Search Results - "Bedin, Monique"
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Ligand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells
Published in BMC cancer (16-07-2012)“…Ligand-dependent activation of the estrogen receptor (ER) as well as of the insulin-like growth factor type 1 (IGF1R) induces the proliferation of luminal…”
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The c-kit tyrosine kinase inhibitor STI571 for colorectal cancer therapy
Published in Cancer research (Chicago, Ill.) (01-09-2002)“…The c-kit tyrosine kinase inhibitor STI571 exhibits a substantial therapeutic activity in patients with chronic myeloid leukemia and gastrointestinal stromal…”
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Geldanamycin, an inhibitor of the chaperone activity of HSP90, induces MAPK‐independent cell cycle arrest
Published in International journal of cancer (01-05-2004)“…The effects of GA, an ansamycin antibiotic in development as a lead anticancer drug, were studied in mouse BP‐A31 fibroblasts and in human cancer‐derived cell…”
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Indirect participation of Hsp90 in the regulation of the cyclin E turnover
Published in Biochemical pharmacology (15-01-2009)“…Cyclin E is the Cdk2-regulatory subunit required for the initiation of DNA replication at the G1/S transition. It accumulates in late G1 phase and gets rapidly…”
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Mitogenic Activity of Estrogens in Human Breast Cancer Cells Does Not Rely on Direct Induction of Mitogen-Activated Protein Kinase/Extracellularly Regulated Kinase or Phosphatidylinositol 3-Kinase
Published in Molecular endocrinology (Baltimore, Md.) (01-11-2004)“…We have addressed the question of rapid, nongenomic mechanisms that may be involved in the mitogenic action of estrogens in hormone-dependent breast cancer…”
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Rapamycin inhibits cdk4 activation, p 21(WAF1/CIP1) expression and G1-phase progression in transformed mouse fibroblasts
Published in International journal of cancer (10-01-2004)“…Rapamycin, a bacterial macrolide antibiotic, is a potent immunosuppressant agent that blocks cell proliferation by inhibiting the G1/S transition in several…”
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Rapamycin inhibits cdk4 activation, p 21WAF1/CIP1 expression and G1‐phase progression in transformed mouse fibroblasts
Published in International journal of cancer (10-01-2004)“…Rapamycin, a bacterial macrolide antibiotic, is a potent immunosuppressant agent that blocks cell proliferation by inhibiting the G1/S transition in several…”
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Rapamycin inhibits cdk4 activation, p 21 WAF1/CIP1 expression and G1‐phase progression in transformed mouse fibroblasts
Published in International journal of cancer (10-01-2004)“…Rapamycin, a bacterial macrolide antibiotic, is a potent immunosuppressant agent that blocks cell proliferation by inhibiting the G1/S transition in several…”
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Testicular steroid sulfatase in a cryptorchid rat strain
Published in Journal of steroid biochemistry (1989)“…Steroid sulfatase (STS) activity was studied in scrotal and abdominal testes from genetically unilateral cryptorchid rats. Specific STS activity was…”
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Biochemical evidence for the non-inactivation of the steroid sulfatase locus in human placenta and fibroblasts
Published in Human genetics (01-01-1981)“…Steroid sulfatase activities are significantly higher in placentas obtained after the birth of girls than after the birth of boys, and also in female…”
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Incidence of placental sulfatase deficiency on the mode of termination of pregnancy
Published in Gynecologic and obstetric investigation (01-01-1987)“…The mode of termination of pregnancy in case of placental sulfatase deficiency (PSD) has been considered in a 28-case series from our laboratory. After…”
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Ontogenesis and regulation of steroid sulfatase activity in Leydig cells and seminiferous tubules in the Long-Evans rat
Published in Journal of steroid biochemistry (1988)“…Steroid sulfatase (STS) activity was studied in Long-Evans rat testis. The affinity of the enzyme was shown to increase during postnatal development and to be…”
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