Search Results - "Beckmann, Anna Marie"

A phase 1 antigen dose escalation trial to evaluate safety, tolerability and immunogenicity of the leprosy vaccine candidate LepVax (LEP-F1 + GLA–SE) in healthy adults by Duthie, Malcolm S., Frevol, Aude, Day, Tracey, Coler, Rhea N., Vergara, Julie, Rolf, Tom, Sagawa, Zachary K., Marie Beckmann, Anna, Casper, Corey, Reed, Steven G.

“…•First in human evaluaiton of a defined subunit vaccine for leprosy.•LepVax (LEP-F1 + GLA-SE) demonstrated to be safe.•Comprable immune responses induced by 2…”
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Safety and immunogenicity of a thermostable ID93 + GLA-SE tuberculosis vaccine candidate in healthy adults by Sagawa, Zachary K., Goman, Cristina, Frevol, Aude, Blazevic, Azra, Tennant, Janice, Fisher, Bridget, Day, Tracey, Jackson, Stephen, Lemiale, Franck, Toussaint, Leon, Kalisz, Irene, Jiang, Joe, Ondrejcek, Lisa, Mohamath, Raodoh, Vergara, Julie, Lew, Alan, Beckmann, Anna Marie, Casper, Corey, Hoft, Daniel F., Fox, Christopher B.

“…Adjuvant-containing subunit vaccines represent a promising approach for protection against tuberculosis (TB), but current candidates require refrigerated…”
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CD11a and CD49d enhance the detection of antigen-specific T cells following human vaccination by Christiaansen, Allison F., Dixit, Upasna Gaur, Coler, Rhea N., Marie Beckmann, Anna, Reed, Steven G., Winokur, Patricia L., Zimmerman, M. Bridget, Varga, Steven M., Wilson, Mary E.

“…Determining the efficacy of human vaccines that induce antigen-specific protective CD4 T cell responses against pathogens can be particularly challenging to…”
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A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1 + MPL-SE vaccine for use in the prevention of visceral leishmaniasis by Chakravarty, Jaya, Kumar, Subodh, Trivedi, Sonali, Rai, Vijay K, Singh, Anup, Ashman, Jill A, Laughlin, Elsa M, Coler, Rhea N, Kahn, Stuart J, Beckmann, Anna Marie, Cowgill, Karen D, Reed, Steven G, Sundar, Shyam, Piazza, Franco M

“…Abstract Healthy Indian adult volunteers, with or without a history of leishmaniasis, were evaluated for evidence of previous infection with Leishmania…”
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Dose-sparing effect of two adjuvant formulations with a pandemic influenza A/H7N9 vaccine: A randomized, double-blind, placebo-controlled, phase 1 clinical trial by Tazio Vanni, Beatriz C. Thomé, Erin Sparrow, Martin Friede, Christopher B. Fox, Anna Marie Beckmann, Chuong Huynh, Gabriella Mondini, Daniela H. Silveira, Juliana Y. K. Viscondi, Patrícia Emilia Braga, Anderson da Silva, Maria da Graça Salomão, Roberta O. Piorelli, Joane P. Santos, Vera Lúcia Gattás, Maria Beatriz B. Lucchesi, Mayra M. M. de Oliveira, Marcelo E. Koike, Esper G. Kallas, Lucia M. A. Campos, Eduardo B. Coelho, Marilda A. M. Siqueira, Cristiana C. Garcia, Milene Dias Miranda, Terezinha M. Paiva, Maria do Carmo S. T. Timenetsky, Eduardo A. Adami, Milena A. Akamatsu, Paulo Lee Ho, Alexander R. Precioso

“…The emergence of potentially pandemic viruses has resulted in preparedness efforts to develop candidate vaccines and adjuvant formulations. We evaluated the…”
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The TLR-4 agonist adjuvant, GLA-SE, improves magnitude and quality of immune responses elicited by the ID93 tuberculosis vaccine: first-in-human trial by Coler, Rhea N., Day, Tracey A., Ellis, Ruth, Piazza, Franco M., Beckmann, Anna Marie, Vergara, Julie, Rolf, Tom, Lu, Lenette, Alter, Galit, Hokey, David, Jayashankar, Lakshmi, Walker, Robert, Snowden, Margaret Ann, Evans, Tom, Ginsberg, Ann, Reed, Steven G.

