Search Results - "Becker, Alyssa B"
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The pathogenesis of cardiomyopathy in Friedreich ataxia
Published in PloS one (04-03-2015)“…Friedreich ataxia (FA) is an autosomal recessive disease with a complex neurological phenotype, but the most common cause of death is heart failure. This study…”
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Abundance and Significance of Iron, Zinc, Copper, and Calcium in the Hearts of Patients with Friedreich Ataxia
Published in The American journal of cardiology (01-07-2016)“…Abstract Cardiomyopathy is a frequent cause of death in patients with Friedreich ataxia (FA), and a characteristic pathological feature is the focal…”
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Pathology of Intercalated Discs in Friedreich Cardiomyopathy
Published in Journal of the American College of Cardiology (13-10-2015)Get full text
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4
Friedreich Ataxia: Hypoplasia of Spinal Cord and Dorsal Root Ganglia
Published in Journal of neuropathology and experimental neurology (01-02-2017)“…After Friedreich's description in 1877, depletion of myelinated fibers in the dorsal columns, dorsal spinocerebellar and lateral corticospinal tracts, and…”
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Friedreich Ataxia: Developmental Failure of the Dorsal Root Entry Zone
Published in Journal of neuropathology and experimental neurology (01-11-2017)“…Abstract Dorsal root ganglia, dorsal roots (DR), and dorsal root entry zones (DREZ) are vulnerable to frataxin deficiency in Friedreich ataxia (FA). A…”
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Contrast-Enhanced Ultrasound of Mouse Models of Hindlimb Ischemia Reveals Persistent Perfusion Deficits and Distinctive Muscle Perfusion Patterns
Published in Ultrasound in medicine & biology (01-01-2025)“…Mouse models of hindlimb ischemia (HLI) are used to study peripheral arterial disease and evaluate novel therapies. Contrast-enhanced ultrasound (CEUS) is a…”
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Contrast-Enhanced Ultrasound Reveals Partial Perfusion Recovery After Hindlimb Ischemia as Opposed to Full Recovery by Laser Doppler Perfusion Imaging
Published in Ultrasound in medicine & biology (01-06-2022)“…Mouse models are critical in developing new therapeutic approaches to treat peripheral arterial disease (PAD). Despite decades of research and numerous…”
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Heart and Nervous System Pathology in Compound Heterozygous Friedreich Ataxia
Published in Journal of neuropathology and experimental neurology (01-08-2017)“…In a small percentage of patients with Friedreich ataxia (FA), the pathogenic mutation is compound heterozygous, consisting of a guanine-adenine-adenine (GAA)…”
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Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation
Published in Acta neuropathologica communications (03-05-2016)“…Dorsal root ganglia (DRG) are highly vulnerable to frataxin deficiency in Friedreich ataxia (FA), an autosomal recessive disease due to pathogenic homozygous…”
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Friedreich Ataxia: Failure of GABA-ergic and Glycinergic Synaptic Transmission in the Dentate Nucleus
Published in Journal of neuropathology and experimental neurology (01-02-2015)“…ABSTRACTAtrophy of large neurons in the dentate nucleus (DN) is an important pathologic correlate of neurologic disability in patients with Friedreich ataxia…”
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The significance of intercalated discs in the pathogenesis of Friedreich cardiomyopathy
Published in Journal of the neurological sciences (15-08-2016)“…Abstract Friedreich ataxia (FRDA) is an autosomal recessive disorder with a complex clinical and neuropathological phenotype, but the most frequent cause of…”
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Contrast-Enhanced Ultrasound of Mouse Models of Hindlimb Ischemia Reveals Persistent Perfusion Deficits and Distinctive Muscle Perfusion Patterns
Published in Ultrasound in medicine & biology (18-10-2024)“…Mouse models of hindlimb ischemia (HLI) are used to study peripheral arterial disease and evaluate novel therapies. Contrast-enhanced ultrasound (CEUS) is a…”
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13
Friedreich Ataxia
Published in Journal of neuropathology and experimental neurology (01-02-2015)“…Atrophy of large neurons in the dentate nucleus (DN) is an important pathologic correlate of neurologic disability in patients with Friedreich ataxia (FA)…”
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Abstract 16003: Contrast Enhanced Ultrasound Detects Sustained Reductions in Perfusion and Differential Patterns of Muscle Perfusion in Surgical Mouse Models of Hindlimb Ischemia
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionMouse models of hindlimb ischemia (HLI) are used to explore therapies for peripheral artery disease (PAD). Degrees of ischemia can be induced by…”
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