Search Results - "Bedford, S J"

From DNA damage to chromosome aberrations: Joining the break by Durante, M., Bedford, J.S., Chen, D.J., Conrad, S., Cornforth, M.N., Natarajan, A.T., van Gent, D.C., Obe, G.

“…Despite many years of experimental studies on radiation-induced chromosomal aberrations, and the recent progress in elucidating the molecular mechanisms of the…”
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Premature luteal regression in a pregnant mare and subsequent pregnancy maintenance with the use of oral altrenogest by CANISSO, I. F., BELTAIRE, K. A., BEDFORD‐GUAUS, S. J.

“…Summary Premature luteal demise or luteal insufficiency is not well characterised as a cause of pregnancy loss in domestic species, including horses. In this…”
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A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse by Okayasu, R., Suetomi, K., Yu, Y., Silver, A., Bedford, J. S., Cox, R., Ullrich, R. L.

“…We have studied the efficiency of DNA double strand break (DSB) rejoining in primary cells from mouse strains that show large differences in in vivo…”
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Molecular markers of putative spermatogonial stem cells in the domestic cat by Bedford‐Guaus, SJ, Kim, S, Mulero, L, Vaquero, JM, Morera, C, Adan‐Milanès, R, Veiga, A, Raya, Á

“…Contents Spermatogonial stem cells (SSCs) are an important tool for fertility preservation and species conservation. The ability to expand SSCs by in vitro…”
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Role of Homologous Recombination in the Alpha-Particle-Induced Bystander Effect for Sister Chromatid Exchanges and Chromosomal Aberrations by Nagasawa, H., Peng, Y., Wilson, P. F., Lio, Y-C., Chen, D. J., Bedford, J. S., Little, J. B.

“…Nagasawa, H., Peng, Y., Wilson, P. F., Lio, Y-C., Chen, D. J., Bedford, J. S. and Little, J. B. Role of Homologous Recombination in the Alpha-Particle-Induced…”
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Molecular Cloning and Characterization of Phospholipase C Zeta in Equine Sperm and Testis Reveals Species-Specific Differences in Expression of Catalytically Active Protein by BEDFORD-GUAUS, S. J, MCPARTLIN, L. A, XIE, J, WESTMILLER, S. L, BUFFONE, M. G, ROBERSON, M. S

“…Oocyte activation at fertilization is brought about by the testis-specific phospholipase C zeta (PLCZ), owing to its ability to induce oscillations in…”
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Discontinuous Order Parameters in Liquid Crystal Theories by Ball, J. M., Bedford, S. J.

“…The paper is concerned with various issues surrounding the mathematical description of defects in models of liquid crystals, drawing on experience from solid…”
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Intracellular calcium oscillations and activation in horse oocytes injected with stallion sperm extracts or spermatozoa by Bedford, SJ, Kurokawa, M, Hinrichs, K, Fissore, RA

“…In oocytes from all mammalian species studied to date, fertilization by a spermatozoon induces intracellular calcium ([Ca(2+)](i)) oscillations that are…”
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Guanine-Nucleotide Exchange Factors (RAPGEF3/RAPGEF4) Induce Sperm Membrane Depolarization and Acrosomal Exocytosis in Capacitated Stallion Sperm by MCPARTLIN, L. A, VISCONTI, P. E, BEDFORD-GUAUS, S. J

“…Capacitation encompasses the molecular changes sperm undergo to fertilize an oocyte, some of which are postulated to occur via a cAMP-PRKACA (protein kinase…”
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Sublethal damage, potentially lethal damage, and chromosomal aberrations in mammalian cells exposed to ionizing radiations by Bedford, J S

“…Sublethal and potentially lethal damage are abstract terms that originated and were defined without reference to molecular and subcellular entities in which…”
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Effects of Radiation on the Environment: A Need to Question Old Paradigms and Enhance Collaboration among Radiation Biologists and Radiation Ecologists by Hinton, T. G., Bedford, J. S., Congdon, J. C., Whicker, F. W.

