Search Results - "Becker‐Baldus, Johanna"

The Desensitized Channelrhodopsin‐2 Photointermediate Contains 13 ‐cis, 15 ‐syn Retinal Schiff Base by Becker‐Baldus, Johanna, Leeder, Alexander, Brown, Lynda J., Brown, Richard C. D., Bamann, Christian, Glaubitz, Clemens

“…Channelrhodopsin‐2 (ChR2) is a light‐gated cation channel and was used to lay the foundations of optogenetics. Its dark state X‐ray structure has been…”
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The Conformational Equilibrium of the Neuropeptide Y2 Receptor in Bilayer Membranes by Krug, Ulrike, Gloge, Anika, Schmidt, Peter, Becker‐Baldus, Johanna, Bernhard, Frank, Kaiser, Anette, Montag, Cindy, Gauglitz, Marcel, Vishnivetskiy, Sergey A., Gurevich, Vsevolod V., Beck‐Sickinger, Annette G., Glaubitz, Clemens, Huster, Daniel

“…Dynamic structural transitions within the seven‐transmembrane bundle represent the mechanism by which G‐protein‐coupled receptors convert an extracellular…”
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Overcoming Volume Selectivity of Dipolar Recoupling in Biological Solid‐State NMR Spectroscopy by Tošner, Zdeněk, Sarkar, Riddhiman, Becker‐Baldus, Johanna, Glaubitz, Clemens, Wegner, Sebastian, Engelke, Frank, Glaser, Steffen J., Reif, Bernd

“…Dipolar recoupling in solid‐state NMR is an essential method for establishing correlations between nuclei that are close in space. In applications on protein…”
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Light‐Induced Uncaging for Time‐Resolved Observations of Biochemical Reactions by MAS NMR Spectroscopy by Mos, Julian, Jakob, Andreas, Becker‐Baldus, Johanna, Heckel, Alexander, Glaubitz, Clemens

“…Light‐induced activation of biomolecules by uncaging of photolabile protection groups has found many applications for triggering biochemical reactions with…”
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Synthesis of isotopically labeled all‐trans retinals for DNP‐enhanced solid‐state NMR studies of retinylidene proteins by Leeder, Alexander J., Brown, Lynda J., Becker‐Baldus, Johanna, Mehler, Michaela, Glaubitz, Clemens, Brown, Richard C.D.

“…Three all‐trans retinals containing multiple 13C labels have been synthesized to enable dynamic nuclear polarization enhanced solid‐state magic angle spinning…”
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Photocycle-dependent conformational changes in the proteorhodopsin cross-protomer Asp–His–Trp triad revealed by DNP-enhanced MAS-NMR by Maciejko, Jakob, Kaur, Jagdeep, Becker-Baldus, Johanna, Glaubitz, Clemens

“…Proteorhodopsin (PR) is a highly abundant, pentameric, light-driven proton pump. Proton transfer is linked to a canonical photocycle typical for microbial ion…”
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Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy by Becker-Baldus, Johanna, Bamann, Christian, Saxena, Krishna, Gustmann, Henrik, Brown, Lynda J., Brown, Richard C. D., Reiter, Christian, Bamberg, Ernst, Wachtveitl, Josef, Schwalbe, Harald, Glaubitz, Clemens

“…Channelrhodopsin-2 fromChlamydomonas reinhardtiiis a light-gated ion channel. Over recent years, this ion channel has attracted considerable interest because…”
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Visualizing Specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by Dynamic-Nuclear-Polarization-Enhanced Solid-State NMR by Maciejko, Jakob, Mehler, Michaela, Kaur, Jagdeep, Lieblein, Tobias, Morgner, Nina, Ouari, Olivier, Tordo, Paul, Becker-Baldus, Johanna, Glaubitz, Clemens

“…Membrane proteins often form oligomeric complexes within the lipid bilayer, but factors controlling their assembly are hard to predict and experimentally…”
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Solid-state NMR analysis of the sodium pump Krokinobacter rhodopsin 2 and its H30A mutant by Kaur, Jagdeep, Kriebel, Clara Nassrin, Eberhardt, Peter, Jakdetchai, Orawan, Leeder, Alexander J., Weber, Ingrid, Brown, Lynda J., Brown, Richard C.D., Becker-Baldus, Johanna, Bamann, Christian, Wachtveitl, Josef, Glaubitz, Clemens

“…Krokinobacter eikastus rhodopsin 2 (KR2) is a pentameric, light-driven ion pump, which selectively transports sodium or protons. The mechanism of ion…”
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Global response of diacylglycerol kinase towards substrate binding observed by 2D and 3D MAS NMR by Möbius, Kristin, Kazemi, Sina, Güntert, Peter, Jakob, Andreas, Heckel, Alexander, Becker-Baldus, Johanna, Glaubitz, Clemens

