Search Results - "Beckman, Matthew J."

Multipotent adipose stromal cells and breast cancer development: Think globally, act locally by Zhao, Min, Dumur, Cathy I., Holt, Shawn E., Beckman, Matthew J., Elmore, Lynne W.

“…It has long been appreciated that stromal cells within the breast tumor microenvironment contribute to mammary carcinogenesis. However, to date, very little is…”
Get full text

Dual functions of autophagy in the response of breast tumor cells to radiation: cytoprotective autophagy with radiation alone and cytotoxic autophagy in radiosensitization by vitamin D 3 by Bristol, Molly L, Di, Xu, Beckman, Matthew J, Wilson, Eden N, Henderson, Scott C, Maiti, Aparna, Fan, Zhen, Gewirtz, David A

“…In MCF-7 breast tumor cells, ionizing radiation promoted autophagy that was cytoprotective; pharmacological or genetic interference with autophagy induced by…”
Get full text

Dual functions of autophagy in the response of breast tumor cells to radiation: Cytoprotective autophagy with radiation alone and cytotoxic autophagy in radiosensitization by vitamin D3 by Bristol, Molly L., Di, Xu, Beckman, Matthew J., Wilson, Eden N., Henderson, Scott C., Maiti, Aparna, Fan, Zhen, Gewirtz, David A

“…In MCF-7 breast tumor cells, ionizing radiation promoted autophagy that was cytoprotective; pharmacological or genetic interference with autophagy induced by…”
Get full text

QW-1624F2-2, a synthetic analogue of 1,25-dihydroxyvitamin D3, enhances the response to other deltanoids and suppresses the invasiveness of human metastatic breast tumor cells by Sundaram, Sujatha, Beckman, Matthew J, Bajwa, Amandeep, Wei, Jeffrey, Smith, Kathleen M, Posner, Gary H, Gewirtz, David A

“…The enzyme 24-hydroxylase, also known as CYP24, metabolizes 1,25-dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] and is an established marker of vitamin D activity. Our…”
Get full text

Extracellular Calcium-sensing Receptor Activation Induces Vitamin D Receptor Levels in Proximal Kidney HK-2G Cells by a Mechanism That Requires Phosphorylation of p38α MAPK by Maiti, Aparna, Hait, Nitai C., Beckman, Matthew J.

“…In hypocalcaemia, elevated parathyroid hormone transitorily down-regulates the kidney vitamin D receptor, which returns to normal levels with the rise in serum…”
Get full text

Extracellular calcium is a direct effecter of VDR levels in proximal tubule epithelial cells that counter-balances effects of PTH on renal Vitamin D metabolism by Maiti, Aparna, Beckman, Matthew J.

“…In renal proximal tubules, VDR is transiently decreased by parathyroid hormone (PTH) during times of hypocalcemia and returns to normal levels with the rise in…”
Get full text

Multiple factor interactions in biomimetic mineralization of electrospun scaffolds by Madurantakam, Parthasarathy A, Rodriguez, Isaac A, Cost, Christopher P, Viswanathan, Ramakrishnan, Simpson, David G, Beckman, Matthew J, Moon, Peter C, Bowlin, Gary L

“…Abstract One of the major limitations in scaffold-based bone tissue engineering has been the inability to increase the loading of biologically active inorganic…”
Get full text

Specific regulation of CYP27B1 and VDR in proximal versus distal renal cells by Bajwa, Amandeep, Forster, Megan N., Maiti, Aparna, Woolbright, Benjamin L., Beckman, Matthew J.

“…In this study, we utilized murine renal proximal (MPCT-G) and distal (DKC-8) tubular epithelial cell lines to compare the gene expressions and promoter…”
Get full text

Evaluation of thrombogenic potential of electrospun bioresorbable vascular graft materials: Acute monocyte tissue factor expression by Wolfe, Patricia S., Madurantakam, Parthasarathy, Garg, Koyal, Sell, Scott A., Beckman, Matthew J., Bowlin, Gary L.

