Search Results - "Beebe, M"

Length-Dependent Transport in Molecular Junctions Based on SAMs of Alkanethiols and Alkanedithiols:  Effect of Metal Work Function and Applied Bias on Tunneling Efficiency and Contact Resistance by Engelkes, Vincent B, Beebe, Jeremy M, Frisbie, C. Daniel

“…Nanoscopic tunnel junctions were formed by contacting Au-, Pt-, or Ag-coated atomic force microscopy (AFM) tips to self-assembled monolayers (SAMs) of…”
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IL-10 Elicits IFNγ-Dependent Tumor Immune Surveillance by Mumm, John B., Emmerich, Jan, Zhang, Xueqing, Chan, Ivan, Wu, Lingling, Mauze, Smita, Blaisdell, Steven, Basham, Beth, Dai, Jie, Grein, Jeff, Sheppard, Catherine, Hong, Kyu, Cutler, Collette, Turner, Scott, LaFace, Drake, Kleinschek, Melanie, Judo, Michael, Ayanoglu, Gulesi, Langowski, John, Gu, Danling, Paporello, Brittany, Murphy, Erin, Sriram, Venkataraman, Naravula, Saraswathi, Desai, Bela, Medicherla, Satya, Seghezzi, Wolfgang, McClanahan, Terrill, Cannon-Carlson, Susan, Beebe, Amy M., Oft, Martin

“…Tumor immune surveillance and cancer immunotherapies are thought to depend on the intratumoral infiltration of activated CD8 + T cells. Intratumoral CD8 +…”
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Transition from direct tunneling to field emission in metal-molecule-metal junctions by Beebe, Jeremy M, Kim, BongSoo, Gadzuk, J W, Frisbie, C Daniel, Kushmerick, James G

“…Current-voltage measurements of metal-molecule-metal junctions formed from pi-conjugated thiols exhibit an inflection point on a plot of ln(I/V(2)) vs 1/V,…”
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Correlation between HOMO Alignment and Contact Resistance in Molecular Junctions:  Aromatic Thiols versus Aromatic Isocyanides by Kim, Beebe, Jeremy M, Jun, Yongseok, Zhu, X.-Y, Frisbie, C. Daniel

“…Understanding electron transport in metal−molecule−metal (MMM) junctions is of great importance for the advancement of molecular electronics. Critical factors…”
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Contact Resistance in Metal−Molecule−Metal Junctions Based on Aliphatic SAMs:  Effects of Surface Linker and Metal Work Function by Beebe, Jeremy M, Engelkes, Vincent B, Miller, Larry L, Frisbie, C. Daniel

“…Using conducting probe atomic force microscopy (CP-AFM), we have formed molecular tunnel junctions consisting of alkanethiols and alkane isonitrile…”
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Temperature and Length Dependence of Charge Transport in Redox-Active Molecular Wires Incorporating Ruthenium(II) Bis(σ-arylacetylide) Complexes by Kim, Beebe, Jeremy M, Olivier, Céline, Rigaut, Stéphane, Touchard, Daniel, Kushmerick, James G, Zhu, X.-Y, Frisbie, C. Daniel

“…We report the electrical transport behavior of a series of redox-active conjugated molecular wires as a function of temperature and molecular length. The wires…”
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Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice by Murphy, Judith T., Burey, Andre P., Beebe, Amy M., Gu, Danling, Presta, Leonard G., Merghoub, Taha, Wolchok, Jedd D.

“…Immunotherapy for cancer using antibodies to enhance T-cell function has been successful in recent clinical trials. Many molecules that improve activation and…”
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The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS) by Beebe, Amy M, Cua, Daniel J, de Waal Malefyt, Rene

“…Interleukin-10 (IL-10) is an immunoregulatory cytokine that plays a crucial role in inflammatory and immune reactions. It has potent anti-inflammatory and…”
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Tracing electronic pathways in molecules by using inelastic tunneling spectroscopy by Troisi, Alessandro, Beebe, Jeremy M, Picraux, Laura B, van Zee, Roger D, Stewart, Duncan R, Ratner, Mark A, Kushmerick, James G

“…Using inelastic electron tunneling spectroscopy (IETS) to measure the vibronic structure of nonequilibrium molecular transport, aided by a quantitative…”
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The Role of Anti-Drug Antibodies in the Pharmacokinetics, Disposition, Target Engagement, and Efficacy of a GITR Agonist Monoclonal Antibody in Mice by Brunn, Nicholas D, Mauze, Smita, Gu, Danling, Wiswell, Derek, Ueda, Roanna, Hodges, Douglas, Beebe, Amy M, Zhang, Shuli, Escandón, Enrique

