Search Results - "Beebe, K"

Organization of the human superior olivary complex in 15q duplication syndromes and autism spectrum disorders by Lukose, R, Beebe, K, Kulesza, R.J

“…Highlights • Subjects with ASD and dup(15q) have fewer SOC neurons than controls. • Neuronal cell bodies in the SOC of ASD subjects are smaller than controls…”
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Distribution of fragile X mental retardation protein in the human auditory brainstem by Beebe, K, Wang, Y, Kulesza, R

“…Highlights • FMRP is widely expressed in human brainstem neurons. • Nearly all bushy and octopus cells in the VCN are FMRP-immunoreactive. • FMRP is prominent…”
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Efficacy and Safety of Paroxetine Treatment for Chronic PTSD: A Fixed-Dose, Placebo-Controlled Study by Marshall, Randall D., Beebe, Katherine L., Oldham, Mary, Zaninelli, Rocco

“…OBJECTIVE: This study evaluated the efficacy and safety of paroxetine for the treatment of patients with chronic posttraumatic stress disorder (PTSD). METHOD:…”
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Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability by Beebe, Kirk, de Pouplana, Lluis Ribas, Schimmel, Paul

“…Editing of misactivated amino acids by class I tRNA synthetases is encoded by a specialized internal domain specific to class I enzymes. In contrast, little is…”
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Sensitivity of epidermal growth factor receptor and ErbB2 exon 20 insertion mutants to Hsp90 inhibition by XU, W, SOGA, S, BEEBE, K, LEE, M. J, KIM, Y. S, TREPEL, J, NECKERS, L

“…The mature epidermal growth factor receptor (EGFR) neither associates with nor requires the molecular chaperone heat-shock protein 90 (Hsp90). Mutations in…”
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Certification status of family physicians in the initial cohort entering maintenance of certification by Puffer, James C, Bazemore, Andrew W, Phillips, Robert L, Beebe, Diane K

“…There existed considerable concern that participation in Maintenance of Certification by board-certified physicians would be less than optimal when it was…”
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Single-bone forearm reconstruction for malignant and aggressive tumors by Kesani, A K, Tuy, B, Beebe, K, Patterson, F, Benevenia, J

“…Limb-salvage surgery for malignant and aggressive forearm tumors presents a unique surgical challenge. We performed single-bone forearm reconstructions after…”
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A Seasonally Breeding Tropical Bird Lacks Absolute Photorefractoriness in the Wild, Despite High Photoperiodic Sensitivity by Beebe, K., Bentley, G. E., Hau, M.

“…1. Photoperiod is an important seasonal cue for temperate seasonal breeders. In birds, increasing photoperiod typically stimulates reproductive maturation,…”
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The efficacy of mifepristone in the reduction and prevention of olanzapine-induced weight gain in rats by Beebe, Katherine L., Block, Thaddeus, DeBattista, Charles, Blasey, Christine, Belanoff, Joseph K.

“…Atypical antipsychotics, such as olanzapine, have been associated with clinically significant weight gain. Changes to the hypothalamic pituitary adrenal axis…”
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Determination of the Binding Specificity of the SH2 Domains of Protein Tyrosine Phosphatase SHP-1 through the Screening of a Combinatorial Phosphotyrosyl Peptide Library by Beebe, Kirk D, Wang, Peng, Arabaci, Gulnur, Pei, Dehua

“…A method for the rapid identification of high-affinity ligands to Src homology-2 (SH2) domains is reported. A phosphotyrosyl (pY) peptide library containing…”
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A-04 One Size Fits None: Neurobiologic-Specific Modifications For The Assessment, Diagnosis, and Treatment of Sport-Related Concussion by Beebe, K E, Reynolds, E

“…Abstract Objective The primary objective of this review paper is to introduce the underlying neurobiology of concussion symptoms, including relevant…”
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National Institute for Program Director Development (NIPDD): A Collaborative Pursuit of Excellence by Palmer, Elissa J., MD, Tippy, Penelope K., MD, Bope, Edward T., MD, Gillanders, William R., MD, Pugno, Perry A., MD, MPH CPE, Goertz, Roland A., MD MBA, Puffer, James C., MD, Beebe, Diane K., MD, Mygdal, William K., EdD, Cullison, Sam, MD, Hanova, Amanda L., AFMRD, Fickel, Nicole A., AFMRD

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II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides by Wang, P, Byeon, I J, Liao, H, Beebe, K D, Yongkiettrakul, S, Pei, D, Tsai, M D

“…The forkhead-associated (FHA) domain is a protein module found in many proteins involved in cell signaling in response to DNA damage. It has been suggested to…”
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Identification of novel insulin resistance metabolites in a non-diabetic population by global biochemical profiling by Ferrannini, E, Gall, W, Nannipieri, M, Anselmino, M, Rossi, M, Beebe, K, Adam, K.P, Ryals, J, Milburn, M

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Long-term bisphosphonate usage and subtrochanteric insufficiency fractures: A CAUSE FOR CONCERN? by YOON, R. S, HWANG, J. S, BEEBE, K. S

“…For over a decade, bisphosphonate administration has evolved and become the cornerstone of the prevention and treatment of fragility fractures. Millions of…”
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1960P Differential induction of gene expression may explain differences in reported adverse event profiles between the FGFR-inhibitors derazantinib and erdafitinib: An analysis in safety relevant normal tissues from urothelial cancer (UC) patient-derived mouse xenograft (PDX) models by McSheehy, P., Guo, J., Beebe, K., Eisner, J.R., Anderson, S., Braun, S., Engelhardt, M., Kellenberger, L., Lane, H., Milburn, M.

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Substrate Recognition through a PDZ Domain in Tail-Specific Protease by Beebe, Kirk D, Shin, Jinu, Peng, Jing, Chaudhury, Chaity, Khera, Jena, Pei, Dehua

“…Tail-specific protease (Tsp) is a periplasmic enzyme that selectively degrades proteins bearing a nonpolar C-terminus. Its substrate specificity suggests that…”
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Smokable methamphetamine ('ice'): an old drug in a different form by Beebe, D K, Walley, E

“…Methamphetamine has long been a drug of abuse. The smokable form of methamphetamine hydrochloride, called "ice" on the street, is twice as toxic as amphetamine…”
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Autosomal dominant polycystic kidney disease by Beebe, D K

“…Autosomal dominant polycystic kidney disease is one of the most commonly inherited diseases in the United States. It affects nearly 500,000 Americans and…”
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Caring for infants with congenital heart disease and their families by Saenz, R B, Beebe, D K, Triplett, L C

“…Congenital heart defects are classified into two broad categories: acyanotic and cyanotic lesions. The most common acyanotic lesions are ventricular septal…”
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