Search Results - "Beckmann, R."

CHEK again: Revisiting the development of CHK1 inhibitors for cancer therapy by McNEELY, S, BECKMANN, R, BENCE LIN, A. K

“…CHEK1 encodes the serine/threonine kinase CHK1, a central component of the DNA damage response. CHK1 regulates cell cycle checkpoints following genotoxic…”
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The impact of baryons on the matter power spectrum from the Horizon-AGN cosmological hydrodynamical simulation by Chisari, N E, Richardson, M L A, Devriendt, J, Dubois, Y, Schneider, A, Le Brun, A M C, Beckmann, R S, Peirani, S, Slyz, A, Pichon, C

“…Accurate cosmology from upcoming weak lensing surveys relies on knowledge of the total matter power spectrum at per cent level at scales k < 10 h Mpc^−1, for…”
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Cosmic evolution of stellar quenching by AGN feedback: clues from the Horizon-AGN simulation by Beckmann, R. S., Devriendt, J., Slyz, A., Peirani, S., Richardson, M. L. A., Dubois, Y., Pichon, C., Chisari, N. E., Kaviraj, S., Laigle, C., Volonteri, M.

“…Abstract The observed massive end of the galaxy stellar mass function is steeper than its predicted dark matter halo counterpart in the standard Λ cold dark…”
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Zooming in on supermassive black holes: how resolving their gas cloud host renders their accretion episodic by Beckmann, R S, Devriendt, J, Slyz, A

“…Born in rapidly evolving mini-haloes during the first billion years of the Universe, supermassive black holes (SMBHs) feed from gas flows spanning many orders…”
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The origin of low-surface-brightness galaxies in the dwarf regime by Jackson, R A, Martin, G, Kaviraj, S, Ramsøy, M, Devriendt, J E G, Sedgwick, T, Laigle, C, Choi, H, Beckmann, R S, Volonteri, M, Dubois, Y, Pichon, C, Yi, S K, Slyz, A, Kraljic, K, Kimm, T, Peirani, S, Baldry, I

“…ABSTRACT Low-surface-brightness galaxies (LSBGs) – defined as systems that are fainter than the surface-brightness limits of past wide-area surveys – form the…”
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Bondi or not Bondi: the impact of resolution on accretion and drag force modelling for supermassive black holes by Beckmann, R S, Slyz, A, Devriendt, J

“…Whilst in galaxy-size simulations, supermassive black holes (SMBHs) are entirely handled by sub-grid algorithms, computational power now allows the accretion…”
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Galaxy–halo alignments in the Horizon-AGN cosmological hydrodynamical simulation by Chisari, N. E., Koukoufilippas, N., Jindal, A., Peirani, S., Beckmann, R. S., Codis, S., Devriendt, J., Miller, L., Dubois, Y., Laigle, C., Slyz, A., Pichon, C.

“…Abstract Intrinsic alignments of galaxies are a significant astrophysical systematic affecting cosmological constraints from weak gravitational lensing…”
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Population statistics of intermediate-mass black holes in dwarf galaxies using the newhorizon simulation by Beckmann, R S, Dubois, Y, Volonteri, M, Dong-Páez, C A, Trebitsch, M, Devriendt, J, Kaviraj, S, Kimm, T, Peirani, S

“…ABSTRACT While it is well established that supermassive black holes (SMBHs) coevolve with their host galaxy, it is currently less clear how lower-mass black…”
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Supermassive black holes in merger-free galaxies have higher spins which are preferentially aligned with their host galaxy by Beckmann, R S, Smethurst, R J, Simmons, B D, Coil, A, Dubois, Y, Garland, I L, Lintott, C J, Martin, G, Peirani, S, Pichon, C

“…ABSTRACT Here, we use the Horizon–active galactic nucleus (AGN) simulation to test whether the spins of supermassive black hole (SMBH) in merger-free galaxies…”
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RAF inhibitor LY3009120 sensitizes RAS or BRAF mutant cancer to CDK4/6 inhibition by abemaciclib via superior inhibition of phospho-RB and suppression of cyclin D1 by Chen, S-H, Gong, X, Zhang, Y, Van Horn, R D, Yin, T, Huber, L, Burke, T F, Manro, J, Iversen, P W, Wu, W, Bhagwat, S V, Beckmann, R P, Tiu, R V, Buchanan, S G, Peng, S-B

