Search Results - "Bedi, P.M.S."

Development and characterization of a novel controlled release drug delivery system based on nanostructured lipid carriers gel for meloxicam by Khurana, S., Jain, N.K., Bedi, P.M.S.

“…The main objective of the current investigation was to develop nanostructured lipid carriers (NLC) based gel for the enhancement of transdermal absorption of…”
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Nanoemulsion based gel for transdermal delivery of meloxicam: Physico-chemical, mechanistic investigation by Khurana, S., Jain, N.K., Bedi, P.M.S.

“…The aim of the present investigation was to develop a nanoemulsion (NE) gel formulation for the transdermal delivery of meloxicam (MLX) in order to ensure…”
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Preparation and evaluation of solid lipid nanoparticles based nanogel for dermal delivery of meloxicam by Khurana, S., Bedi, P.M.S., Jain, N.K.

“…•We prepared solid lipid nanoparticles based gel for dermal delivery of meloxicam.•The experiments were focused on the inflamed tissue and the skin…”
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Synthesis and in vitro cytotoxic evaluation of N-alkylbromo and N-alkylphthalimido-isatins by Singh, Pardeep, Kaur, Sharanjeet, Kumar, Vipan, Bedi, P.M.S., Mahajan, M.P., Sehar, Irum, Pal, Harish Chandra, Saxena, Ajit Kumar

“…The manuscript pertains to the synthesis and in vitro cytotoxic evaluation of a series of N-alkylbromo and N-alkylphthalimido-isatins against four different…”
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Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids by Nepali, Kunal, Sharma, Sahil, Sharma, Manmohan, Bedi, P.M.S., Dhar, K.L.

“…A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single molecule are basically designed to interact with multiple targets or…”
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Synthesis and evaluation of naphthoflavones as a new class of non purine xanthine oxidase inhibitors by Singh, Harbinder, Sharma, Sahil, Ojha, Ritu, Gupta, Manish K., Nepali, Kunal, Bedi, P.M.S.

“…•Design of naphthoflavones.•Synthesis and characterization of naphthoflavone.•In vitro xanthine oxidase assay.•Enzyme kinetics study.•Molecular modeling study…”
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1,2,3-Triazole tethered β-lactam-Chalcone bifunctional hybrids: Synthesis and anticancer evaluation by Singh, Pardeep, Raj, Raghu, Kumar, Vipan, Mahajan, Mohinder P., Bedi, P.M.S., Kaur, Tandeep, Saxena, A.K.

“…The manuscript describes the synthesis of novel 1,2,3-triazole tethered β-lactam-chalcone bifunctional hybrids via click chemistry approach utilizing…”
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Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors by Sharma, Sahil, Sharma, Kirti, Ojha, Ritu, Kumar, Dinesh, Singh, Gagandip, Nepali, Kunal, Bedi, P.M.S.

“…A series of naphthopyrans was synthesized employing silica supported fluoroboric acid under solvent free conditions in a microwave reactor. The catalytic…”
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Design strategies, structure activity relationship and mechanistic insights for purines as kinase inhibitors by Sharma, Sahil, Singh, Jagjeet, Ojha, Ritu, Singh, Harbinder, Kaur, Manpreet, Bedi, P.M.S., Nepali, Kunal

“…Kinases control a diverse set of cellular processes comprising of reversible phosphorylation of proteins. Protein kinases play a pivotal role in human tumor…”
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Azide-alkyne cycloaddition en route to novel 1H-1,2,3-triazole tethered isatin conjugates with in vitro cytotoxic evaluation by Singh, Pardeep, Sharma, Pooja, Anand, Amit, Bedi, P.M.S., Kaur, Tandeep, Saxena, A.K., Kumar, Vipan

“…1H-1,2,3-triazole tethered isatin conjugates have been synthesized and evaluated for cytotoxicity on four human cancer cell lines. The results revealed 5a, 5c,…”
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Chalcone based azacarboline analogues as novel antitubulin agents: Design, synthesis, biological evaluation and molecular modelling studies by Sharma, Sahil, Kaur, Charanjit, Budhiraja, Abhishek, Nepali, Kunal, Gupta, Manish K., Saxena, A.K., Bedi, P.M.S.

“…The present study involves the design of a series of 3-aryl-9-acetyl-pyridazino[3,4-b]indoles as constrained chalcone analogues. A retrosynthetic route was…”
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