Search Results - "Bedouet, Laurent"

Tunable delivery of niflumic acid from resorbable embolization microspheres for uterine fibroid embolization by Bédouet, Laurent, Moine, Laurence, Servais, Emeline, Beilvert, Anne, Labarre, Denis, Laurent, Alexandre

“…[Display omitted] Uterine arteries embolization (UAE) is a recent technique that aims, by means of particles injected percutaneously, to stifle fibroids…”
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Poly(ethylene glycol) methacrylate hydrolyzable microspheres for transient vascular embolization by Louguet, Stéphanie, Verret, Valentin, Bédouet, Laurent, Servais, Emeline, Pascale, Florentina, Wassef, Michel, Labarre, Denis, Laurent, Alexandre, Moine, Laurence

“…Poly(ethylene glycol) methacrylate (PEGMA) hydrolyzable microspheres intended for biomedical applications were readily prepared from poly(lactide-co-glycolide)…”
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Synthesis of hydrophilic intra-articular microspheres conjugated to ibuprofen and evaluation of anti-inflammatory activity on articular explants by Bédouet, Laurent, Moine, Laurence, Pascale, Florentina, Nguyen, Van-Nga, Labarre, Denis, Laurent, Alexandre

“…The main limitation of current microspheres for intra-articular delivery of non-steroidal anti-inflammatory drugs (NSAIDs) is a significant initial burst…”
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Coupling Proteomics and Transcriptomics for the Identification of Novel and Variant Forms of Mollusk Shell Proteins: A Study with P. margaritifera by Berland, Sophie, Marie, Arul, Duplat, Denis, Milet, Christian, Sire, Jean Yves, Bédouet, Laurent

“…Shell matrix proteins from Pinctada margaritifera were characterized by combining proteomics analysis of shell organic extracts and transcript sequences, both…”
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Lymphatic Transport and Lymph Node Location of Microspheres Subcutaneously Injected in the Vicinity of Tumors in a Rabbit Model of Breast Cancer by Pascale, Florentina, Bédouet, Laurent, Fazel, Afchine, Namur, Julien, Ghegediban, Saida Homayra, Cornil, Isabelle Schwartz, Wassef, Michel, Moine, Laurence, Laurent, Alexandre

“…Purpose To assess the lymphatic transport of microparticles of 100 nm, 1 μm and 10 μm subcutaneously injected into the breast area of healthy and tumor-bearing…”
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Intra-articular fate of degradable poly(ethyleneglycol)-hydrogel microspheres as carriers for sustained drug delivery by Bédouet, Laurent, Pascale, Florentina, Moine, Laurence, Wassef, Michel, Ghegediban, Saïda H., Nguyen, Van-Nga, Bonneau, Michel, Labarre, Denis, Laurent, Alexandre

“…A novel degradable microsphere (MS) for intra-articular drug delivery, composed of a polyethylene glycol (PEG) core containing degradable regions made of short…”
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Anti-angiogenic drug delivery from hydrophilic resorbable embolization microspheres: An in vitro study with sunitinib and bevacizumab by Bédouet, Laurent, Verret, Valentin, Louguet, Stéphanie, Servais, Emeline, Pascale, Florentina, Beilvert, Anne, Baylatry, Minh-Tâm, Labarre, Denis, Moine, Laurence, Laurent, Alexandre

“…[Display omitted] Anti-angiogenic (AA) drugs are proposed as novel agents for targeted therapies in hepatocellular carcinoma (HCC). Loading of AA drugs into…”
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In vitro evaluation of S-(+)-ibuprofen as drug candidate for intra-articular drug delivery system by Bédouet, Laurent, Pascale, Florentina, Bonneau, Michel, Laurent, Alexandre

“…Abstract Intra-articular drug delivery systems (DDSs) are envisaged as interesting alternative to locally release non-steroidal anti-inflammatory drugs…”
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bFGF Up-regulation Reduces Spontaneous Necrosis of VX2 Tumors Without Increasing Tumoral Microvascular Density by Pascale, Florentina, Ghegediban, Saida-Homayra, Bedouet, Laurent, Namur, Julien, Bonneau, Michel, Verret, Valentin, Schwartz-Cornil, Isabelle, Wassef, Michel, Laurent, Alex

“…To determine whether up-regulation of basic fibroblast growth factor (bFGF) in VX2 cells reduces tumor necrosis. VX2 cells were transfected with expression…”
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Proteomic and profile analysis of the proteins laced with aragonite and vaterite in the freshwater mussel Hyriopsis cumingii shell biominerals by Berland, Sophie, Ma, Yufei, Marie, Arul, Andrieu, Jean-Pierre, Bedouet, Laurent, Feng, Qingling

“…Hyriopsis cumingii (Lea, Unionidae), a freshwater bivalve species widely distributed in China and commercially exploited for freshwater pearl production, was…”
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Analysis of low complex region peptides derived from mollusk shell matrix proteins using CID, high-energy collisional dissociation, and electron transfer dissociation on an LTQ-orbitrap: Implications for peptide to spectrum match by Marie, Arul, Alves, Sandra, Marie, Benjamin, Dubost, Lionel, Bédouet, Laurent, Berland, Sophie

