Search Results - "Beckham, Suzanne"
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Identification of the RT–RH/IN cleavage site of HTLV-I
Published in Biochemical and biophysical research communications (10-01-2003)“…Human T-cell leukemia virus type 1 (HTLV-1) is a type C human retrovirus and is the causative agent of adult T-cell leukemia and other diseases. The enzymatic…”
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Molecular Recognition in Methanol: The First Example of Hydrogen-Bond-Mediated Self-Association of a Calix[4]arene in Polar, Protic Solvent
Published in Journal of the American Chemical Society (10-07-2002)“…Tetraalaninecalixarene was prepared by coupling of tetraaminocalix[4]arene with alanine. It dimerizes in methanol, providing the first example of a substituted…”
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Failed attempt to observe phosphorescent excimers of 1-bromonaphthalene
Published in Journal of physical chemistry (1952) (01-12-1988)Get full text
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Synthesis of a peptidocalix[4]arene library and identification of compounds with hydrolytic activity
Published in Bioorganic chemistry (01-02-2005)“…A 120 member library of peptidocalix[4]arenes was synthesized and screened for catalysis of the hydrolysis of p-nitrophenyl acetate. His-Ser-His-calix[4]arene…”
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The intramolecular addition of silylated alkynes to aldehydes: Methodology for the construction of cyclic enediynes and its application to dynemicin analogs
Published in Tetrahedron letters (09-01-1995)“…Upon treatment with CsF, silylated alkynes react intramolecularly with aldehydes or iminium ions to form in one step in the presence of electrophilic trapping…”
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Dynemicin A and photochemically activated analogs: Computer modeling, synthetic, and DNA cleavage studies
Published 01-01-1995“…During the past ten years, the enediyne anti-tumor antibiotics have emerged as a promising class of chemotherapeutic agents and medicinal leads. In addition,…”
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Dissertation -
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HTLV-I Protease Cleavage of P19/24 Substrates Is Not Dependent on NaCl Concentration
Published in Bioorganic chemistry (01-04-2002)“…Understanding the factors that affect the activity of Human T-cell Leukemia Virus type I (HTLV-I) protease is essential for the discovery of inhibitors to be…”
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Journal Article -
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Studies on DNA-Cleaving Agents: Computer Modeling Analysis of the Mechanism of Activation and Cleavage of Dynemicin-Oligonucleotide Complexes
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1991)“…Dynemicin A is a recently identified antitumor antibiotic. Upon activation, dynemicin is reported to cause double-stranded cleavage of DNA, putatively through…”
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Understanding HTLV-I Protease
Published in Chemistry & Biology (01-05-2003)“…Human T cell leukemia virus type I (HTLV-I) is a human retrovirus that has been clinically associated with adult T cell leukemia/lymphoma, and it has been…”
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