Search Results - "Becerra, Arturo"

Evolutionary convergence in the biosyntheses of the imidazole moieties of histidine and purines by Vázquez-Salazar, Alberto, Becerra, Arturo, Lazcano, Antonio

“…The imidazole group is an ubiquitous chemical motif present in several key types of biomolecules. It is a structural moiety of purines, and plays a central…”
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Sofosbuvir as a potential alternative to treat the SARS-CoV-2 epidemic by Jácome, Rodrigo, Campillo-Balderas, José Alberto, Ponce de León, Samuel, Becerra, Arturo, Lazcano, Antonio

“…As of today, there is no antiviral for the treatment of the SARS-CoV-2 infection, and the development of a vaccine might take several months or even years. The…”
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Structural Analysis of Monomeric RNA-Dependent Polymerases: Evolutionary and Therapeutic Implications by Jácome, Rodrigo, Becerra, Arturo, Ponce de León, Samuel, Lazcano, Antonio

“…The crystal structures of monomeric RNA-dependent RNA polymerases and reverse transcriptases of more than 20 different viruses are available in the Protein…”
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The Role of Gene Duplication in the Divergence of Enzyme Function: A Comparative Approach by Álvarez-Lugo, Alejandro, Becerra, Arturo

“…Gene duplication is a crucial process involved in the appearance of new genes and functions. It is thought to have played a major role in the growth of enzyme…”
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Molecular Evolution of the Oxygen-Binding Hemerythrin Domain by Alvarez-Carreño, Claudia, Becerra, Arturo, Lazcano, Antonio

“…The evolution of oxygenic photosynthesis during Precambrian times entailed the diversification of strategies minimizing reactive oxygen species-associated…”
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Comparative evaluation of bioinformatic tools for virus-host prediction and their application to a highly diverse community in the Cuatro Ciénegas Basin, Mexico by Cisneros-Martínez, Alejandro Miguel, Rodriguez-Cruz, Ulises E, Alcaraz, Luis D, Becerra, Arturo, Eguiarte, Luis E, Souza, Valeria

“…Due to the enormous diversity of non-culturable viruses, new viruses must be characterized using culture-independent techniques. The associated host is an…”
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Repetitive DNA profile of the amphibian mitogenome by Cabañas, Noel, Becerra, Arturo, Romero, David, Govezensky, Tzipe, Espinosa-Aguirre, Jesús Javier, Camacho-Carranza, Rafael

“…Repetitive DNA elements such as direct and inverted repeat sequences are present in every genome, playing numerous biological roles. In amphibians, the…”
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Structural analysis of viral ExoN domains reveals polyphyletic hijacking events by Cruz-González, Adrián, Muñoz-Velasco, Israel, Cottom-Salas, Wolfgang, Becerra, Arturo, Campillo-Balderas, José A, Hernández-Morales, Ricardo, Vázquez-Salazar, Alberto, Jácome, Rodrigo, Lazcano, Antonio

“…Nidoviruses and arenaviruses are the only known RNA viruses encoding a 3'-5' exonuclease domain (ExoN). The proofreading activity of the ExoN domain has played…”
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Two short low complexity regions (LCRs) are hallmark sequences of the Delta SARS-CoV-2 variant spike protein by Becerra, Arturo, Muñoz-Velasco, Israel, Aguilar-Cámara, Abelardo, Cottom-Salas, Wolfgang, Cruz-González, Adrián, Vázquez-Salazar, Alberto, Hernández-Morales, Ricardo, Jácome, Rodrigo, Campillo-Balderas, José Alberto, Lazcano, Antonio

“…Low complexity regions (LCRs) are protein sequences formed by a set of compositionally biased residues. LCRs are extremely abundant in cellular proteins and…”
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Holocene life and microbiome profiling in ancient tropical Lake Chalco, Mexico by Moguel, Bárbara, Pérez, Liseth, Alcaraz, Luis D., Blaz, Jazmín, Caballero, Margarita, Muñoz-Velasco, Israel, Becerra, Arturo, Laclette, Juan P., Ortega-Guerrero, Beatriz, Romero-Oliva, Claudia S., Herrera-Estrella, Luis, Lozano-García, Socorro

“…Metagenomic and traditional paleolimnological approaches are suitable to infer past biological and environmental changes, however, they are often applied…”
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The Very Early Stages of Biological Evolution and the Nature of the Last Common Ancestor of the Three Major Cell Domains by Becerra, Arturo, Delaye, Luis, Islas, Sara, Lazcano, Antonio

“…Quantitative estimates of the gene complement of the last common ancestor of all extant organisms, that is, the cenancestor, may be hindered by ancient…”
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Norvaline and Norleucine May Have Been More Abundant Protein Components during Early Stages of Cell Evolution by Alvarez-Carreño, Claudia, Becerra, Arturo, Lazcano, Antonio

“…The absence of the hydrophobic norvaline and norleucine in the inventory of protein amino acids is readdressed. The well-documented intracellular accumulation…”
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Subtle structural differences of nucleotide analogs may impact SARS-CoV-2 RNA-dependent RNA polymerase and exoribonuclease activity by Madariaga-Mazón, Abraham, Naveja, José J., Becerra, Arturo, Alberto Campillo-Balderas, José, Hernández-Morales, Ricardo, Jácome, Rodrigo, Lazcano, Antonio, Martinez-Mayorga, Karina

“…[Display omitted] The rapid spread and public health impact of the novel SARS-CoV-2 variants that cause COVID-19 continue to produce major global impacts and…”
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The origin of a novel gene through overprinting in Escherichia coli by Delaye, Luis, Deluna, Alexander, Lazcano, Antonio, Becerra, Arturo

“…Overlapped genes originate by a) loss of a stop codon among contiguous genes coded in different frames; b) shift to an upstream initiation codon of one of the…”
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The Semi-Enzymatic Origin of Metabolic Pathways: Inferring a Very Early Stage of the Evolution of Life by Becerra, Arturo

“…The early evolution of life is a period with many important events with a lot of big and open questions. One of them is the evolution of metabolic pathways,…”
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Protein Disulfide Oxidoreductases and the Evolution of Thermophily: Was the Last Common Ancestor a Heat-Loving Microbe by Becerra, Arturo, Delaye, Luis, Lazcano, Antonio, Orgel, Leslie E

“…Protein disulfide oxidoreductases (PDOs) are redox enzymes that catalyze dithiol-disulfide exchange reactions. Their sequences and structure reveal the…”
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RNA or DNA? Revisiting the Chemical Nature of the Cenancestral Genome by Cottom-Salas, Wolfgang, Becerra, Arturo, Lazcano, Antonio

“…One of the central issues in the understanding of early cellular evolution is the characterisation of the cenancestor. This includes the description of the…”
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La reconstrucción inacabada del ancestro universal by Arturo Becerra, Luis Delaye

“…El cenancestro se define como el último ancestro común de todos los seres vivos que existen actualmente. Su naturaleza se ha inferido a partir de la…”
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A New View of the Last Universal Common Ancestor by Goldman, Aaron D., Becerra, Arturo

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Introduction to the Special Issue on Early Evolution and the Last Common Ancestor by Becerra, Arturo, Goldman, Aaron D.

“…The early evolution of life spans an extensive period preceding the emergence of the first eukaryotic cell. This epoch, which transpired from 4.5 to 2.5…”
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