Search Results - "Bednarz, Iwona"
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Atherogenic Plasma Index or Non-High-Density Lipoproteins as Markers Best Reflecting Age-Related High Concentrations of Small Dense Low-Density Lipoproteins
Published in International journal of molecular sciences (03-05-2022)“…The study aimed to assess the strength of the relationships between small dense low-density lipoproteins (sdLDL) and other parameters describing metabolic…”
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2
Transcriptional and Metabolomic Analysis of L-Arginine/Nitric Oxide Pathway in Inflammatory Bowel Disease and Its Association with Local Inflammatory and Angiogenic Response: Preliminary Findings
Published in International journal of molecular sciences (28-02-2020)“…L-arginine/nitric oxide pathway in Crohn's disease (CD) and ulcerative colitis (UC) is poorly investigated. The aim of current study is to quantify pathway…”
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3
Distinct Local and Systemic Molecular Signatures in the Esophageal and Gastric Cancers: Possible Therapy Targets and Biomarkers for Gastric Cancer
Published in International journal of molecular sciences (25-06-2020)“…Gastric (GC) and esophageal (EC) cancers are highly lethal. Better understanding of molecular abnormalities is needed for new therapeutic targets and…”
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4
Systemic interleukin-9 in inflammatory bowel disease: Association with mucosal healing in ulcerative colitis
Published in World journal of gastroenterology : WJG (14-06-2017)“…AIM To evaluate circulating IL9 in inflammatory bowel disease and disease-associated anemia/cachexia and assess its potential as a mucosal healing…”
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5
Cornelian Cherry (Cornus mas L.) Extracts Exert Cytotoxicity in Two Selected Melanoma Cell Lines—A Factorial Analysis of Time-Dependent Alterations in Values Obtained with SRB and MTT Assays
Published in Molecules (Basel, Switzerland) (29-06-2022)“…Despite the fact that phytochemicals of Cornaceae species have long been discussed as possible auxiliary agents in contemporary treatment, the insights on…”
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Local and Systemic IL-7 Concentration in Gastrointestinal-Tract Cancers
Published in Medicina (Kaunas, Lithuania) (10-06-2019)“…Interleukin-7 (IL-7) is exploited in cancer immunotherapies although its status in solid tumors is largely unknown. We aimed to determine its systemic and…”
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Cornus mas L. Extract Targets the Specific Molecules of the Th17/Treg Developmental Pathway in TNBS-Induced Experimental Colitis in Rats
Published in Molecules (Basel, Switzerland) (29-03-2023)“…Given that one of the crucial events in the pathogenesis of inflammatory bowel disease is the loss of homeostasis between Th17 and Treg cells, targeting the…”
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Macrophage Inflammatory Proteins (MIPs) Contribute to Malignant Potential of Colorectal Polyps and Modulate Likelihood of Cancerization Associated with Standard Risk Factors
Published in International journal of molecular sciences (01-02-2024)“…Better understanding of molecular changes leading to neoplastic transformation is prerequisite to optimize risk assessment and chemopreventive and surveillance…”
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Nampt/PBEF/visfatin upregulation in colorectal tumors, mirrored in normal tissue and whole blood of colorectal cancer patients, is associated with metastasis, hypoxia, IL1[beta], and anemia
Published in BioMed research international (01-01-2015)“…Targeting Nampt/PBEF/visfatin is considered a promising anticancer strategy, yet little is known about its association with colorectal cancer (CRC). We…”
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Nampt/PBEF/Visfatin Upregulation in Colorectal Tumors, Mirrored in Normal Tissue and Whole Blood of Colorectal Cancer Patients, Is Associated with Metastasis, Hypoxia, IL1β, and Anemia
Published in BioMed research international (01-01-2015)“…Targeting Nampt/PBEF/visfatin is considered a promising anticancer strategy, yet little is known about its association with colorectal cancer (CRC). We…”
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Modulating Properties of Piroxicam, Meloxicam and Oxicam Analogues against Macrophage-Associated Chemokines in Colorectal Cancer
Published in Molecules (Basel, Switzerland) (05-12-2021)“…The mechanisms underlying the antineoplastic effects of oxicams have not been fully elucidated. We aimed to assess the effect of classic and novel oxicams on…”
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Biochemical and Molecular Investigation of the Effect of Saponins and Terpenoids Derived from Leaves of Ilex aquifolium on Lipid Metabolism of Obese Zucker Rats
Published in Molecules (Basel, Switzerland) (24-05-2022)“…Ilex paraguariensis, the holly tree, is a plant with recognized biological properties, whose aqueous infusions are known as “Yerba mate”, that regulate lipid…”
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13
Nonenzymatic Serum Antioxidant Capacity in IBD and Its Association with the Severity of Bowel Inflammation and Corticosteroids Treatment
Published in Medicina (Kaunas, Lithuania) (02-04-2019)“…: Oxidative stress signalling plays a monumental role in inflammatory bowel disease (IBD). Reduction of oxidative stress might control inflammation, block…”
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14
Klebsiella pneumoniae enolase-like membrane protein interacts with human plasminogen
Published in International journal of medical microbiology (01-08-2021)“…Many models assessing the risk of sepsis utilize the knowledge of the constituents of the plasminogen system, as it is proven that some species of bacteria can…”
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Esophageal Squamous Cell Carcinoma Is Accompanied by Local and Systemic Changes in L-arginine/NO Pathway
Published in International journal of molecular sciences (30-08-2020)“…The L-arginine/NO pathway holds promise as a source of potential therapy target and biomarker; yet, its status and utility in esophageal squamous cell…”
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Altered L-Arginine Metabolic Pathways in Gastric Cancer: Potential Therapeutic Targets and Biomarkers
Published in Biomolecules (Basel, Switzerland) (23-07-2021)“…There is a pressing need for molecular targets and biomarkers in gastric cancer (GC). We aimed at identifying aberrations in L-arginine metabolism with…”
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Experimental and bioinformatic approach to identifying antigenic epitopes in human α- and β-enolases
Published in Biochemistry and biophysics reports (01-09-2018)“…Human α- and β-enolases are highly homologous enzymes, difficult to differentiate immunologically. In this work, we describe production, purification and…”
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Diagnostic Potential of Systemic Eosinophil-Associated Cytokines and Growth Factors in IBD
Published in Gastroenterology research and practice (01-01-2018)“…Despite the acknowledged contribution of eosinophils to the disease pathogenesis, available data on cytokines closely related to the peripheral eosinophils in…”
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Oxidative modulation of marcaine and lekoptin in H9C2 rat myoblasts
Published in Acta pharmacologica Sinica (01-02-2009)“…Aim: The cytotoxicity of marcaine was estimated in combination with a calcium channel blocker. In addition, the influence of marcaine and marcaine plus…”
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Circulating adipocyte fatty acid-binding protein, juvenile obesity, and metabolic syndrome
Published in Journal of pediatric endocrinology & metabolism : JPEM (2011)“…Adipocyte fatty acid-binding protein (A-FABP) links obesity and metabolic syndrome (MetS) and might be targeted in future therapies. Its utility as a MetS…”
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