“…KRAS , NRAS and BRAF mutations are among the most important oncogenic drivers in many major cancer types, such as melanoma, lung, colorectal and pancreatic…”
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Evidence for non-merger co-evolution of galaxies and their supermassive black holes by Smethurst, R J, Beckmann, R S, Simmons, B D, Coil, A, Devriendt, J, Dubois, Y, Garland, I L, Lintott, C J, Martin, G, Peirani, S

“…ABSTRACT Recent observational and theoretical studies have suggested that supermassive black holes (SMBHs) grow mostly through non-merger (‘secular’)…”
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Mesh and timestep sensitivity of fracture from thermal strains using peridynamics implemented in Abaqus by Beckmann, R., Mella, R., Wenman, M.R.

“…•We modelled fracture using peridynamics in the finite element program Abaqus standard.•At every implicit timestep a uniform temperature increase was applied…”
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Sociodemographic disparities in survival from colorectal cancer in South Australia: a population-wide data linkage study by Beckmann, Kerri R, Bennett, Alice, Young, Graeme P, Cole, Stephen R, Joshi, Rohit, Adams, Jacqui, Singhal, Nimit, Karapetis, Christos, Wattchow, David, Roder, David

“…Inequalities in survival from colorectal cancer (CRC) across socioeconomic groups and by area of residence have been described in various health care settings…”
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Discovery of a diffuse optical line emitting halo in the core of the Centaurus cluster of galaxies: line emission outside the protection of the filaments by Hamer, S L, Fabian, A C, Russell, H R, Salomé, P, Combes, F, Olivares, V, Polles, F L, Edge, A C, Beckmann, R S

“…We present the discovery of diffuse optical line emission in the Centaurus cluster seen with the MUSE (Multi Unit Spectroscopic Explorer) integral field unit…”
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Dynamic Behavior of Trigger Factor on the Ribosome by Deeng, J., Chan, K.Y., van der Sluis, E.O., Berninghausen, O., Han, W., Gumbart, J., Schulten, K., Beatrix, B., Beckmann, R.

“…Trigger factor (TF) is the only ribosome-associated chaperone in bacteria. It interacts with hydrophobic segments in nascent chain (NCs) as they emerge from…”
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Clinical outcomes for men with positive surgical margins after radical prostatectomy—results from the South Australian Prostate Cancer Clinical Outcomes Collaborative community-based registry by Kerri R. Beckmann, Michael E. O'Callaghan, Andrew D. Vincent, Kim L. Moretti, Nicholas R. Brook

“…Objective: Positive surgical margins (PSMs) after radical prostatectomy (RP) indicate failure of surgery to completely clear cancer. PSMs confer an increased…”
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Deposition of microcrystalline intrinsic silicon by the Electrical Asymmetry Effect technique by Hrunski, D., Mootz, F., Zeuner, A., Janssen, A., Rost, H., Beckmann, R., Binder, S., Schüngel, E., Mohr, S., Luggenhölscher, D., Czarnetzki, U., Grabosch, G.

“…Depositing microcrystalline intrinsic silicon films is an important step for the production of thin silicon tandem junction solar cells. Due to the high cost…”
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Oncological outcomes in an Australian cohort according to the new prostate cancer grading groupings by Beckmann, K R, Vincent, A D, O'Callaghan, M E, Cohen, P, Chang, S, Borg, M, Evans, S M, Roder, D M, Moretti, K L

“…A new 5-tiered grading grouping system has recently been endorsed for reporting of prostate cancer (PCa) grade to better reflect escalating risk of progression…”
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Efficacy assessment of three inactivated koi herpes virus antigen preparations against experimental challenge virus infection in common carp by Schmid, T, Gaede, L, Böttcher, K, Bräuer, G, Fichtner, D, Beckmann, R, Speck, S, Becker, F, Truyen, U

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198 Antitumor Effect of Chk1 Inhibitor LY2603618 in Combination with Gemcitabine in SW1990 Pancreas Orthotopic Tumor Model by Wu, W, Bi, C, Beckmann, R, Foreman, R, Wang, T, Bence, A

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