Search Results - "Becker, Marte A J"

A BET Protein Inhibitor Targeting Mononuclear Myeloid Cells Affects Specific Inflammatory Mediators and Pathways in Crohn’s Disease by Elfiky, Ahmed M. I, Hageman, Ishtu L, Becker, Marte A. J, Verhoeff, Jan, Li Yim, Andrew Y. F, Joustra, Vincent W, Mulders, Lieven, Fung, Ivan, Rioja, Inmaculada, Prinjha, Rab K, Smithers, Nicholas N, Furze, Rebecca C, Mander, Palwinder K, Bell, Matthew J, Buskens, Christianne J, D’Haens, Geert R, Wildenberg, Manon E, de Jonge, Wouter J

“…Background: Myeloid cells are critical determinants of the sustained inflammation in Crohn’s Disease (CD). Targeting such cells may be an effective therapeutic…”
Get full text

Anatomical Variation in Mesenteric Macrophage Phenotypes in Crohn's Disease by van der Meer, Jonathan H.M., Wasmann, Karin A.T.G.M., van der Bilt, Jarmila D.W., Becker, Marte A.J., Boermeester, Marja A., Bemelman, Willem A., Wildenberg, Manon E., Buskens, Christianne J.

“…Clinical trials are currently investigating whether an extended mesenteric resection for ileocecal resections could reduce postoperative recurrence in Crohn's…”
Get full text

Addition of Platelet-Rich Plasma to Endorectal Advancement Flap Repair Does Not Enhance the Healing of Cryptoglandular Transsphincteric Fistulas by Bak, Michiel T J, Arkenbosch, Jeanine H C, Becker, Marte A J, Woude, C Janneke van der, Vries, Annemarie C de, Schouten, W Rudolph, Ruler, Oddeke van

“…The endorectal advancement flap repair is often performed for the treatment of cryptoglandular transsphincteric fistulas. However, this procedure fails in…”
Get full text

Role of the Mesentery in Crohn's Terminal Ileitis by Becker, Marte A J, Does de Willebois, Eline M L van der, Bemelman, Willem A, Wildenberg, Manon E, Buskens, Christianne J

“…Despite the longstanding awareness of the presence of mesenteric alterations in Crohn's disease, the functional and clinical consequences of these alterations…”
Get full text

Short-term anti-TNF therapy with surgical closure versus anti-TNF therapy alone for Crohn's perianal fistulas (PISA-II): long-term outcomes of an international, multicentre patient preference, randomised controlled trial by Meima - van Praag, Elise M., Becker, Marte A.J., van Rijn, Kyra L., Wasmann, Karin A.T.G.M., Stoker, Jaap, D'Haens, Geert R.A.M., Ponsioen, Cyriel Y., Gecse, Krisztina B., Dijkgraaf, Marcel G.W., Spinelli, Antonino, Danese, Silvio, Bemelman, Willem A., Buskens, Christianne J.

“…The PISA-II trial showed that short-term anti-tumour necrosis factor (anti-TNF) therapy followed by surgical closure induces radiological healing of perianal…”
Get full text

Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis by Spaan, Claudia N, de Boer, Ruben J, Smit, Wouter L, van der Meer, Jonathan HM, van Roest, Manon, Vermeulen, Jacqueline LM, Koelink, Pim J, Becker, Marte AJ, Go, Simei, Silva, Joana, Faller, William J, van den Brink, Gijs R, Muncan, Vanesa, Heijmans, Jarom

“…In development of colorectal cancer, mutations in APC are often followed by mutations in oncogene KRAS . The latter changes cellular metabolism and is…”
Get full text