Search Results - "Beech, Claire"

The Preparation of a New “Safety Catch” Ester Linker for Solid-Phase Synthesis by Beech, Claire L, Coope, John F, Fairley, Gary, Gilbert, Philip S, Main, Brian G, Plé, Karen

“…A new “safety catch” linker for esters has been synthesized on polystyrene resin. This 2-tert-butoxyphenol resin 10 may be acylated to give a relatively stable…”
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Discovery of potent CRTh2 (DP 2) receptor antagonists by Birkinshaw, Timothy N., Teague, Simon J., Beech, Claire, Bonnert, Roger V., Hill, Stephen, Patel, Anil, Reakes, Sara, Sanganee, Hitesh, Dougall, Iain G., Phillips, Tim T., Salter, Sylvia, Schmidt, Jerzy, Arrowsmith, Elizabeth C., Carrillo, Juan J., Bell, Fiona M., Paine, Stuart W., Weaver, Richard

“…The discovery and optimisation of potent antagonists of the CRTh2 receptor is described culminating in the synthesis of 12, a novel, potent, selective and…”
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