Search Results - "Bechi, Beatrice"

Amines Bearing Tertiary Substituents by Tandem Enantioselective Carbolithiation–Rearrangement of Vinylureas by Tait, Michael, Donnard, Morgan, Minassi, Alberto, Lefranc, Julien, Bechi, Beatrice, Carbone, Giorgio, O’Brien, Peter, Clayden, Jonathan

“…In the presence of (−)-sparteine or a (+)-sparteine surrogate, organolithiums add to N-alkenyl-N′-arylureas to give benzylic organolithiums in an…”
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Stereocontrolled synthesis of 5-azaspiro[2.3]hexane derivatives as conformationally "frozen" analogues of L-glutamic acid by Bechi, Beatrice, Amantini, David, Tintori, Cristina, Botta, Maurizio, Fabio, Romano di

“…Several strategies aimed to "freeze" natural amino acids into more constrained analogues have been developed with the aim of enhancing in vitro…”
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Development of an R-Selective Amine Oxidase with Broad Substrate Specificity and High Enantioselectivity by Heath, Rachel S., Pontini, Marta, Bechi, Beatrice, Turner, Nicholas J.

“…Amine oxidases are useful bio‐catalysts for the synthesis of enantiomerically pure 1°, 2° and 3° chiral amines. Enzymes in this class (e.g., MAO‐N from…”
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Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: Part 2. Synthesis of rigid pyrazolones by Castagnolo, Daniele, Manetti, Fabrizio, Radi, Marco, Bechi, Beatrice, Pagano, Mafalda, De Logu, Alessandro, Meleddu, Rita, Saddi, Manuela, Botta, Maurizio

“…Two series of novel rigid pyrazolone derivatives were synthesized and evaluated as inhibitors of Mycobacterium tuberculosis (MTB), the causative agent of…”
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Microwave-assisted organocatalytic multicomponent Knoevenagel/hetero Diels–Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles by Radi, Marco, Bernardo, Vincenzo, Bechi, Beatrice, Castagnolo, Daniele, Pagano, Mafalda, Botta, Maurizio

“…A rapid protocol for the multicomponent microwave-assisted organocatalytic Knoevenagel/hetero Diels–Alder reaction (KHDA) has been developed. A rapid protocol…”
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Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy by Bennett, Ailsa, Bechi, Beatrice, Tighe, Anthony, Thompson, Sarah, Procter, David J, Taylor, Stephen S

“…Aneuploidy is a common feature of cancer, with human solid tumour cells typically harbouring abnormal chromosome complements. The aneuploidy observed in cancer…”
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Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis by Castagnolo, Daniele, De Logu, Alessandro, Radi, Marco, Bechi, Beatrice, Manetti, Fabrizio, Magnani, Matteo, Supino, Sibilla, Meleddu, Rita, Chisu, Lorenza, Botta, Maurizio

“…As a continuation of our previous work that turned toward the identification of antimycobacterial compounds with innovative structures, two series of pyrazole…”
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Stereoselective Monoamine Oxidase-Catalyzed Oxidative Aza-Friedel-Crafts Reactions of meso-Pyrrolidines in Aqueous Buffer by de Graaff, Corien, Oppelaar, Barry, Péruch, Olivier, Vande Velde, Christophe M. L., Bechi, Beatrice, Turner, Nicholas J., Ruijter, Eelco, Orru, Romano V. A.

“…We disclose the highly diastereoselective combination of monoamine oxidase‐catalyzed oxidation of meso‐pyrrolidines and aza‐Friedel–Crafts reactions in aqueous…”
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MYC Is a Major Determinant of Mitotic Cell Fate by Topham, Caroline, Tighe, Anthony, Ly, Peter, Bennett, Ailsa, Sloss, Olivia, Nelson, Louisa, Ridgway, Rachel A., Huels, David, Littler, Samantha, Schandl, Claudia, Sun, Ying, Bechi, Beatrice, Procter, David J., Sansom, Owen J., Cleveland, Don W., Taylor, Stephen S.

“…Taxol and other antimitotic agents are frontline chemotherapy agents but the mechanisms responsible for patient benefit remain unclear. Following a genome-wide…”
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Amines Bearing Tertiary Substituents by Tandem Enantioselective Carbolithiation–Rearrangement of Vinylureas by Tait, Michael, Donnard, Morgan, Minassi, Alberto, Lefranc, Julien, Bechi, Beatrice, Carbone, Giorgio, O’Brien, Peter, Clayden, Jonathan

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Inside Back Cover: Development of an R-Selective Amine Oxidase with Broad Substrate Specificity and High Enantioselectivity (ChemCatChem 4/2014) by Heath, Rachel S., Pontini, Marta, Bechi, Beatrice, Turner, Nicholas J.

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