Search Results - "Beccari, S"
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Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration
Published in Nature neuroscience (01-02-2019)“…Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are associated with loss of nuclear transactive response DNA-binding protein 43 (TDP-43)…”
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Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain
Published in Nature communications (30-11-2020)“…Omega-3 fatty acids (n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and developing…”
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3
Stem cells for amyotrophic lateral sclerosis modeling and therapy: Myth or fact?
Published in Cytometry. Part A (01-03-2015)“…Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease whose pathophysiology is poorly understood. Aiming to better understand the…”
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On the FE codes capability for tool temperature calculation in machining processes
Published in Journal of materials processing technology (25-05-2006)“…The applications of numerical simulation to machining processes have been more and more growing in the last years: today a quite effective predictive…”
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5
PDX-1 (pancreatic/duodenal homeobox-1 protein 1)
Published in Pathologica (01-12-2014)“…The homeodomain-containing transcription factor pancreatic duodenal homeobox 1 (PDX-1) plays a key role in pancreatic development and β-cell function. It is a…”
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HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells
Published in Science (American Association for the Advancement of Science) (05-02-2021)“…The RNA binding protein TDP-43 forms intranuclear or cytoplasmic aggregates in age-related neurodegenerative diseases. In this study, we found that RNA…”
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Pathological complete response in a patient affected by multiple synchronous, breast and lung primary malignancies: a case report and review of the literature
Published in Pathologica (01-12-2016)“…A pathological complete response in a patient affected by multiple synchronous, breast and lung primary malignancies is reported. A 63-year-old woman presented…”
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Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies
Published in Science (American Association for the Advancement of Science) (17-03-2023)“…Loss of nuclear TDP-43 is a hallmark of neurodegeneration in TDP-43 proteinopathies, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia…”
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Ependymoma with diffuse signet-ring features: report of a case and review of the literature
Published in Pathologica (01-03-2016)“…Signet-ring cell ependymoma is a rare variant of ependymoma with only seven cases described in literature. Biological behavior and prognosis of this entity are…”
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Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation
Published in Nature neuroscience (01-01-2024)“…The mRNA transcript of the human STMN2 gene, encoding for stathmin-2 protein (also called SCG10), is profoundly impacted by TAR DNA-binding protein 43 (TDP-43)…”
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Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease
Published in Acta neuropathologica (01-06-2024)“…Nuclear clearance and cytoplasmic accumulations of the RNA-binding protein TDP-43 are pathological hallmarks in almost all patients with amyotrophic lateral…”
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Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy
Published in Autophagy (03-07-2023)“…Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neurons and inflammatory responses. Whereas microglia are very competent…”
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Guidance of Cell Migration by the Drosophila PDGF/VEGF Receptor
Published in Cell (05-10-2001)“…Directed cell migrations are important for development, but the signaling pathways and mechanisms responsible for guiding cell migration in vivo are poorly…”
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Designer Peptide Antagonist of the Leptin Receptor with Peripheral Antineoplastic Activity
Published in Annals of oncology (01-09-2012)Get full text
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483P - Designer Peptide Antagonist of the Leptin Receptor with Peripheral Antineoplastic Activity
Published in Annals of oncology (01-09-2012)“…Obesity-related hormone leptin has been implicated in the development and progression of different cancer types. Studies in vitro and animal models documented…”
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PIPPin is a brain-specific protein that contains a cold-shock domain and binds specifically to H1 degrees and H3.3 mRNAs
Published in The Journal of biological chemistry (20-08-1999)“…During maturation of mammalian brain, variants of both linker (i.e. H1 degrees) and core (i.e. H3.3) histone proteins accumulate in nerve cells. As the…”
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The JAK/STAT pathway is required for border cell migration during Drosophila oogenesis
Published in Mechanisms of development (01-02-2002)“…During Drosophila oogenesis, border cells perform a stereotypic migration. Slbo, a C/EBP transcription factor, is required for this migration. Here we identify…”
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Specific neurons of brain cortex and cerebellum are PIPPin positive
Published in Neuroreport (14-07-2000)“…We recently cloned a cDNA encoding an RNA-binding protein, that we called PIPPin, which is highly enriched in the rat brain and contains two putative double…”
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PIPPin Is a Brain-specific Protein That Contains a Cold-shock Domain and Binds Specifically to H1 degree and H3.3 mRNAs
Published in The Journal of biological chemistry (20-08-1999)“…During maturation of mammalian brain, variants of both linker (i.e. H1 degree ) and core (i.e. H3.3) histone proteins accumulate in nerve cells. As the…”
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Extraoral traction with face-bow: evaluation of the action of the intraoral arch
Published in Mondo ortodontico (01-09-1988)Get more information
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