Search Results - "Beaver, A"

The Wild West of Checkpoint Inhibitor Development by Beaver, Julia A, Pazdur, Richard

“…Although immunotherapy development has improved overall survival among patients with common cancers and has led to important therapeutic advances, rapid…”
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Reevaluating Eligibility Criteria — Balancing Patient Protection and Participation in Oncology Trials by Beaver, Julia A, Ison, Gwynn, Pazdur, Richard

“…Specific patient populations are often excluded from oncology trials without clear reasons, which renders results less clearly applicable to all patients. A…”
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FDA Approval Summary: Sotorasib for KRAS G12C-Mutated Metastatic NSCLC by Nakajima, Erica C, Drezner, Nicole, Li, Xiaoxue, Mishra-Kalyani, Pallavi S, Liu, Yajun, Zhao, Hong, Bi, Youwei, Liu, Jiang, Rahman, Atiqur, Wearne, Emily, Ojofeitimi, Idara, Hotaki, Lauren Tesh, Spillman, Dianne, Pazdur, Richard, Beaver, Julia A, Singh, Harpreet

“…On May 28, 2021, the FDA granted accelerated approval to sotorasib (Lumakras, Amgen) for the treatment of adults with advanced non-small cell lung cancer…”
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Reassessment of the Species in the Euwallacea Fornicatus (Coleoptera: Curculionidae: Scolytinae) Complex after the Rediscovery of the "Lost" Type Specimen by M Smith, Sarah, F Gomez, Demian, A Beaver, Roger, Hulcr, Jiri, I Cognato, Anthony

“…Ambrosia beetles of the (Eichhoff, 1868) species complex are emerging tree pests, responsible for significant damage to orchards and ecosystems around the…”
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Analysis of the Association Between Adverse Events and Outcome in Patients Receiving a Programmed Death Protein 1 or Programmed Death Ligand 1 Antibody by Maher, V Ellen, Fernandes, Laura L, Weinstock, Chana, Tang, Shenghui, Agarwal, Sundeep, Brave, Michael, Ning, Yang-Min, Singh, Harpreet, Suzman, Daniel, Xu, James, Goldberg, Kirsten B, Sridhara, Rajeshwari, Ibrahim, Amna, Theoret, Marc, Beaver, Julia A, Pazdur, Richard

“…To assess the relationship among tumor response rate, overall survival, and the development of related adverse events of special interest (AESIs) or related…”
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FDA Approval Summary: Pembrolizumab for the Treatment of Tumor Mutational Burden-High Solid Tumors by Marcus, Leigh, Fashoyin-Aje, Lola A, Donoghue, Martha, Yuan, Mengdie, Rodriguez, Lisa, Gallagher, Pamela S, Philip, Reena, Ghosh, Soma, Theoret, Marc R, Beaver, Julia A, Pazdur, Richard, Lemery, Steven J

“…The FDA approved pembrolizumab on June 16, 2020, for the treatment of adult and pediatric patients with unresectable or metastatic tumor mutational burden-high…”
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Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement by Kim, Edward S, Bruinooge, Suanna S, Roberts, Samantha, Ison, Gwynn, Lin, Nancy U, Gore, Lia, Uldrick, Thomas S, Lichtman, Stuart M, Roach, Nancy, Beaver, Julia A, Sridhara, Rajeshwari, Hesketh, Paul J, Denicoff, Andrea M, Garrett-Mayer, Elizabeth, Rubin, Eric, Multani, Pratik, Prowell, Tatiana M, Schenkel, Caroline, Kozak, Marina, Allen, Jeff, Sigal, Ellen, Schilsky, Richard L

“…Purpose The primary purposes of eligibility criteria are to protect the safety of trial participants and define the trial population. Excessive or overly…”
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FDA Approval Summary: Pembrolizumab plus Lenvatinib for Endometrial Carcinoma, a Collaborative International Review under Project Orbis by Arora, Shaily, Balasubramaniam, Sanjeeve, Zhang, Wei, Zhang, Lijun, Sridhara, Rajeshwari, Spillman, Dianne, Mathai, Jaigi P, Scott, Bradley, Golding, Sarah J, Coory, Michael, Pazdur, Richard, Beaver, Julia A

“…On September 17, 2019, FDA granted accelerated approval to pembrolizumab plus lenvatinib for the treatment of patients with advanced endometrial carcinoma that…”
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US Food and Drug Administration Approval Summary: Nivolumab Plus Platinum-Doublet Chemotherapy for the Neoadjuvant Treatment of Patients With Resectable Non-Small-Cell Lung Cancer by Akinboro, Oladimeji, Drezner, Nicole, Amatya, Anup, Runyan, Jin, Fourie-Zirkelbach, Jeanne, Zhao, Miao, Bi, Youwei, Korsah, Kwadwo, Mixter, Bronwyn, Tang, Shenghui, Larkins, Erin, Pazdur, Richard, Beaver, Julia A, Singh, Harpreet

“…On March 4, 2022, the US Food and Drug Administration (FDA) approved nivolumab plus platinum-doublet chemotherapy for the neoadjuvant treatment of patients…”
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Effects of a synthetic analogue of the bovine appeasing pheromone on the overall welfare of dairy calves from birth through weaning by Garcia-Alvarez, J., Teruel, E., Cozzi, A., Harris, E., Rutter, S.M., Beaver, A.

