Search Results - "Bedrosian, Isabelle"

Management of Hereditary Breast Cancer: American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology Guideline by Tung, Nadine M, Boughey, Judy C, Pierce, Lori J, Robson, Mark E, Bedrosian, Isabelle, Dietz, Jill R, Dragun, Anthony, Gelpi, Judith Balmana, Hofstatter, Erin W, Isaacs, Claudine J, Jatoi, Ismail, Kennedy, Elaine, Litton, Jennifer K, Mayr, Nina A, Qamar, Rubina D, Trombetta, Mark G, Harvey, Brittany E, Somerfield, Mark R, Zakalik, Dana

“…To develop recommendations for management of patients with breast cancer (BC) with germline mutations in BC susceptibility genes. The American Society of…”
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Circulating tumour cells in non-metastatic breast cancer: a prospective study by Lucci, Anthony, Prof, Hall, Carolyn S, PhD, Lodhi, Ashutosh K, MD, Bhattacharyya, Anirban, MD, Anderson, Amber E, BS, Xiao, Lianchun, MS, Bedrosian, Isabelle, MD, Kuerer, Henry M, Prof, Krishnamurthy, Savitri, Prof

“…Summary Background The identification of circulating tumour cells correlate with poor prognosis in metastatic breast cancer, but there are few data describing…”
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Gene signature associated with resistance to fluvastatin chemoprevention for breast cancer by Bhardwaj, Anjana, Embury, Matthew D, Ju, Zhenlin, Wang, Jing, Bedrosian, Isabelle

“…Although targeting of the cholesterol pathway by statins prevents breast cancer development in mouse models, efficacy is not absolute. Therefore, the goal of…”
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Locoregional Control According to Breast Cancer Subtype and Response to Neoadjuvant Chemotherapy in Breast Cancer Patients Undergoing Breast-conserving Therapy by Swisher, Shannon K., Vila, Jose, Tucker, Susan L., Bedrosian, Isabelle, Shaitelman, Simona F., Litton, Jennifer K., Smith, Benjamin D., Caudle, Abigail S., Kuerer, Henry M., Mittendorf, Elizabeth A.

“…Background Our group previously published data showing that patients could be stratified by constructed molecular subtype with respect to locoregional…”
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The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer by Bhardwaj, Anjana, Singh, Harpreet, Trinidad, Celestine Marie, Albarracin, Constance T, Hunt, Kelly K, Bedrosian, Isabelle

“…Prevention of triple-negative breast cancer (TNBC) is hampered by lack of knowledge about the drivers of tumorigenesis. To identify molecular markers and their…”
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The molecular heterogeneity of the precancerous breast affects drug efficacy by Bhardwaj, Anjana, Rojo, Raniv Dawey, Ju, Zhenlin, Koh, Alexander, Tachibana, Kazunoshin, Wang, Jing, Bedrosian, Isabelle

“…In the therapeutic domain, targeted therapies have been shown to be generally more effective when given to patients with tumors that harbor the targeted…”
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Regulation of miRNA-29c and its downstream pathways in preneoplastic progression of triple-negative breast cancer by Bhardwaj, Anjana, Singh, Harpreet, Rajapakshe, Kimal, Tachibana, Kazunoshin, Ganesan, Nivetha, Pan, Yinghong, Gunaratne, Preethi H, Coarfa, Cristian, Bedrosian, Isabelle

“…Little is understood about the early molecular drivers of triple-negative breast cancer (TNBC), making the identification of women at risk and development of…”
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Evaluation of a Breast Cancer Nomogram for Predicting Risk of Ipsilateral Breast Tumor Recurrences in Patients With Ductal Carcinoma in Situ After Local Excision by Yi, Min, Meric-Bernstam, Funda, Kuerer, Henry M, Mittendorf, Elizabeth A, Bedrosian, Isabelle, Lucci, Anthony, Hwang, Rosa F, Crow, Jaime R, Luo, Sheng, Hunt, Kelly K

“…Prediction of patients at highest risk for ipsilateral breast tumor recurrence (IBTR) after local excision of ductal carcinoma in situ (DCIS) remains a…”
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Contralateral Prophylactic Mastectomy among Women with Pathogenic Variants in BRCA1/2: Overall Survival, Racial, and Ethnic Differences by Makhnoon, Sukh, Gutierrez Barrera, Angelica M., Bassett, Roland, Afrough, Aimaz, Bedrosian, Isabelle, Arun, Banu K.

“…Background. Patients with unilateral breast cancer carrying pathogenic variants in BRCA1/2 have the option to undergo contralateral prophylactic mastectomy…”
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Pan-cancer analysis reveals TAp63-regulated oncogenic lncRNAs that promote cancer progression through AKT activation by Napoli, Marco, Li, Xiaobo, Ackerman, Hayley D., Deshpande, Avani A., Barannikov, Ivan, Pisegna, Marlese A., Bedrosian, Isabelle, Mitsch, Jürgen, Quinlan, Philip, Thompson, Alastair, Rajapakshe, Kimal, Coarfa, Cristian, Gunaratne, Preethi H., Marchion, Douglas C., Magliocco, Anthony M., Tsai, Kenneth Y., Flores, Elsa R.

“…The most frequent genetic alterations across multiple human cancers are mutations in TP53 and the activation of the PI3K/AKT pathway, two events crucial for…”
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Outcomes after Treatment of Metaplastic Versus Other Breast Cancer Subtypes by Moreno, Amy C, Lin, Yan Heather, Bedrosian, Isabelle, Shen, Yu, Babiera, Gildy V, Shaitelman, Simona F

“…: Metaplastic breast cancer (BC) is an uncommon yet aggressive histologic subtype of BC. We sought to identify factors associated with its diagnosis and…”
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Prospective Evaluation of the Nipple–Areola Complex Sparing Mastectomy for Risk Reduction and for Early-Stage Breast Cancer by Wagner, Jamie L., Fearmonti, Regina, Hunt, Kelly K., Hwang, Rosa F., Meric-Bernstam, Funda, Kuerer, Henry M., Bedrosian, Isabelle, Crosby, Melissa A., Baumann, Donald P., Ross, Merrick I., Feig, Barry W., Krishnamurthy, Savitri, Hernandez, Mike, Babiera, Gildy V.

