Search Results - "Bednar, R."

Low back pain in patients hospitalised with liver cirrhosis- a retrospective study by Bednár, R, Líška, D, Gurín, D, Vnenčaková, J, Melichová, A, Koller, T, Skladaný, Ľ

“…Lower back pain is a common issue, but little is known about the prevalence of pain in patients with liver cirrhosis during hospitalisation. Therefore, the…”
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Directing Substrate Morphology via Self-Assembly: Ligand-Mediated Scission of Gallium–Indium Microspheres to the Nanoscale by Hohman, J. Nathan, Kim, Moonhee, Wadsworth, Garrett A, Bednar, Heidi R, Jiang, Jun, LeThai, Mya A, Weiss, Paul S

“…We have developed a facile method for the construction of liquid-phase eutectic gallium–indium (EGaIn) alloy nanoparticles. Particle formation is directed by…”
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Subtractive Patterning via Chemical Lift-Off Lithography by Liao, Wei-Ssu, Cheunkar, Sarawut, Cao, Huan H., Bednar, Heidi R., Weiss, Paul S., Andrews, Anne M.

“…Conventional soft-lithography methods involving the transfer of molecular "inks" from polymeric stamps to substrates often encounter micrometer-scale…”
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Investigations of the Mechanism of Gold Nanoparticle Stability and Surface Functionalization in Capillary Electrophoresis by Ivanov, Michael R, Bednar, Heidi R, Haes, Amanda J

“…Covalently functionalized gold nanoparticles influence capillary electrophoresis separations of neurotransmitters in a concentration- and…”
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The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents by Hutson, P H, Finger, E N, Magliaro, B C, Smith, S M, Converso, A, Sanderson, P E, Mullins, D, Hyde, L A, Eschle, B K, Turnbull, Z, Sloan, H, Guzzi, M, Zhang, X, Wang, A, Rindgen, D, Mazzola, R, Vivian, J A, Eddins, D, Uslaner, J M, Bednar, R, Gambone, C, Le-Mair, W, Marino, M J, Sachs, N, Xu, G, Parmentier-Batteur, S

“…Inhibition of phosphodiesterase 9 (PDE9) has been reported to enhance rodent cognitive function and may represent a potential novel approach to improving…”
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Allelic loss at the D9S171 locus on chromosome 9p13 is associated with progression of papillary renal cell carcinoma by Schraml, P., Müller, D., Bednar, R., Gasser, Th, Sauter, G., Mihatsch, M. J., Moch, H.

“…Papillary renal cell carcinomas (RCCs) have characteristic clinical and morphological features that separate them from the more common clear cell RCCs. The…”
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CDKN2A Mutation Analysis, Protein Expression, and Deletion Mapping of Chromosome 9p in Conventional Clear-Cell Renal Carcinomas : Evidence for a Second Tumor Suppressor Gene Proximal to CDKN2A by Schraml, Peter, Struckmann, Kirsten, Bednar, Rudolf, Fu, Wenting, Gasser, Thomas, Wilber, Kim, Kononen, Juha, Sauter, Guido, Mihatsch, Michael J, Moch, Holger

“…Inactivation of tumor suppressor genes on chromosome 9p is considered a critical event in renal cell carcinoma pathogenesis. Alterations of CDKN2A on 9p21 have…”
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Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb/IIIa by BEDNAR, B, COOK, J. J, HOLAHAN, M. A, CUNNINGHAM, M. E, JUMES, P. A, BEDNAR, R. A, HARTMAN, G. D, GOULD, R. J

“…Most clinical trials with fibrinogen receptor antagonists (FRAs) have been associated with thrombocytopenia. This report describes the occurrence of…”
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Non-Peptide GPIIb/IIIa Inhibitors. 20. Centrally Constrained Thienothiophene α-Sulfonamides Are Potent, Long Acting in Vivo Inhibitors of Platelet Aggregation by Egbertson, Melissa S, Cook, Jacquelynn J, Bednar, Bohumil, Prugh, John D, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Hartman, George D, Homnick, Carl F, Holahan, Marie A, Libby, Laura A, Lynch, Joseph J, Lynch, Robert J, Sitko, Gary R, Stranieri, Maria T, Vassallo, Laura M

“…The synthesis and pharmacology of 4, a potent thienothiophene non-peptide fibrinogen receptor antagonist, are reported. Compound 4 inhibited the aggregation of…”
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Reactivity and pH dependence of thiol conjugation to N-ethylmaleimide: detection of a conformational change in chalcone isomerase by Bednar, Rodney A

“…The reactivity of simple alkyl thiolates with N-ethylmaleimide (NEM) follows the Brønsted equation, log kS- = log G + beta pK, with G = 790 M-1 min-1 and beta…”
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Managing power and performance for System-on-Chip designs using Voltage Islands by Lackey, David E., Zuchowski, Paul S., Bednar, Thomas R., Stout, Douglas W., Gould, Scott W., Cohn, John M.

