Search Results - "Becker, P.B"
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1
Energy-dependent chromatin accessibility and nucleosome mobility in a cell-free system
Published in The EMBO journal (15-05-1995)“…Chromatin structure must be flexible to allow the binding of regulatory proteins and to accommodate different levels of gene activity. Chromatin assembled in a…”
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2
Transcriptional repression by nucleosomes but not H1 in reconstituted preblastoderm Drosophila chromatin
Published in The EMBO journal (15-01-1994)“…Chromatin reconstituted in an extract from preblastoderm Drosophila embryos represses transcription by RNA polymerase II. We have assembled regularly spaced…”
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3
Functional integration of the histone acetyltransferase MOF into the dosage compensation complex
Published in The EMBO journal (02-06-2004)“…Dosage compensation in flies involves doubling the transcription of genes on the single male X chromosome to match the combined expression level of the two…”
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4
The Chromatin Accessibility Complex: Chromatin Dynamics through Nucleosome Sliding
Published in Cold Spring Harbor Symposia on Quantitative Biology (01-01-2004)“…Abstract only…”
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5
Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II
Published in Nature (London) (07-08-1997)“…Repressive chromatin structures need to be unravelled to allow DNA-binding proteins access to their target sequences. This de-repression constitutes an…”
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Patterns and significance of exhaled-breath biomarkers in lung transplant recipients with acute allograft rejection
Published in The Journal of heart and lung transplantation (01-11-2001)“…Obliterative bronchiolitis (OB) remains one of the leading causes of death in lung transplant recipients after 2 years, and acute rejection (AR) of lung…”
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Translational control of dosage compensation in Drosophila by Sex-lethal: cooperative silencing via the 5' and 3' UTRs of msl-2 mRNA is independent of the poly(A) tail
Published in The EMBO journal (01-11-1999)“…Translational repression of male‐specific‐lethal 2 (msl‐2) mRNA by Sex‐lethal (SXL) controls dosage compensation in Drosophila. In vivo regulation involves…”
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8
Association and spreading of the Drosophila dosage compensation complex from a discrete roX1 chromatin entry site
Published in The EMBO journal (01-05-2001)“…In Drosophila, dosage compensation is controlled by the male‐specific lethal (MSL) complex consisting of MSL proteins and roX RNAs. The MSL complex is…”
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9
Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin
Published in The EMBO journal (15-05-1998)“…A number of activators are known to increase transcription by RNA polymerase (pol) II through protein acetylation. While the physiological substrates for those…”
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10
Chromatin remodeling by GAGA factor and heat shock factor at the hypersensitive Drosophila hsp26 promoter in vitro
Published in The EMBO journal (18-04-1995)“…The chromatin structure at the Drosophila hsp26 promoter in vivo is characterized by two DNase I‐hypersensitive (DH) sites harboring regulatory elements…”
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The chromatin accessibility complex: chromatin dynamics through nucleosome sliding
Published in Cold Spring Harbor Symposia on Quantitative Biology (2004)Get full text
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12
Initiation and bidirectional propagation of chromatin assembly from a target site for nucleotide excision repair
Published in The EMBO journal (15-10-1997)“…To restore full genomic integrity in a eukaryotic cell, DNA repair processes have to be coordinated with the resetting of nucleosomal organization. We have…”
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13
glutamine-rich domain of the Drosophila GAGA factor is necessary for amyloid fibre formation in vitro, but not for chromatin remodelling
Published in Journal of molecular biology (15-01-1999)“…The Drosophila GAGA factor binds specifically to the sequence GAGAG, and synergises with nucleosome remodelling factor to remodel chromatin in vitro. It…”
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14
Analysis of CpG methylation and genomic footprinting at the tyrosine aminotransferase gene: DNA methylation alone is not sufficient to prevent protein binding in vivo
Published in The EMBO journal (01-09-1991)“…Specific DNA sequences from several DNase I hypersensitive sites located upstream of the tyrosine aminotransferase (TAT) gene are bound by ubiquitous nuclear…”
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15
architecture of the heat-inducible Drosophila hsp27 promoter in nuclei
Published in Journal of molecular biology (23-02-1996)“…Transcriptional activation of the Drosophila hsp27 gene in response to heat shock critically relies on binding sites for heat shock factor (HSF) about 300 bp…”
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Dual regulation of the Drosophila hsp26 promoter in vitro
Published in Nucleic acids research (1995)Get full text
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improved protocol for genomic sequencing and footprinting by ligation-mediated PCR
Published in Nucleic acids research (11-06-1993)“…Images…”
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18
Heat shock-regulated transcription in vitro from a reconstituted chromatin template
Published in Proceedings of the National Academy of Sciences - PNAS (15-05-1991)“…To investigate the mechanisms of transcriptional regulation of Drosophila heat shock genes me studied the activity of a heat shock promoter in vitro after…”
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19
Leukaemogenesis in Down's Syndrome
Published in South African medical journal (05-02-1977)“…Due to the fixed karyotype and documented malignancy risk in patients with Down's syndrome, recently descriptionbed aetiological factors can be assigned to…”
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