Burn wound carcinoma: case report and review of the literature by Abbas, J S, Beecham, J E

“…A 22-year-old man developed squamous cell carcinoma of the exophytic papillary type following a latent period of 14 years in a burn scar overlying the left…”
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Coexistent disease as a complicating factor in the fine needle aspiration diagnosis of papillary carcinoma of the thyroid by Beecham, J E

“…The occasional coexistence of papillary carcinoma of the thyroid with nodular goiter or hyperparathyroidism may in some cases result in a significant…”
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DNA repair in the c-myc locus by Beecham, E J, Mushinski, J F, Shacter, E, Potter, M, Bohr, V A

“…We have studied DNA repair after UV damage in the murine c-myc locus. It appears that a region in B cells upstream of the murine c-myc gene is repaired with a…”
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Less Repair of Pyrimidine Dimers and Single-Strand Breaks in Genes by Scid Cells by Alrefai, Rudaina H., Beecham, E.Jeffrey, Bohr, Vilhelm A., Gearhart, Patricia J.

“…Severe combined immunodeficient (Scid) mice have a mutation in the catalytic subunit of the DNA binding protein kinase that is involved in repair of…”
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DNA repair in the endogenous and episomal amplified c-myc oncogene loci in human tumor cells by Larminat, F, Beecham, E J, Link, Jr, C J, May, A, Bohr, V A

“…We have studied the repair of u.v.-induced cyclobutane pyrimidine dimers (CPDs) in amplified c-myc oncogene loci in human colon cancer cells to better…”
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Villous adenoma of the rectum diagnosed during labor by Schwartz, M L, Beecham, J E

“…A villous adenoma of the rectum was first discovered when it was forced through the anal canal during the second stage of labor. This is the first case of its…”
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Intramuscular hemangioma of the head and neck: report of a case involving the prevertebral muscles by Beecham, J E, Behrens, H W

“…Intramuscular hemangioma, a distinctive type of hemangioma occurring within skeletal muscle, accounts for approximately 1% of all hemangiomas. Most occur in…”
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DNA Damage induced by phorbol ester-stimulated neutrophil is augmented by extracellular cofactors: role of histidine and metals by SHACTER, E, LOPEZ, R. L, BEECHAM, E. J, JANZ, S

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