“…Environmental enrichment in the form of synthetic analogs of appeasing pheromones have shown promising results in improving the welfare of domestic animals…”
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FDA Approval Summary: Accelerated Approval of Sacituzumab Govitecan-hziy for Third-line Treatment of Metastatic Triple-negative Breast Cancer by Wahby, Sakar, Fashoyin-Aje, Lola, Osgood, Christy L, Cheng, Joyce, Fiero, Mallorie H, Zhang, Lijun, Tang, Shenghui, Hamed, Salaheldin S, Song, Pengfei, Charlab, Rosane, Dorff, Sarah E, Ricks, Tiffany K, Barnett-Ringgold, Kimberly, Dinin, Jeannette, Goldberg, Kirsten B, Theoret, Marc R, Pazdur, Richard, Amiri-Kordestani, Laleh, Beaver, Julia A

“…On April 22, 2020, the FDA granted accelerated approval to sacituzumab govitecan-hziy (TRODELVY; Immunomedics, Inc.) for the treatment of patients with…”
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Systematic Review of PD‐1/PD‐L1 Inhibitors in Oncology: From Personalized Medicine to Public Health by Chang, Elaine, Pelosof, Lorraine, Lemery, Steven, Gong, Yutao, Goldberg, Kirsten B., Farrell, Ann T., Keegan, Patricia, Veeraraghavan, Janaki, Wei, Guo, Blumenthal, Gideon M., Amiri‐Kordestani, Laleh, Singh, Harpreet, Fashoyin‐Aje, Lola, Gormley, Nicole, Kluetz, Paul G., Pazdur, Richard, Beaver, Julia A., Theoret, Marc R.

“…Background To review and summarize all U.S. Food and Drug Administration (FDA) approvals of programmed death (PD)‐1 and PD‐ligand 1 blocking antibodies…”
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FDA Approval Summary: Lurbinectedin for the Treatment of Metastatic Small Cell Lung Cancer by Singh, Sonia, Jaigirdar, Adnan A, Mulkey, Flora, Cheng, Joyce, Hamed, Salaheldin S, Li, Yangbing, Liu, Jiang, Zhao, Hong, Goheer, Anwar, Helms, Whitney S, Wang, Xing, Agarwal, Rajiv, Pragani, Rajan, Korsah, Kwadwo, Tang, Shenghui, Leighton, John, Rahman, Atiqur, Beaver, Julia A, Pazdur, Richard, Theoret, Marc R, Singh, Harpreet

“…On June 15, 2020, the FDA granted accelerated approval to lurbinectedin for the treatment of adult patients with metastatic small cell lung cancer (SCLC) with…”
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FDA Approval Summary: Ado-Trastuzumab Emtansine for the Adjuvant Treatment of HER2-positive Early Breast Cancer by Wedam, Suparna, Fashoyin-Aje, Lola, Gao, Xin, Bloomquist, Erik, Tang, Shenghui, Sridhara, Rajeshwari, Goldberg, Kirsten B, King-Kallimanis, Bellinda L, Theoret, Marc R, Ibrahim, Amna, Amiri-Kordestani, Laleh, Pazdur, Richard, Beaver, Julia A

“…On May 3, 2019, the FDA granted regular approval to ado-trastuzumab emtansine (KADCYLA), for the adjuvant treatment of patients with HER2-positive early-breast…”
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A monograph of the Xyleborini (Coleoptera, Curculionidae, Scolytinae) of the Indochinese Peninsula (except Malaysia) and China by Smith, Sarah M., Beaver, Roger A., Cognato, Anthony I.

“…The Southeast Asian xyleborine ambrosia beetle fauna is reviewed for the first time. Thirty-four genera and 315 species are reviewed, illustrated, and keyed to…”
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The BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer by Beaver, Julia A, Park, Ben H

“…The combination of the mTOR inhibitor everolimus with the aromatase inhibitor exemestane was evaluated in the randomized Phase III BOLERO-2 trial. Research has…”
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In search of autophagy biomarkers in breast cancer: Receptor status and drug agnostic transcriptional changes during autophagy flux in cell lines by Mascia, Francesca, Mazo, Ilya, Alterovitz, Wei-Lun, Karagiannis, Konstantinos, Wu, Wells W, Shen, Rong-Fong, Beaver, Julia A, Rao, V Ashutosh

“…Autophagy drives drug resistance and drug-induced cancer cell cytotoxicity. Targeting the autophagy process could greatly improve chemotherapy outcomes. The…”
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The Cytoarchitecture of the Tectal-Related Pallium of Squirrelfish, Holocentrus sp by Demski, Leo S, Beaver, Joel A

“…The squirrelfish, which live in visually complex coral reefs, have very large eyes and a special dual-system "day and night vision" retina. They also have…”
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A systematic review of best practices in teaching ophthalmology to medical students by Succar, Tony, MScMed(OphthalSc), PhD, Grigg, John, MBBS, MD, FRANZCO, Beaver, Hilary A., MD, Lee, Andrew G., MD

“…Abstract Ophthalmic medical student education is a cornerstone to improving eye health care globally. We review the current state of the literature, listing…”
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New species and newly recorded species of Anisandrus Ferrari, 1867 ambrosia beetles from Thailand (Coleoptera, Curculionidae, Scolytinae, Xyleborini) by Sittichaya, Wisut, Smith, Sarah M, Beaver, Roger A

“…Five new species, Anisandrus montanus sp. nov. , A. phithakpa sp. nov. , A. tanaosi sp. nov. , A. triton sp. nov. , and A. uniseriatus sp. nov. are described…”
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