“…Escherichia coli diacylglycerol kinase (DGK) is an integral membrane protein, which catalyses the ATP-dependent phosphorylation of diacylglycerol (DAG) to…”
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Chromophore Distortions in Photointermediates of Proteorhodopsin Visualized by Dynamic Nuclear Polarization-Enhanced Solid-State NMR by Mehler, Michaela, Eckert, Carl Elias, Leeder, Alexander J, Kaur, Jagdeep, Fischer, Tobias, Kubatova, Nina, Brown, Lynda J, Brown, Richard C. D, Becker-Baldus, Johanna, Wachtveitl, Josef, Glaubitz, Clemens

“…Proteorhodopsin (PR) is the most abundant retinal protein on earth and functions as a light-driven proton pump. Despite extensive efforts, structural data for…”
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Structural Basis of the Green–Blue Color Switching in Proteorhodopsin as Determined by NMR Spectroscopy by Mao, Jiafei, Do, Nhu-Nguyen, Scholz, Frank, Reggie, Lenica, Mehler, Michaela, Lakatos, Andrea, Ong, Yean-Sin, Ullrich, Sandra J, Brown, Lynda J, Brown, Richard C. D, Becker-Baldus, Johanna, Wachtveitl, Josef, Glaubitz, Clemens

“…Proteorhodopsins (PRs) found in marine microbes are the most abundant retinal-based photoreceptors on this planet. PR variants show high levels of…”
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Probing the allosteric NBD-TMD crosstalk in the ABC transporter MsbA by solid-state NMR by Novischi, S. Y. Phoebe, Karoly-Lakatos, Andrea, Chok, Kerby, Bonifer, Christian, Becker-Baldus, Johanna, Glaubitz, Clemens

“…The ABC transporter MsbA plays a critical role in Gram-negative bacteria in the regulation of the outer membrane by translocating core-LPS across the inner…”
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Ceramide–lipid interactions studied by MD simulations and solid-state NMR by Dutagaci, Bercem, Becker-Baldus, Johanna, Faraldo-Gómez, José D., Glaubitz, Clemens

“…Ceramides play a key modulatory role in many cellular processes, which results from their effect on the structure and dynamics of biological membranes. In this…”
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Probing the Conformational Space of the Cannabinoid Receptor 2 and a Systematic Investigation of DNP-Enhanced MAS NMR Spectroscopy of Proteins in Detergent Micelles by Becker-Baldus, Johanna, Yeliseev, Alexei, Joseph, Thomas T., Sigurdsson, Snorri Th, Zoubak, Lioudmila, Hines, Kirk, Iyer, Malliga R., van den Berg, Arjen, Stepnowski, Sam, Zmuda, Jon, Gawrisch, Klaus, Glaubitz, Clemens

“…Tremendous progress has been made in determining the structures of G-protein coupled receptors (GPCR) and their complexes in recent years. However,…”
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The Desensitized Channelrhodopsin‐2 Photointermediate Contains 13 ‐cis, 15 ‐syn Retinal Schiff Base by Becker‐Baldus, Johanna, Leeder, Alexander, Brown, Lynda J., Brown, Richard C. D., Bamann, Christian, Glaubitz, Clemens

“…Channelrhodopsin‐2 (ChR2) is a light‐gated cation channel and was used to lay the foundations of optogenetics. Its dark state X‐ray structure has been…”
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Photocycle and Vectorial Proton Transfer in a Rhodopsin from the Eukaryote Oxyrrhis marina by Janke, Christian, Scholz, Frank, Becker-Baldus, Johanna, Glaubitz, Clemens, Wood, Phillip G, Bamberg, Ernst, Wachtveitl, Josef, Bamann, Christian

“…Retinylidene photoreceptors are ubiquitously present in marine protists as first documented by the identification of green proteorhodopsin (GPR). We present a…”
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Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies by Ditzinger, Felix, Price, Daniel J, Nair, Anita, Becker-Baldus, Johanna, Glaubitz, Clemens, Dressman, Jennifer B, Saal, Christoph, Kuentz, Martin

“…Amorphous formulation technologies to improve oral absorption of poorly soluble active pharmaceutical ingredients (APIs) have become increasingly prevalent…”
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Probing the photointermediates of light-driven sodium ion pump KR2 by DNP-enhanced solid-state NMR by Jakdetchai, Orawan, Eberhardt, Peter, Asido, Marvin, Kaur, Jagdeep, Kriebel, Clara Nassrin, Mao, Jiafei, Leeder, Alexander J, Brown, Lynda J, Brown, Richard C D, Becker-Baldus, Johanna, Bamann, Christian, Wachtveitl, Josef, Glaubitz, Clemens

“…The functional mechanism of the light-driven sodium pump rhodopsin 2 (KR2) raises fundamental questions since the transfer of cations must differ from the…”
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MAS NMR Study of the Bacterial ABC Transporter ArtMP by Lange, Vivien, Becker-Baldus, Johanna, Kunert, Britta, van Rossum, Barth-Jan, Casagrande, Fabio, Engel, Andreas, Roske, Yvette, Scheffel, Frank M, Schneider, Erwin, Oschkinat, Hartmut

“…ATP-binding cassette (ABC) transport systems facilitate the translocation of substances, like amino acids, across cell membranes energised by ATP hydrolysis…”
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