“…Hinton, T. G., Bedford, J. S., Congdon, J. C. and Whicker, F. W. Effects of Radiation on the Environment: A Need to Question Old Paradigms and Enhance…”
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A Quantitative Comparison of Potentially Lethal Damage Repair and the Rejoining of Interphase Chromosome Breaks in Low Passage Normal Human Fibroblasts by Cornforth, Michael N., Bedford, Joel S.

“…After long postirradiation incubation periods, the residual frequency of prematurely condensed chromosome fragments following X-ray exposure of noncycling…”
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Levels of γ-H2AX Foci after Low-Dose-Rate Irradiation Reveal a DNA DSB Rejoining Defect in Cells from Human ATM Heterozygotes in Two AT Families and in Another Apparently Normal Individual by Kato, Takamitsu A., Nagasawa, Hatsumi, Weil, Michael M., Little, J. B., Bedford, J. S.

“…Kato, T. A., Nagasawa, H., Weil, M. M., Little, J. B. and Bedford, J. S. Levels of γ-H2AX Foci after Low-Dose-Rate Irradiation Reveal a DNA DSB Rejoining…”
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Chromosome Translocations in Turtles: A Biomarker in a Sentinel Animal for Ecological Dosimetry by Ulsh, B. A., Mühlmann-Díaz, M. C., Whicker, F. W., Hinton, T. G., Congdon, J. D., S. Bedford, J.

“…Ulsh, B. A., Mühlmann-Díaz, M. C., Whicker, F. W., Hinton, T. G., Congdon, J. D. and Bedford, J. S. Chromosome Translocations in Turtles: A Biomarker in a…”
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Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20 by Priestley, A., Beamish, H.J., Singleton, B.K., Blunt, T., Jeggo, P.A., Gell, D., Smith, G.C.M., Jackson, S.P., Amatucci, A.G., Taccioli, G.E., Muhlmann-Diaz, M.C., Bedford, J.S., Schalkwyk, L.C.

“…The catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs) is a member of a sub-family of phosphatidylinositol (PI) 3-kinases termed PIK-related…”
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Chromosome Translocations in T. scripta: The Dose-Rate Effect and In Vivo Lymphocyte Radiation Response by Ulsh, B. A., Whicker, F. W., Hinton, T. G., Congdon, J. D., Bedford, J. S.

“…Ulsh, B. A., Whicker, F. W., Hinton, T. G., Congdon, J. D. and Bedford, J. S. Chromosome Translocations in T. scripta: The Dose-Rate Effect and In Vivo…”
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An Ionizing Radiation-Sensitive Mutant of CHO Cells: irs-20: II. Dose-Rate Effects and Cellular Recovery Processes by Stackhouse, M. A., Bedford, J. S.

“…An ionizing radiation-sensitive mutant of CHO cells, irs-20, irradiated in plateau-phase cultures showed a complete lack of a dose-rate effect, i.e., there was…”
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Influence of plant development and environment on transgene expression in potato and consequences for insect resistance by DOWN, Rachel E, FORD, Louise, BEDFORD, Simon J, GATEHOUSE, Laurence N, NEWELL, Christine, GATEHOUSE, John A, GATEHOUSE, Angharad M. R

“…Clonal replicates of different transformed potato plants expressing transgene constructs containing the constitutive Cauliflower Mosaic Virus (CaMV) 35S…”
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An Ionizing Radiation-Sensitive Mutant of CHO Cells: irs-20: I. Isolation and Initial Characterization by Stackhouse, M. A., Bedford, J. S.

“…We have isolated a stable mutant of CHO cells, designated irs-20, that is hypersensitive to ionizing radiation. The selection system was designed to select for…”
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Comparison of Gamma-Ray-Induced Chromosome Ring and Inversion Frequencies by Mühlmann-Díaz, María C., Bedford, Joel S.

“…A method was used to detect chromosome inversions as apparent or false sister chromatid exchanges (SCEs) in the first mitosis after γ irradiation of human G0…”
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