“…Tuberculosis (TB) is the leading cause of infectious death worldwide. Development of improved TB vaccines that boost or replace BCG is a major global health…”
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Safety and immunogenicity of the adjunct therapeutic vaccine ID93 + GLA-SE in adults who have completed treatment for tuberculosis: a randomised, double-blind, placebo-controlled, phase 2a trial by Day, Tracey A, Penn-Nicholson, Adam, Luabeya, Angelique Kany Kany, Fiore-Gartland, Andrew, Du Plessis, Nelita, Loxton, Andre G, Vergara, Julie, Rolf, Tom A, Reid, Tim D, Toefy, Asma, Shenje, Justin, Geldenhuys, Hendrik, Tameris, Michele, Mabwe, Simbarashe, Bilek, Nicole, Bekker, Linda-Gail, Diacon, Andreas, Walzl, Gerhard, Ashman, Jill, Frevol, Aude, Sagawa, Zachary K, Lindestam Arlehamn, Cecilia, Sette, Alessandro, Reed, Steven G, Coler, Rhea N, Scriba, Thomas J, Hatherill, Mark, Beckmann, Anna Marie, Hsu, Fan-Chi, Albertson, Sarah, Veldsman, Ashley, Schreuder, Constance, Smit, Erica, Cloete, Yolundi, Ontong, Cynthia, Filander, Elisabeth, Jacobs, Gail, Keyser, Alana, Africa, Hadn, Mulenga, Humphrey, Noble, Julia, Makhethe, Lebohang, Steyn, Marcia, de Kock, Marwou, Quaqua, Nambitha, Lu, Yiwen, Gutschmidt, Andrea, Thienemann, Friedrich, Kahn, Stuart, Mouton, Angelique, Van Rooyen, Elma, Opperman, Fajwa, Swarts, Ann, Van Schalkwyk, Amaryl, Herselman, Yolandi, Hofmeester, Devona, Amsterdam, Julia, Hassanally, Leya, van der Merwe, Linda, Companie, Alessandro, Rossouw, Susan, Jones, Carolyn, Botes, Natasja, van der Riet, Elize, Goliath, Sandra, Kruger, Sandra, Sinandile, Eunice

“…A therapeutic vaccine that prevents recurrent tuberculosis would be a major advance in the development of shorter treatment regimens. We aimed to assess the…”
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Dose-sparing effect of two adjuvant formulations with a pandemic influenza A/H7N9 vaccine: A randomized, double-blind, placebo-controlled, phase 1 clinical trial by Vanni, Tazio, Thomé, Beatriz C, Sparrow, Erin, Friede, Martin, Fox, Christopher B, Beckmann, Anna Marie, Huynh, Chuong, Mondini, Gabriella, Silveira, Daniela H, Viscondi, Juliana Y K, Braga, Patrícia Emilia, Silva, Anderson da, Salomão, Maria da Graça, Piorelli, Roberta O, Santos, Joane P, Gattás, Vera Lúcia, Lucchesi, Maria Beatriz B, Oliveira, Mayra M M de, Koike, Marcelo E, Kallas, Esper G, Campos, Lucia M A, Coelho, Eduardo B, Siqueira, Marilda A M, Garcia, Cristiana C, Miranda, Milene Dias, Paiva, Terezinha M, Timenetsky, Maria do Carmo S T, Adami, Eduardo A, Akamatsu, Milena A, Ho, Paulo Lee, Precioso, Alexander R

“…The emergence of potentially pandemic viruses has resulted in preparedness efforts to develop candidate vaccines and adjuvant formulations. We evaluated the…”
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The adjuvant GLA-AF enhances human intradermal vaccine responses by Carter, Darrick, van Hoeven, Neal, Baldwin, Susan, Levin, Yotam, Kochba, Efrat, Magill, Al, Charland, Nathalie, Landry, Nathalie, Nu, Khin, Frevol, Aude, Ashman, Jill, Sagawa, Zachary K, Beckmann, Anna Marie, Reed, Steven G

“…Adjuvants are key to shaping the immune response to vaccination, but to date, no adjuvant suitable for human use has been developed for intradermal vaccines…”
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A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1 + MPL-SE vaccine when used in combination with meglumine antimoniate for the treatment of cutaneous leishmaniasis by Nascimento, Evaldo, Fernandes, Demetrios F, Vieira, Edva P, Campos-Neto, Antonio, Ashman, Jill A, Alves, Fabiana P, Coler, Rhea N, Bogatzki, Lisa Y, Kahn, Stuart J, Beckmann, Anna Marie, Pine, Samuel O, Cowgill, Karen D, Reed, Steven G, Piazza, Franco M

“…Abstract Forty-four adult patients with cutaneous leishmaniasis (CL) were enrolled in a randomized, double-blind, controlled, dose-escalating clinical trial…”
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A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1 + MPL-SE vaccine when used in combination with sodium stibogluconate for the treatment of mucosal leishmaniasis by Llanos-Cuentas, Alejandro, Calderón, Wessmark, Cruz, María, Ashman, Jill A, Alves, Fabiana P, Coler, Rhea N, Bogatzki, Lisa Y, Bertholet, Sylvie, Laughlin, Elsa M, Kahn, Stuart J, Beckmann, Anna Marie, Cowgill, Karen D, Reed, Steven G, Piazza, Franco M