“…The purpose of this study was to quantify the acute expression of tissue factor (TF) by monocytes on interaction with electrospun bioresorbable constructs. A…”
Get full text

Expression of RANKL in Osteolytic Membranes: Association with Fibroblastic Cell Markers by Ramage, Samuel C, Urban, Nicole H, Jiranek, William A, Maiti, Aparna, Beckman, Matthew J

“…BackgroundAseptic loosening is often mentioned as the primary reason for costly revision of total joint arthroplasties. Receptor activator of nuclear factor-κB…”
Get full text

High prevalence of vitamin D deficiency in African American kidney transplant recipients by Tripathi, Shreyank S, Gibney, Eric M, Gehr, Todd W B, King, Anne L, Beckman, Matthew J

“…Kidney transplant patients are at high risk for developing Vitamin D(3) deficiency. The prevalence rates of 25(OH) Vitamin D(3) deficiency and its association…”
Get full text

Evaluation of biological activity of bone morphogenetic proteins on exposure to commonly used electrospinning solvents by Madurantakam, Parthasarathy A, Rodriguez, Isaac A, Beckman, Matthew J, Simpson, David G, Bowlin, Gary L

“…Bone tissue engineering is one of the emerging strategies for developing functionally viable bone substitutes. The recent trend in bone tissue engineering is…”
Get full text

Effects of α/β-androstenediol immune regulating hormones on bone remodeling and apoptosis in osteoblasts by Urban, Nicole H., Chamberlin, Brett, Ramage, Samuel, Roberts, Zachary, Loria, Roger M., Beckman, Matthew J.

“…A large body of evidence suggests that the immune system directly impacts bone physiology. We tested whether immune regulating hormones (IRH),…”
Get full text

Expression of RANKL in osteolytic membranes : Association with fibroblastic cell markers by RAMAGE, Samuel C, URBAN, Nicole H, JIRANEK, William A, MAITI, Aparna, BECKMAN, Matthew J

“…Aseptic loosening is often mentioned as the primary reason for costly revision of total joint arthroplasties. Receptor activator of nuclear factor-kappaB…”
Get full text

A Switch Between Cytoprotective and Cytotoxic Autophagy in the Radiosensitization of Breast Tumor Cells by Chloroquine and Vitamin D by Wilson, Eden N., Bristol, Molly L., Di, Xu, Maltese, William A., Koterba, Kristen, Beckman, Matthew J., Gewirtz, David A.

“…Calcitriol or 1,25-dihydroxyvitamin D3, the hormonally active form of vitamin D, as well as vitamin D analogs, has been shown to increase sensitivity to…”
Get full text

Human 25-Hydroxyvitamin D3-24-Hydroxylase, a Multicatalytic Enzyme by Beckman, Matthew J, Tadikonda, Praveen, Werner, Elizabeth, Prahl, Jean, Yamada, Sachiko, DeLuca, Hector F

“…Human 25-hydroxyvitamin D-24-hydroxylase has been expressed in Spodoptera frugiperda (Sf21) insect cells using the previously cloned cDNA in baculovirus…”
Get full text

5-HT 5a receptors in the carotid body chemoreception pathway of rat by Wang, Zun-Yi, Keith, Ingegerd M., Beckman, Matthew J., Brownfield, Mark S., Vidruk, Edward H., Bisgard, Gerald E.

Get full text

Abstract 3957: Cell death and growth arrest pathways mediating the actions of stilbene 5C in HCT-116 colon cancer cells by Alotaibi, Moureq R., Beckman, Matthew J., Di, Xu, Lee, Ray, Gewirtz, David A.

“…Abstract The stilbene derivative, cis-3, 4′, 5-trimethoxy-3′-aminostilbene (stilbene 5c), is a potentially potent antitumor agent that acts via binding to the…”
Get full text

Abstract 2675: Radiosensitization of breast cancer cells by Vitamin D or chloroquine through modulation of the dual cytoprotective and cytotoxic functions of autophagy by Wilson, Eden N., Bristol, Molly L., Di, Xu, Beckman, Matthew J., Koterba, Kristen, Gewirtz, David A.

“…Abstract Introduction: Previous studies in our laboratory have demonstrated that the active form of vitamin D, 1,25-di hydroxy vitamin D3 (1,25-D3), or its…”
Get full text

Extracellular Calcium-sensing Receptor Activation Induces Vitamin D Receptor Levels in Proximal Kidney HK-2G Cells by a Mechanism That Requires Phosphorylation of p38α MAPK by Aparna Maiti, Nitai C. Hait, Matthew J. Beckman

“…In hypocalcaemia, elevated parathyroid hormone transitorily down-regulates the kidney vitamin D receptor, which returns to normal levels with the rise in serum…”
Get full text