“…Background Psychological effects of mastectomy for women with breast cancer have driven treatments that optimize cosmesis while strictly adhering to oncologic…”
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Local-regional control according to surrogate markers of breast cancer subtypes and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast conserving therapy by Caudle, Abigail S, Yu, Tse-Kuan, Tucker, Susan L, Bedrosian, Isabelle, Litton, Jennifer K, Gonzalez-Angulo, Ana M, Hoffman, Karen, Meric-Bernstam, Funda, Hunt, Kelly K, Buchholz, Thomas A, Mittendorf, Elizabeth A

“…Breast cancers of different molecular subtypes have different survival rates. The goal of this study was to identify patients at high risk for local-regional…”
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Automatic Segmentation of Whole Breast Using Atlas Approach and Deformable Image Registration by Reed, Valerie K., M.D, Woodward, Wendy A., M.D., Ph.D, Zhang, Lifei, Ph.D, Strom, Eric A., M.D, Perkins, George H., M.D, Tereffe, Welela, M.D, Oh, Julia L., M.D, Yu, T. Kuan, M.D., Ph.D, Bedrosian, Isabelle, M.D, Whitman, Gary J., M.D, Buchholz, Thomas A., M.D, Dong, Lei, Ph.D

“…Purpose To compare interobserver variations in delineating the whole breast for treatment planning using two contouring methods. Methods and Materials…”
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Annexin A1 Preferentially Predicts Poor Prognosis of Basal-Like Breast Cancer Patients by Activating mTOR-S6 Signaling by Bhardwaj, Anjana, Ganesan, Nivetha, Tachibana, Kazunoshin, Rajapakshe, Kimal, Albarracin, Constance T, Gunaratne, Preethi H, Coarfa, Cristian, Bedrosian, Isabelle

“…Annexin A1 (ANXA1) is an anti-inflammatory protein reported to play a role in cell proliferation and apoptosis, and to be deregulated in breast cancer. The…”
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Circulating tumor cells in non-metastatic triple-negative breast cancer by Karhade, Mandar, Hall, Carolyn, Mishra, Priyankana, Anderson, Amber, Kuerer, Henry, Bedrosian, Isabelle, Krishnamurthy, Savitri, Lucci, Anthony

“…Circulating tumor cells (CTCs) can be identified in approximately 25 % of stage I-III breast cancer patients; CTCs presence is a predictor of poor outcome in…”
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Survival outcomes after omission of surgery for ductal carcinoma in situ by Poli, Elizabeth C., Dong, Wenli, Shaitelman, Simona F., Tamirisa, Nina, Shen, Yu, Bedrosian, Isabelle

“…Clinical trials of active surveillance (AS) for Ductal Carcinoma in Situ (DCIS) are underway. We sought to understand the historical management of biologically…”
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Ability to Generate Patient-Derived Breast Cancer Xenografts Is Enhanced in Chemoresistant Disease and Predicts Poor Patient Outcomes by McAuliffe, Priscilla F, Evans, Kurt W, Akcakanat, Argun, Chen, Ken, Zheng, Xiaofeng, Zhao, Hao, Eterovic, Agda Karina, Sangai, Takafumi, Holder, Ashley M, Sharma, Chandeshwar, Chen, Huiqin, Do, Kim-Anh, Tarco, Emily, Gagea, Mihai, Naff, Katherine A, Sahin, Aysegul, Multani, Asha S, Black, Dalliah M, Mittendorf, Elizabeth A, Bedrosian, Isabelle, Mills, Gordon B, Gonzalez-Angulo, Ana Maria, Meric-Bernstam, Funda

“…Breast cancer patients who are resistant to neoadjuvant chemotherapy (NeoCT) have a poor prognosis. There is a pressing need to develop in vivo models of chemo…”
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Chimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer by Mistretta, Brandon, Rankothgedera, Sakuni, Castillo, Micah, Rao, Mitchell, Holloway, Kimberly, Bhardwaj, Anjana, El Noafal, Maha, Albarracin, Constance, El-Zein, Randa, Rezaei, Hengameh, Su, Xiaoping, Akbani, Rehan, Shao, Xiaoshan M., Czerniecki, Brian J., Karchin, Rachel, Bedrosian, Isabelle, Gunaratne, Preethi H.

“…Introduction We present here a strategy to identify immunogenic neoantigen candidates from unique amino acid sequences at the junctions of fusion proteins…”
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Prospective, early longitudinal assessment of lymphedema-related quality of life among patients with locally advanced breast cancer: The foundation for building a patient-centered screening program by Gandhi, Anusha, Xu, Tianlin, DeSnyder, Sarah M., Smith, Grace L., Lin, Ruitao, Barcenas, Carlos H., Stauder, Michael C., Hoffman, Karen E., Strom, Eric A., Ferguson, Susan, Smith, Benjamin D., Woodward, Wendy A., Perkins, George H., Mitchell, Melissa P., Garner, Desmond, Goodman, Chelain R., Aldrich, Melissa, Travis, Marigold, Lilly, Susan, Bedrosian, Isabelle, Shaitelman, Simona F.

“…We examined how breast cancer-related lymphedema (BCRL) affects health-related quality of life (HRQOL), productivity, and compliance with therapeutic…”
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