“…Identification of proteins involved in mollusk biomineralization by proteomics approach is gaining importance. These proteins are often characterized by…”
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Modified Model of VX2 Tumor Overexpressing Vascular Endothelial Growth Factor by Pascale, Florentina, PhD, Ghegediban, Saida-Homayra, MS, Bonneau, Michel, MS, Bedouet, Laurent, PhD, Namur, Julien, MS, Verret, Valentin, MS, Schwartz-Cornil, Isabelle, PhD, Wassef, Michel, MD, Laurent, Alexandre, PhD, MD

“…Abstract Purpose To determine whether upregulated expression of vascular endothelial growth factor (VEGF) in VX2 cells can increase vessel density (VD) and…”
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In vitro evaluation of (S)-ibuprofen toxicity on joint cells and explants of cartilage and synovial membrane by Bédouet, Laurent, Pascale, Florentina, Bonneau, Michel, Wassef, Michel, Laurent, Alexandre

“…► We examine the toxicity of (S)-ibuprofen on joint cells from sheep shoulder joint. ► (S)-ibuprofen at 50μm and 1mM is not toxic for chondrocytes and synovial…”
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IL6 and TNF expression in vessels and surrounding tissues after embolization with ibuprofen-loaded beads confirms diffusion of ibuprofen by Verret, Valentin, Bevilacqua, Claudia, Schwartz-Cornil, Isabelle, Pelage, Jean-Pierre, Wassef, Michel, Namur, Julien, Bédouet, Laurent, Lewis, Andrew L., Martin, Patrice, Laurent, Alexandre

“…Ibuprofen from loaded embolization beads released in tissues and induced over-expression of IL6 beyond the vascular wall, in the surrounding tissues, which…”
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Restoration of stratum corneum with nacre lipids by Rousseau, Marthe, Bédouet, Laurent, Lati, Elian, Gasser, Philippe, Le Ny, Karine, Lopez, Evelyne

“…To discover potential new products for the atopic dermatitis treatment, lipids extracted from nacre from the oyster Pinctada margaritifera were tested on…”
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The effect of molecules in mother-of-pearl on the decrease in bone resorption through the inhibition of osteoclast cathepsin K by Duplat, Denis, Gallet, Marlène, Berland, Sophie, Marie, Arul, Dubost, Lionel, Rousseau, Marthe, Kamel, Saïd, Milet, Christian, Brazier, Michel, Lopez, Evelyne, Bédouet, Laurent

“…Abstract This study evaluates the effect of the mother-of-pearl (nacre) organic matrix on mammalian osteoclast activity and on cathepsin K protease. Rabbit…”
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What is the difference in organic matrix of aragonite vs. vaterite polymorph in natural shell and pearl? Study of the pearl-forming freshwater bivalve mollusc Hyriopsis cumingii by Ma, Yufei, Berland, Sophie, Andrieu, Jean-Pierre, Feng, Qingling, Bédouet, Laurent

“…Aragonite pearl, vaterite pearl and shell nacre of the freshwater mollusc Hyriopsis cumingii (Zhejiang province, China) were chosen to analyze microstructure…”
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A Novel Resorbable Embolization Microsphere for Transient Uterine Artery Occlusion: A Comparative Study with Trisacryl-Gelatin Microspheres in the Sheep Model by Verret, Valentin, Eng MSc, Pelage, Jean Pierre, MD, Wassef, Michel, MD, Louguet, Stéphanie, PhD, Servais, Emeline, PhD, Bédouet, Laurent, PhD, Beaulieu, Thomas, Eng MSc, Moine, Laurence, PhD, Laurent, Alexandre, MD, PhD

“…Abstract Purpose To evaluate angiographic recanalization, inflammatory reaction, and uterine damage after sheep uterine artery embolization (UAE) with a novel…”
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Heterogeneity of Proteinase Inhibitors in the Water-Soluble Organic Matrix from the Oyster Nacre by Bédouet, Laurent, Duplat, Denis, Marie, Arul, Dubost, Lionel, Berland, Sophie, Rousseau, Marthe, Milet, Christian, Lopez, Evelyne

“…We extracted proteinase inhibitors from the nacre of the oyster Pinctada margaritifera with water. Mixing the nacre powder with water for 20 h led to a…”
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Soil calcium availability influences shell ecophenotype formation in the sub-antarctic land snail, Notodiscus hookeri by Charrier, Maryvonne, Marie, Arul, Guillaume, Damien, Bédouet, Laurent, Le Lannic, Joseph, Roiland, Claire, Berland, Sophie, Pierre, Jean-Sébastien, Le Floch, Marie, Frenot, Yves, Lebouvier, Marc

“…Ecophenotypes reflect local matches between organisms and their environment, and show plasticity across generations in response to current living conditions…”
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