Search Results - "Bedford, Guy"
-
1
Discovery of 4,4′-Dipyridylsulfide Analogs as “Switchable Electrophiles” for Covalent Inhibition
Published in ACS chemical biology (19-02-2021)“…Electrophilic heterocycles offer attractive features as covalent fragments for inhibitor and probe development. A focused library of heterocycles for which…”
Get full text
Journal Article -
2
Persistent tailoring of MSC activation through genetic priming
Published in Molecular therapy. Methods & clinical development (12-09-2024)“…Mesenchymal stem/stromal cells (MSCs) are an attractive platform for cell therapy due to their safety profile and unique ability to secrete broad arrays of…”
Get full text
Journal Article -
3
Resting Metabolic Rate and Lung Function in Wild Offshore Common Bottlenose Dolphins, Tursiops truncatus , Near Bermuda
Published in Frontiers in physiology (17-07-2018)“…Diving mammals have evolved a suite of physiological adaptations to manage respiratory gases during extended breath-hold dives. To test the hypothesis that…”
Get full text
Journal Article -
4
Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control
Published in Nature methods (01-11-2023)“…Engineered transactivation domains (TADs) combined with programmable DNA binding platforms have revolutionized synthetic transcriptional control. Despite…”
Get full text
Journal Article -
5
Adapting dugong catching techniques to different cultural and environmental settings
Published in Marine mammal science (01-01-2013)Get full text
Journal Article -
6