Search Results - "Becker, Lea Marie"
-
1
NMR-derived secondary structure of the full-length Ox40 mRNA 3′UTR and its multivalent binding to the immunoregulatory RBP Roquin
Published in Nucleic acids research (22-04-2022)“…Abstract Control of posttranscriptional mRNA decay is a crucial determinant of cell homeostasis and differentiation. mRNA lifetime is governed by…”
Get full text
Journal Article -
2
Teixobactin kills bacteria by a two-pronged attack on the cell envelope
Published in Nature (London) (11-08-2022)“…Antibiotics that use novel mechanisms are needed to combat antimicrobial resistance 1 – 3 . Teixobactin 4 represents a new class of antibiotics with a unique…”
Get full text
Journal Article -
3
Aromatic ring flips in differently packed ubiquitin protein crystals from MAS NMR and MD
Published in Journal of structural biology. X (01-01-2023)“…[Display omitted] •A specific isotope labeling scheme and fast magic-angle spinning NMR provide insight into ring flips.•One of the two phenylalanines, Phe4,…”
Get full text
Journal Article -
4
Protein dynamics detected by magic-angle spinning relaxation dispersion NMR
Published in Current opinion in structural biology (01-10-2023)“…Magic-angle spinning (MAS) nuclear magnetic resonance (NMR) is establishing itself as a powerful method for the characterization of protein dynamics at the…”
Get full text
Journal Article -
5
NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin
Published in Nucleic acids research (22-04-2022)“…Control of posttranscriptional mRNA decay is a crucial determinant of cell homeostasis and differentiation. mRNA lifetime is governed by cis-regulatory…”
Get full text
Journal Article -
6
The Rigid Core and Flexible Surface of Amyloid Fibrils Probed by Magic‐Angle‐Spinning NMR Spectroscopy of Aromatic Residues
Published in Angewandte Chemie International Edition (02-05-2023)“…Aromatic side chains are important reporters of the plasticity of proteins, and often form important contacts in protein–protein interactions. We studied…”
Get full text
Journal Article -
7
Cover Picture: The Rigid Core and Flexible Surface of Amyloid Fibrils Probed by Magic‐Angle‐Spinning NMR Spectroscopy of Aromatic Residues (Angew. Chem. Int. Ed. 19/2023)
Published in Angewandte Chemie International Edition (02-05-2023)“…Rock‐solid amyloid?. Aromatic residues in the core of the amyloid fibrils HELLF and HET‐s show no sign of ring flips suggesting a rigid core that does not…”
Get full text
Journal Article -
8
The rigid core and flexible surface of amyloid fibrils probed by Magic‐Angle Spinning NMR of aromatic residues
Published in Angewandte Chemie International Edition (04-02-2023)“…Dedicated to Robert Konrat, on the occasion of his 60th birthday. Aromatic side chains are important reporters of the plasticity of proteins, and often form…”
Get full text
Journal Article -
9
Evaluating the motional timescales contributing to averaged anisotropic interactions in MAS solid-state NMR
Published in Magnetic Resonance : (Göttingen) (01-06-2024)“…Dynamic processes in molecules can occur on a wide range of timescales, and it is important to understand which timescales of motion contribute to different…”
Get full text
Journal Article -
10
Titelbild: Der starre Kern und die flexible Oberfläche von Amyloidfibrillen – Magic‐Angle‐Spinning NMR Spektroskopie von aromatischen Resten (Angew. Chem. 19/2023)
Published in Angewandte Chemie (02-05-2023)“…Rock‐solid amyloid?. Aromatic residues in the core of the amyloid fibrils HELLF and HET‐s show no sign of ring flips suggesting a rigid core that does not…”
Get full text
Journal Article -
11
Der starre Kern und die flexible Oberfläche von Amyloidfibrillen – Magic‐Angle‐Spinning NMR Spektroskopie von aromatischen Resten
Published in Angewandte Chemie (02-05-2023)“…Aromatische Seitenketten sind wichtige Indikatoren für die Plastizität von Proteinen und bilden oft entscheidende Kontakte bei…”
Get full text
Journal Article -
12
Aromatic ring flips in differently packed ubiquitin protein crystals from MAS NMR and MD
Published in Journal of structural biology. X (2023)“…Probing the dynamics of aromatic side chains provides important insights into the behavior of a protein because flips of aromatic rings in a protein’s…”
Get full text
Journal Article -
13
Der starre Kern und die flexible Oberfläche von Amyloidfibrillen – Magic‐Angle‐Spinning NMR Spektroskopie von aromatischen Resten
Published in Angewandte Chemie (02-05-2023)“…Aromatische Seitenketten sind wichtige Indikatoren für die Plastizität von Proteinen und bilden oft entscheidende Kontakte bei…”
Get full text
Journal Article