“…Abstract Adult patients with mucosal leishmaniasis (ML) were enrolled in a randomized, double-blind, placebo-controlled, dose-escalating clinical trial and…”
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Safety and immunogenicity of a defined vaccine for the prevention of cutaneous leishmaniasis by Vélez, Iván D, Gilchrist, Katherine, Martínez, Sofía, Ramírez-Pineda, José R, Ashman, Jill A, Alves, Fabiana P, Coler, Rhea N, Bogatzki, Lisa Y, Kahn, Stuart J, Beckmann, Anna Marie, Cowgill, Karen D, Reed, Steven G, Piazza, Franco M

“…Abstract Healthy Colombian adult volunteers with no history of leishmaniasis were evaluated for evidence of previous subclinical infection with Leishmania…”
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Lyophilization process engineering and thermostability of ID93 + GLA-SE, a single-vial adjuvanted subunit tuberculosis vaccine candidate for use in clinical studies by Dutill, Timothy S., Archer, Michelle C., McCollum, Joseph, Press, Chris, McNeill, Lisa, Hawkins, Linda, Phan, Tony, Laursen, Erik D., Cabullos, Richard, Bouchard, Lisa, Castro, Regie J., Lin, Mong-Wu, Roco, Jeralyn, Blois, Cecile, Adeagbo, Babatunde A., Guderian, Jeffrey A., Gerhardt, Alana, Beckmann, Anna Marie, Trappler, Edward H., Kramer, Ryan M., Fox, Christopher B.

“…Promising clinical efficacy results have generated considerable enthusiasm for the potential impact of adjuvant-containing subunit tuberculosis vaccines. The…”
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Oral Cancer Risk in Relation to Sexual History and Evidence of Human Papillomavirus Infection by Schwartz, Stephen M., Daling, Janet R., Madeleine, Margaret M., Doody, David R., Fitzgibbons, E. Dawn, Wipf, Gregory C., Carter, Joseh J., Mao, Er-Jia, Huang, Shixuan, Beckmann, Anna Marie, McDougall, James K., Galloway, Denise A.

“…Background: Experimental models and analyses of human tumors suggest that oncogenic, sexually transmittable human papillomaviruses (HPVs) are etiologic factors…”
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Human papillomavirus types 52 and 58 are prevalent in cervical cancers from Chinese women by HUANG, S, AFONINA, I, MILLER, B. A, BECKMANN, A. M

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Safety and immunogenicity of a defined vaccine for the prevention of cutaneous leishmaniasis by VELEZ, Iván D, GILCHRIST, Katherine, COWGILL, Karen D, REED, Steven G, PIAZZA, Franco M, MARTINEZ, Sofia, RAMIREZ-PINEDA, José R, ASHMAN, Jill A, ALVES, Fabiana P, COLER, Rhea N, BOGATZKI, Lisa Y, KAHN, Stuart J, BECKMANN, Anna Marie

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Human papilloma viruses andp53 mutations in normal, pre-malignant and malignant oral epithelia by Mao, Er-Jia, Schwartz, Stephen M., Daling, Janet R., Oda, Dolphine, Tickman, Liz, Beckmann, Anna Marie

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A Cohort Study of the Risk of Cervical Intraepithelial Neoplasia Grade 2 or 3 in Relation to Papillomavirus Infection by Koutsky, Laura A, Holmes, King K, Critchlow, Cathy W, Stevens, Claire E, Paavonen, Jorma, Beckmann, Anna Marie, DeRouen, Timothy A, Galloway, Denise A, Vernon, Debra, Kiviat, Nancy B

“…THE dramatic decline in the incidence of cervical cancer in this country over the past 40 years has been attributed largely to the widespread use of cytologic…”
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Human papillomavirus types 52 and 58 are prevalent in cervical cancers from Chinese women by Huang, Shixuan, Afonina, Irina, Miller, Beth A., Beckmann, Anna Marie

“…A substantial body of evidence has confirmed human papillomavirus (HPV) infection as an etiologic agent in human cervical cancer. To evaluate the association…”
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Cofactors With Human Papillomavirus in a Population-Based Study of Vulvar Cancer by Madeleine, Margaret M., Daling, Janet R., Schwartz, Stephen M., Carter, Joseph J., Wipf, Gregory C., Beckmann, Anna Marie, McKnight, Barbara, Kurman, Robert J., Hagensee, Michael E., Galloway, Denise A.

“…Background: Human papillomavirus (HPV) has been previously associated with vulvar cancer. In a population-based study, we examined whether exposure to HPV,…”
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