Search Results - "Bedell, Mary A."

A molecular basis for classic blond hair color in Europeans by Guenther, Catherine A, Tasic, Bosiljka, Luo, Liqun, Bedell, Mary A, Kingsley, David M

“…David Kingsley and colleagues functionally investigate a previously identified GWAS region in an enhancer of the KITLG gene (encoding KIT ligand) that is…”
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CD40 Ligand Gene Defects Responsible for X-Linked Hyper-IgM Syndrome by Allen, R. Cutler, Armitage, Richard J., Conley, Mary Ellen, Rosenblatt, Howard, Jenkins, Nancy A., Copeland, Neal G., Bedell, Mary A., Edelhoff, Susanne, Disteche, Christine M., Simoneaux, Denise K., Fanslow, William C., Belmont, John, Spriggs, Melanie K.

“…The ligand for CD40 (CD40L) is a membrane glycoprotein on activated T cells that induces B cell proliferation and immunoglobulin secretion. Abnormalities in…”
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Analysis of Hypomorphic KitlSl Mutants Suggests Different Requirements for KITL in Proliferation and Migration of Mouse Primordial Germ Cells1 by Mahakali Zama, Aparna, Hudson, III, F. Parker, Bedell, Mary A

“…Germ cell development in mice is initiated when a small number of primordial germ cells (PGCs) are set aside from somatic cells during gastrulation. In the…”
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Molecular cloning and biological characterization of a novel murine lymphoid growth factor by Sims, J E, Williams, D E, Morrissey, P J, Garka, K, Foxworthe, D, Price, V, Friend, S L, Farr, A, Bedell, M A, Jenkins, N A, Copeland, N G, Grabstein, K, Paxton, R J

“…Using a bioassay consisting of the proliferation of a murine B cell line, a cDNA of a gene whose product supports the growth of that cell line was isolated…”
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Good genes in bad neighbourhoods by Bedell, Mary A, Jenkins, Nancy A, Copeland, Neal G

“…Recent advances in genome research have spawned a dramatic explosion in positional cloning experiments. A good example is reported on page 260 of this issue of…”
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Analysis of Hypomorphic KitlSl Mutants Suggests Different Requirements for KITL in Proliferation and Migration of Mouse Primordial Germ Cells by Mahakali Zama, Aparna, Hudson, 3rd, F Parker, Bedell, Mary A

“…Germ cell development in mice is initiated when a small number of primordial germ cells (PGCs) are set aside from somatic cells during gastrulation. In the…”
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Genetic Analysis of Kit Ligand Functions During Mouse Spermatogenesis by Bedell, Mary A., Zama, Aparna Mahakali

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Effects of spontaneous Kitl Steel mutations on survival and red blood cells of mice by Rajaraman, Sripriya, Wood, Lawrence K., Willhite, Dorian K., Russell, Liane B., Bedell, Mary A.

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Multiple pathways for Steel regulation suggested by genomic and sequence analysis of the murine Steel gene by Bedell, M A, Copeland, N G, Jenkins, N A

“…The Steel (Sl) locus encodes mast cell growth factor (Mgf) that is required for the development of germ cells, hematopoietic cells and melanocytes. Although…”
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Deletion and Interallelic Complementation Analysis of Steel Mutant Mice by Bedell, M. A, Cleveland, L. S, O'Sullivan, T. N, Copeland, N. G, Jenkins, N. A

“…Mutations at the Steel (Sl) locus produce pleiotropic effects on viability as well as hematopoiesis, pigmentation and fertility. Several homozygous viable Sl…”
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Mouse models of human disease. Part II: recent progress and future directions by Bedell, M A, Largaespada, D A, Jenkins, N A, Copeland, N G

“…The development of new methods for manipulating the mouse genome, including transgenic and embryonic stem (ES) cell knockout technology, combined with greatly…”
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Analysis of hypomorphic Kitlsi mutants suggests different requirements for KITL in proliferation and migration of mouse primordial germ cells by ZAMA, Aparna Mahakali, HUDSON, F. Parker, BEDELL, Mary A

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Mouse models of human disease. Part I: techniques and resources for genetic analysis in mice by Bedell, M A, Jenkins, N A, Copeland, N G

“…The mouse is an ideal model organism for human disease. Not only are mice physiologically similar to humans, but a large genetic reservoir of potential models…”
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Effect of chronic ethanol diet on the replication, alkylation, and repair of DNA from hepatocytes and nonparenchymal cells following dimethylnitrosamine administration by Belinsky, S A, Bedell, M A, Swenberg, J A

“…Chronic alcohol ingestion has been associated with human cancer of the larynx, esophagus, and liver, however the mechanism(s) of ethanol's interaction in…”
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Correlation of O4-ethyldeoxythymidine accumulation, hepatic initiation and hepatocellular carcinoma induction in rats continuously administered diethylnitrosamine by Dyroff, M C, Richardson, F C, Popp, J A, Bedell, M A, Swenberg, J A

“…Recent experiments have demonstrated that O6-ethyldeoxyguanosine (O6-EtdG) is efficiently repaired while O4-ethyldeoxythymidine (O4-EtdT) accumulates in…”
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DNA rearrangements located over 100 kb 5' of the Steel (Sl)-coding region in Steel-panda and Steel-contrasted mice deregulate Sl expression and cause female sterility by disrupting ovarian follicle development by Bedell, M A, Brannan, C I, Evans, E P, Copeland, N G, Jenkins, N A, Donovan, P J

“…The Steel (Sl) locus is essential for the development of germ cells, hematopoietic cells, and melanocytes and encodes a growth factor (Mgf) that is the ligand…”
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Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18 by HUDSON, J. B, BEDELL, M. A, MCCANCE, D. J, LAIMINS, L. A

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Steel-Dickie Mutation Encodes a c-Kit Ligand Lacking Transmembrane and Cytoplasmic Domains by Brannan, Camilynn I., Lyman, Stewart D., Williams, Douglas E., Eisenman, June, Anderson, Dirk M., Cosman, David, Bedell, Mary A., Jenkins, Nancy A., Copeland, Neal G.

“…Mice homozygous for the viable Sl allele steel-Dickie (Sld) are sterile, severely anemic, and black-eyed white. The nature of the Sldmutation was investigated…”
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Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation by BEDELL, M. A, HUDSON, J. B, GOLUB, T. R, TURYK, M. E, HOSKEN, M, WILBANKS, G. D, LAIMINS, L. A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effects of spontaneous KitlSteel mutations on survival and red blood cells of mice by Rajaraman, Sripriya, Wood, Lawrence K, Willhite, Dorian K, Russell, Liane B, Bedell, Mary A

“…Kit ligand (Kitl), which is a member of the helical cytokine superfamily, is encoded by the Steel (Sl) locus of mice and is essential for the development of…”
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