Search Results - "Becker, Rüdiger"

Connexin 43 gene therapy prevents persistent atrial fibrillation in a porcine model by BIKOU, Olympia, THOMAS, Dierk, BAUER, Alexander, TRAPPE, Kerstin, LUGENBIEL, Patrick, KELEMEN, Kamilla, KOCH, Martin, SOUCEK, Radim, VOSS, Frederik, BECKER, Rudiger, KATUS, Hugo A

“…Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and effective treatment of AF still remains an unmet medical need. AF is associated…”
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Continuous Stroke Unit Electrocardiographic Monitoring Versus 24-Hour Holter Electrocardiography for Detection of Paroxysmal Atrial Fibrillation After Stroke by Rizos, Timolaos, Güntner, Janina, Jenetzky, Ekkehart, Marquardt, Lars, Reichardt, Christine, Becker, Rüdiger, Reinhardt, Roland, Hepp, Thomas, Kirchhof, Paulus, Aleynichenko, Elena, Ringleb, Peter, Hacke, Werner, Veltkamp, Roland

“…Cardioembolism in paroxysmal atrial fibrillation (pxAF) is a frequent cause of ischemic stroke. Sensitive detection of pxAF after stroke is crucial for…”
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Prophylactic implantation of cardioverter-defibrillator in patients with severe cardiac amyloidosis and high risk for sudden cardiac death by Kristen, Arnt V., MD, Dengler, Thomas J., MD, Hegenbart, Ute, MD, Schonland, Stefan O., MD, Goldschmidt, Hartmut, MD, Sack, Falk-Udo, MD, Voss, Frederik, MD, Becker, Rüdiger, MD, Katus, Hugo A., MD, Bauer, Alexander, MD

“…Background Cardiac light-chain amyloidosis carries a high risk for death predominantly from progressive cardiomyopathy or sudden death (SCD). Independent risk…”
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HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells by Staudacher, Ingo, Jehle, Julian, Staudacher, Kathrin, Pledl, Hans-Werner, Lemke, Dieter, Schweizer, Patrick A, Becker, Rüdiger, Katus, Hugo A, Thomas, Dierk

“…Glioblastoma (GB) is associated with poor patient survival owing to uncontrolled tumor proliferation and resistance to apoptosis. Human ether-a-go-go-related…”
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Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels by Schmidt, Constanze, Wiedmann, Felix, Schweizer, Patrick A., Becker, Rüdiger, Katus, Hugo A., Thomas, Dierk

“…Dronedarone is currently used for the treatment of paroxysmal and persistent atrial fibrillation (AF). Pharmacological inhibition of cardiac two-pore-domain…”
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Identification and functional characterization of zebrafish K(2P)10.1 (TREK2) two-pore-domain K(+) channels by Gierten, Jakob, Hassel, David, Schweizer, Patrick A, Becker, Rüdiger, Katus, Hugo A, Thomas, Dierk

“…Two-pore-domain potassium (K(2P)) channels mediate K(+) background currents that stabilize the resting membrane potential and contribute to repolarization of…”
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Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go–related gene mutant by Soucek, Radim, MD, Thomas, Dierk, MD, Kelemen, Kamilla, MD, Bikou, Olympia, MD, Seyler, Claudia, PhD, Voss, Frederik, MD, Becker, Rüdiger, MD, Koenen, Michael, PhD, Katus, Hugo A., MD, Bauer, Alexander, MD

“…Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Gene therapy–dependent modulation of atrial electrophysiology may provide…”
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Suppression of persistent atrial fibrillation by genetic knockdown of caspase 3: a pre-clinical pilot study by Trappe, Kerstin, Thomas, Dierk, Bikou, Olympia, Kelemen, Kamilla, Lugenbiel, Patrick, Voss, Frederik, Becker, Rüdiger, Katus, Hugo A., Bauer, Alexander

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Initial experience with robotic navigation for catheter ablation of paroxysmal and persistent atrial fibrillation by Thomas, Dierk, MD, Scholz, Eberhard P., MD, Schweizer, Patrick A., MD, Katus, Hugo A., MD, Becker, Rüdiger, MD

“…Abstract Background and Purpose Remote robotic navigation (RRN) technology has been developed to facilitate catheter ablation of symptomatic atrial…”
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Dronedarone: current evidence for its safety and efficacy in the management of atrial fibrillation by Schweizer, Patrick A, Becker, Rüdiger, Katus, Hugo A, Thomas, Dierk

“…Atrial fibrillation (AF) is the most common sustained arrhythmia. Management of AF includes rate control, rhythm control if necessary, prevention of…”
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Comparison of myocardial infarct size measurements between noncontact mapping and cardiac contrast enhanced MRI by Steen, Henning, Voss, Frederik, Becker, Rüdiger, Katus, Hugo A, Giannitsis, Evangelos