“…This paper discusses Voltage Islands, a system architecture and chip implementation methodology, that can be used to dramatically reduce active and static…”
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Lupus anticoagulant and venous leg ulceration by Fink, A.M., Kottas-Heldenberg, A., Mayer, W., Partsch, H., Bayer, P.M., Bednar, R., Steiner, A.

“…Summary Background  Most leg ulcers occur in patients with venous insufficiency. However, not all patients with venous insufficiency develop leg ulcers. Recent…”
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Kinetic analysis of the inhibition of the epidermal growth factor receptor tyrosine kinase by Lavendustin-A and its analogue by Hsu, C.Y., Persons, P.E., Spada, A.P., Bednar, R.A., Levitzki, A., Zilberstein, A.

“…Lavendustin-A was reported to be a potent tyrosine kinase inhibitor of the epidermal growth factor (EGF) receptor (Onoda, T., Iinuma, H., Sasaki, Y., Hamada,…”
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A comparative study of frictional forces between orthodontic brackets and arch wires by Bednar, James R., Gruendeman, Gary W., Sandrik, James L.

“…An in vitro study of simulated canine retraction was undertaken to evaluate the difference in frictional resistance between stainless steel arch wires and…”
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Purification and characterization of chalcone isomerase from soybeans by Bednar, R A, Hadcock, J R

“…Chalcone isomerase from soybean has been purified 11,000-fold over the crude extract. The purification procedure features pseudo-affinity chromatography on an…”
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Non-Peptide Glycoprotein IIb/IIIa Inhibitors. 17. Design and Synthesis of Orally Active, Long-Acting Non-Peptide Fibrinogen Receptor Antagonists by Askew, Benny C, Bednar, Rodney A, Bednar, Bohumil, Claremon, David A, Cook, Jacquelynn J, McIntyre, Charles J, Hunt, Cecila A, Gould, Robert J, Lynch, Robert J, Lynch, Joseph J, Gaul, Stanley L, Stranieri, Maria T, Sitko, Gary R, Holahan, Marie A, Glass, Joan D, Hamill, Terrence, Gorham, Lynn M, Prueksaritanont, Thomayant, Baldwin, John J, Hartman, George D

“…The synthesis and pharmacological evaluation of 5 (L-738,167), a potent, selective non-peptide fibrinogen receptor antagonist is reported. Compound 5 inhibited…”
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In vitro characterization of novel NR2B selective NMDA receptor antagonists by Kiss, Laszlo, Cheng, Gong, Bednar, Bohumil, Bednar, Rodney A., Bennett, Paul B., Kane, Stefanie A., McIntyre, Charles J., McCauley, John A., Koblan, Kenneth S.

“…N-Methyl- d-aspartate (NMDA) subunit specific receptor antagonism has potential therapeutic application for multiple CNS pathologies. MERCK 1, MERCK 2, and…”
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Identification and characterization of endothelin converting activity from EAHY 926 cells: evidence for the physiologically relevant human enzyme by Waxman, L, Doshi, K P, Gaul, S L, Wang, S, Bednar, R A, Stern, A M

“…A neutral proteolytic activity that converts human Big endothelin-1 (Big Et-1) to endothelin-1 has been identified from a human endothelial hybrid cell line,…”
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Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors by Egbertson, Melissa S, Bednar, Bohumil, Askew, Ben C, Bednar, Rodney A, Brashear, Karen, Breslin, Michael J, Duggan, Mark E, Fisher, Thorsten E, Halczenko, Wasyl, Hutchinson, John H, Ihle, Nathan, Prugh, John D, Wai, John S, Gould, Robert J, Hartman, George D

“…Compound affinity for activated and resting GPIIb/IIIa receptors may differ, and comparison of those differences determines selectivity. Structural features…”
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Chemical modification of chalcone isomerase by mercurials and tetrathionate. Evidence for a single cysteine residue in the active site by BEDNAR, R. A, FRIED, W. B, LOCK, Y. W, BARNALI PRAMANIK

“…Chalcone isomerase from soybean is inactivated by stoichiometric amounts of p-mercuribenzoate or HgCl2. Spectral titration of the enzyme with p-mercuribenzoate…”
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