Search Results - "Becker, Ina"
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The Influence of Radiation on Bone and Bone Cells-Differential Effects on Osteoclasts and Osteoblasts
Published in International journal of molecular sciences (02-09-2020)“…The bone is a complex organ that is dependent on a tight regulation between bone formation by osteoblasts (OBs) and bone resorption by osteoclasts (OCs). These…”
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Agrobacterium tumefaciens-Mediated Nuclear Transformation of a Biotechnologically Important Microalga—Euglena gracilis
Published in International journal of molecular sciences (11-06-2021)“…Euglena gracilis (E. gracilis) is an attractive organism due to its evolutionary history and substantial potential to produce biochemicals of commercial…”
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Prospective development and validation of a liquid immune profile-based signature (LIPS) to predict response of patients with recurrent/metastatic cancer to immune checkpoint inhibitors
Published in Journal for immunotherapy of cancer (01-02-2021)“…BackgroundThe predictive power of novel biological markers for treatment response to immune checkpoint inhibitors (ICI) is still not satisfactory for the…”
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Effects of serial radon spa therapy on pain and peripheral immune status in patients suffering from musculoskeletal disorders- results from a prospective, randomized, placebo-controlled trial
Published in Frontiers in immunology (06-02-2024)“…In this randomized, placebo-controlled cross-over trial we aimed to investigate if radon spa therapy exerts more pain relief than exposure to warm water alone…”
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Machine Learning-assisted immunophenotyping of peripheral blood identifies innate immune cells as best predictor of response to induction chemo-immunotherapy in head and neck squamous cell carcinoma – knowledge obtained from the CheckRad-CD8 trial
Published in Neoplasia (New York, N.Y.) (01-03-2024)“…•Peripheral blood immune parameters predict efficacy of chemoimmunotherapy in HNSCC.•Various differences of immune parameters before and after treatment…”
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Safety and efficacy of single cycle induction treatment with cisplatin/docetaxel/ durvalumab/tremelimumab in locally advanced HNSCC: first results of CheckRad-CD8
Published in Journal for immunotherapy of cancer (01-10-2020)“…BackgroundTo determine safety and efficacy of single cycle induction treatment with cisplatin/docetaxel and durvalumab/tremelimumab in stage III-IVB head and…”
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Low Dose Radiation Therapy Induces Long-Lasting Reduction of Pain and Immune Modulations in the Peripheral Blood - Interim Analysis of the IMMO-LDRT01 Trial
Published in Frontiers in immunology (12-10-2021)“…The treatment of chronic inflammatory and degenerative diseases by low dose radiation therapy (LDRT) is promising especially for patients who were refractory…”
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Modulation of Differentiation and Bone Resorbing Activity of Human (Pre-) Osteoclasts After X-Ray Exposure
Published in Frontiers in immunology (04-05-2022)“…Low-dose radiotherapy (LD-RT) is a local treatment option for patients with chronic degenerative and inflammatory diseases, in particular musculoskeletal…”
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Corrigendum: Low Dose Radiation Therapy Induces Long-Lasting Reduction of Pain and Immune Modulations in the Peripheral Blood - Interim Analysis of the IMMO-LDRT01 Trial
Published in Frontiers in immunology (07-02-2022)“…[This corrects the article DOI: 10.3389/fimmu.2021.740742.]…”
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Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in locally advanced head and neck cancer
Published in Journal for immunotherapy of cancer (01-01-2022)“…PurposeThe first aim of the trial is to study feasibility of combined programmed death protein ligand 1/cytotoxic T-lymphocyte-associated protein 4 inhibition…”
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Prospective Evaluation of CD45RA+/CCR7- Effector Memory T (T EMRA ) Cell Subsets in Patients with Primary and Secondary Brain Tumors during Radiotherapy of the Brain within the Scope of the Prospective Glio-CMV-01 Clinical Trial
Published in Cells (Basel, Switzerland) (01-02-2023)“…Radiotherapy (RT) of the brain is a common treatment for patients with high-grade gliomas and brain metastases. It has previously been shown that reactivation…”
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The Emergency Psychiatric Interview
Published in Emergency medicine clinics of North America (01-02-2024)“…A quality clinical interview helps establish a good collaborative relationship with the patient. This is especially important when emergency physicians conduct…”
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Workplace Interventions to Reduce Sedentary Behavior: A Systematic Review
Published in Gesundheitswesen (Bundesverband der Ärzte des Öffentlichen Gesundheitsdienstes (Germany)) (01-08-2019)“…Sedentary behaviour is a health risk factor independent of physical activity. Interventions that aim to reduce sitting at the workplace are particularly…”
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3D-Shaped Binders of Unfolded Proteins Inducing Cancer Cell-Specific Endoplasmic Reticulum Stress In Vitro and In Vivo
Published in Journal of the American Chemical Society (11-10-2023)“…The amount of unfolded proteins is increased in cancer cells, leading to endoplasmic reticulum (ER) stress. Therefore, cancer cells are sensitive to drugs…”
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Eu:CROPIS – “Euglena gracilis: Combined Regenerative Organic-food Production in Space” - A Space Experiment Testing Biological Life Support Systems Under Lunar And Martian Gravity
Published in Microgravity science and technology (01-12-2018)“…Human space exploration needs stable life support systems for the supply of oxygen, water and food for each human explorer due to long term missions. The most…”
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Temporarily increased TGFβ following radon spa correlates with reduced pain while serum IL-18 is a general predictive marker for pain sensitivity
Published in Radiation and environmental biophysics (01-03-2019)“…Sustained pain relief following radon spa therapy in patients suffering from chronic painful diseases has been well described. But still, the underlying…”
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The origins of electroconvulsive therapy: Prof. Bini's first report on ECT
Published in Journal of affective disorders (01-01-2010)“…Abstract In August 1939, at the 3rd International Neurological Congress in Copenhagen, Professor Lucio Bini reported on the first use of electricity to induce…”
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Analysis of the immune status from peripheral whole blood with a single-tube multicolor flow cytometry assay
Published in Methods in enzymology (2020)“…Supplementation of standard cancer therapies (radiotherapy, chemotherapy, surgery) with immunotherapies has revolutionized cancer treatment. In order to…”
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Transcriptomes of MPO-Deficient Patients with Generalized Pustular Psoriasis Reveals Expansion of CD4 + Cytotoxic T Cells and an Involvement of the Complement System
Published in Journal of investigative dermatology (30-12-2021)“…Generalized pustular psoriasis is a severe psoriatic subtype characterized by epidermal neutrophil infiltration. Although variants in IL36RN and MPO have been…”
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