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Alternative splicing determines mRNA translation initiation and function of human K2P10.1 K+ channels by Staudacher, Kathrin, Baldea, Ioana, Kisselbach, Jana, Staudacher, Ingo, Rahm, Ann‐Kathrin, Schweizer, Patrick A., Becker, Rüdiger, Katus, Hugo A., Thomas, Dierk

“…Non‐technical summary The resting membrane potential of excitable cells such as neurones and cardiac myocytes depends on the distribution of potassium ions…”
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PKC‐dependent activation of human K2P18.1 K+ channels by Rahm, Ann‐Kathrin, Gierten, Jakob, Kisselbach, Jana, Staudacher, Ingo, Staudacher, Kathrin, Schweizer, Patrick A, Becker, Rüdiger, Katus, Hugo A, Thomas, Dierk

“…BACKGROUND AND PURPOSE Two‐pore‐domain K+ channels (K2P) mediate K+ background currents that modulate the membrane potential of excitable cells. K2P18.1…”
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Suppression of persistent atrial fibrillation by genetic knockdown of caspase 3: a pre-clinical pilot study by Trappe, Kerstin, Thomas, Dierk, Bikou, Olympia, Kelemen, Kamilla, Lugenbiel, Patrick, Voss, Frederik, Becker, Rüdiger, Katus, Hugo A, Bauer, Alexander

“…Atrial fibrillation (AF) is linked to cardiomyocyte apoptosis, leading to atrial remodelling and reduction in electrical conduction velocity. We hypothesized…”
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Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation by Duhme, Nana, Schweizer, Patrick A, Thomas, Dierk, Becker, Rüdiger, Schröter, Julian, Barends, Thomas R M, Schlichting, Ilme, Draguhn, Andreas, Bruehl, Claus, Katus, Hugo A, Koenen, Michael

“…HCN4 channels are involved in generation, regulation, and stabilization of heart rhythm and channel dysfunction is associated with inherited sinus bradycardia…”
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Anxiety Disorders in Patients with Implantable Cardioverter Defibrillators: Frequency, Course, Predictors, and Patients' Requests for Treatment by LANG, SASKIA, BECKER, RÜDIGER, WILKE, STEFANIE, HARTMANN, MECHTHILD, HERZOG, WOLFGANG, LÖWE, BERND

“…Objectives To determine (1) the frequency and course of anxiety disorders in patients with implantable cardioverter defibrillators (ICDs), (2) the predictors…”
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Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K+ (K2P) channels by Schmidt, Constanze, Wiedmann, Felix, Schweizer, Patrick A., Becker, Rüdiger, Katus, Hugo A., Thomas, Dierk

“…Class IC antiarrhythmic drugs are commonly used for rhythm control in atrial fibrillation. In addition, class I drugs are administered to suppress ventricular…”
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EHRA Expert Consensus Statement on the management of cardiovascular implantable electronic devices in patients nearing end of life or requesting withdrawal of therapy by Padeletti, Luigi, Arnar, David O, Boncinelli, Lorenzo, Brachman, Johannes, Camm, John A, Daubert, Jean Claude, Hassam, Sarah K, Kassam, Sarah, Deliens, Luc, Glikson, Michael, Hayes, David, Israel, Carsten, Lampert, Rachel, Lobban, Trudie, Raatikainen, Pekka, Siegal, Gil, Vardas, Panos, Kirchhof, Paulus, Becker, Rüdiger, Cosio, Francisco, Loh, Peter, Cobbe, Stuart, Grace, Andrew, Morgan, John

“…The purpose of this Consensus Statement is to focus on implantable cardioverter-defibrillator (ICD) deactivation in patients with irreversible or terminal…”
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Anti-KCNQ1 K⁺ channel autoantibodies increase IKs current and are associated with QT interval shortening in dilated cardiomyopathy by Li, Jin, Seyler, Claudia, Wiedmann, Felix, Schmidt, Constanze, Schweizer, Patrick A, Becker, Rüdiger, Katus, Hugo A, Thomas, Dierk

“…Autoimmune-associated proarrhythmia in dilated cardiomyopathy (DCM) is poorly understood. Given the significance of KCNQ1 potassium channels in heart rhythm…”
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Implantable Defibrillators With Enhanced Detection Algorithms: Detection Performance and Safety Results from the PainFree SST Study by WOLLMANN, CHRISTIAN G., LAWO, THOMAS, KÜHLKAMP, VOLKER, BECKER, RÜDIGER, GARUTTI, CLAUDIO, JACKSON, TROY, BROWN, MARK L., MAYR, HARALD

“…Background Implantable defibrillators (ICD) are highly effective in reducing arrhythmia‐related mortality. ICD shock therapy has been shown to increase…”
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