“…Administration of biologics to enhance T-cell function is part of a rapidly growing field of cancer immunotherapy demonstrated by the unprecedented clinical…”
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Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy by Guelen, Lars, Fischmann, Thierry O, Wong, Jerelyn, Mauze, Smita, Guadagnoli, Marco, Bąbała, Nikolina, Wagenaars, Jozef, Juan, Veronica, Rosen, David, Prosise, Winnie, Habraken, Maurice, Lodewijks, Imke, Gu, Danling, Stammen-Vogelzangs, Judith, Yu, Ying, Baker, Jeanne, Lutje Hulsik, David, Driessen-Engels, Lilian, Malashock, Dan, Kreijtz, Joost, Bertens, Astrid, de Vries, Evert, Bovens, Astrid, Bramer, Arne, Zhang, Yiwei, Wnek, Richard, Troth, Sean, Chartash, Elliot, Dobrenkov, Konstantin, Sadekova, Svetlana, van Elsas, Andrea, Cheung, Jason K, Fayadat-Dilman, Laurence, Borst, Jannie, Beebe, Amy M, Van Eenennaam, Hans

“…BackgroundImmune checkpoint inhibitors (ICI) have radically changed cancer therapy, but most patients with cancer are unresponsive or relapse after treatment…”
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Surface plasmon resonance modulation in nanopatterned Au gratings by the insulator-metal transition in vanadium dioxide films by Beebe, M, Wang, L, Madaras, S E, Klopf, J M, Li, Z, Brantley, D, Heimburger, M, Wincheski, R A, Kittiwatanakul, S, Lu, J, Wolf, S A, Lukaszew, R A

“…Correlated experimental and simulation studies on the modulation of Surface Plasmon Polaritons (SPP) in Au/VO2 bilayers are presented. The modification of the…”
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Vibronic Coupling in Semifluorinated Alkanethiol Junctions:  Implications for Selection Rules in Inelastic Electron Tunneling Spectroscopy by Beebe, Jeremy M, Moore, H. Justin, Lee, T. Randall, Kushmerick, James G

“…Determining the selection rules for the interaction of tunneling charge carriers with molecular vibrational modes is important for a complete understanding of…”
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Impaired NFATc Translocation and Failure of Th2 Development in Itk-Deficient CD4 + T Cells by Fowell, Deborah J, Shinkai, Kanade, Liao, X.Charlene, Beebe, Amy M, Coffman, Robert L, Littman, Dan R, Locksley, Richard M

“…Naive Itk-deficient CD4 + T cells were unable to establish stable IL-4 production, even when primed in Th2-inducing conditions. In contrast, IFNγ production…”
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Analysis of the Causes of Variance in Resistance Measurements on Metal−Molecule−Metal Junctions Formed by Conducting-Probe Atomic Force Microscopy by Engelkes, Vincent B, Beebe, Jeremy M, Frisbie, C. Daniel

“…Alkanethiol tunnel junctions were studied using conducting-probe atomic force microscopy to determine causes of variability in measured resistance behavior…”
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Ccr4-Not maintains genomic integrity by controlling the ubiquitylation and degradation of arrested RNAPII by Jiang, Haoyang, Wolgast, Marley, Beebe, Laura M, Reese, Joseph C

“…The Ccr4-Not complex regulates essentially every aspect of gene expression, from mRNA synthesis to protein destruction. The Not4 subunit of the complex…”
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Non-Fluorinated, Superhydrophobic Binder-Filler Coatings on Smooth Surfaces: Controlled Phase Separation of Particles to Enhance Mechanical Durability by Li, Chao, Boban, Mathew, Beebe, Jeremy M, Bhagwagar, Dorab E, Liu, Junying, Tuteja, Anish

“…There has been a recent drive to develop non-fluorinated superhydrophobic coatings due to the toxicity, cost, and environmental impact of perfluorinated…”
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Dual Roles for Regulatory T-cell Depletion and Costimulatory Signaling in Agonistic GITR Targeting for Tumor Immunotherapy by Mahne, Ashley E, Mauze, Smita, Joyce-Shaikh, Barbara, Xia, Jane, Bowman, Edward P, Beebe, Amy M, Cua, Daniel J, Jain, Renu

“…Agonistic monoclonal antibodies (mAb) targeting the T-cell receptor coregulatory molecule GITR exert potent therapeutic activities in preclinical tumor models…”
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Characteristics and survival patterns of solid organ Transplant patients developing de novo colon and rectal Cancer by PAPACONSTANTINOU, Harry T, SKLOW, Bradford, HANAWAY, Michael J, GROSS, Thomas G, BEEBE, Thomas M, TROFE, Jennifer, ALLOWAY, Rita R, WOODLE, E. Steve, BUELL, Joseph F

“…Immunosuppression used in transplantation is associated with an increased incidence of various cancers. Although the incidence of colorectal cancer in…”
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Measuring Relative Barrier Heights in Molecular Electronic Junctions with Transition Voltage Spectroscopy by Beebe, Jeremy M, Kim, BongSoo, Frisbie, C. Daniel, Kushmerick, James G

“…Though molecular devices exhibiting potentially useful electrical behavior have been demonstrated, a deep understanding of the factors that influence charge…”
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