Search Results - "Bedman, Timothy"

Genotoxicity evaluation of a valsartan-related complex N-nitroso-impurity by Glowienke, Susanne, Onken, Ulrich, Elhajouji, Azeddine, Muthusamy, Sasikumar, Sangana, Ramachandra, Martus, Hans-Joerg, Bedman, Timothy, Hartmann, Andreas

“…Recently, the formation of genotoxic and carcinogenic N-nitrosamines impurities during drug manufacturing of tetrazole-containing angiotensin-II blockers has…”
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Disposition and metabolism of [14C] Sacubitril/Valsartan (formerly LCZ696) an angiotensin receptor neprilysin inhibitor, in healthy subjects by Flarakos, Jimmy, Du, Yancy, Bedman, Timothy, Al-Share, Qusai, Jordaan, Pierre, Chandra, Priya, Albrecht, Diego, Wang, Lai, Gu, Helen, Einolf, Heidi J., Huskey, Su-Er, Mangold, James B.

“…1. Sacubitril/valsartan (LCZ696) is an angiotensin receptor neprilysin inhibitor (ARNI) providing simultaneous inhibition of neprilysin (neutral endopeptidase…”
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