Search Results - "Beaurepaire, Renaud de"

A Review of the Potential Mechanisms of Action of Baclofen in Alcohol Use Disorder by de Beaurepaire, Renaud

“…Baclofen, a GABA-B receptor agonist, is a promising treatment for alcohol use disorder (AUD). Its mechanism of action in this condition is unknown. GABA-B…”
Get full text

Baclofen in alcohol use disorder: An analysis of the data provided by the French “Temporary Recommendation for Use” 2014–2017 cohort by de Beaurepaire, Renaud, Rolland, Benjamin

“…Alcohol use disorder (AUD) is a devastating illness for which effective treatments are lacking. Studies over the last two decades have shown that baclofen, a…”
Get full text

Cytokines as mediators of depression: What can we learn from animal studies? by Dunn, Adrian J., Swiergiel, Artur H., Beaurepaire, Renaud de

“…It has recently been postulated that cytokines may cause depressive illness in man. This hypothesis is based on the following observations: 1. Treatment of…”
Get full text

Editorial: Baclofen in the Treatment of Alcohol Use Disorder by de Beaurepaire, Renaud, Heydtmann, Mathis, Agabio, Roberta

Get full text

The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective by de Beaurepaire, Renaud, Sinclair, Julia M A, Heydtmann, Mathis, Addolorato, Giovanni, Aubin, Henri-Jean, Beraha, Esther M, Caputo, Fabio, Chick, Jonathan D, de La Selle, Patrick, Franchitto, Nicolas, Garbutt, James C, Haber, Paul S, Jaury, Philippe, Lingford-Hughes, Anne R, Morley, Kirsten C, Müller, Christian A, Owens, Lynn, Pastor, Adam, Paterson, Louise M, Pélissier, Fanny, Rolland, Benjamin, Stafford, Amanda, Thompson, Andrew, van den Brink, Wim, Leggio, Lorenzo, Agabio, Roberta

“…Alcohol use disorder (AUD) is a brain disorder associated with high rates of mortality and morbidity worldwide. Baclofen, a selective gamma-aminobutyric acid-B…”
Get full text

Dopamine D3 modulation of locomotor activity and sleep in the nucleus accumbens and in lobules 9 and 10 of the cerebellum in the rat by Barik, Samir, de Beaurepaire, Renaud

“…Dopamine D3 receptors are present in the nucleus accumbens and in lobules 9 and 10 of the cerebellum. Their function is not fully understood. In the present…”
Get full text

Binge Eating Disorders in Antipsychotic-Treated Patients With Schizophrenia: Prevalence, Antipsychotic Specificities, and Changes Over Time by de Beaurepaire, Renaud

“…Excessive energy intake likely favors metabolic dysfunction in patients with schizophrenia and may be, in part, the consequence of antipsychotic treatments…”
Get full text

Long term treatment with olanzapine mixed with the food in male rats induces body fat deposition with no increase in body weight and no thermogenic alteration by Minet-Ringuet, Julie, Even, Patrick C., Goubern, Marc, Tomé, Daniel, Beaurepaire, Renaud de

“…Body weight gain is a worrying side effect of many new antipsychotic drugs. The mechanisms by which antipsychotic drugs increase weight in humans are not…”
Get full text

Baclofen in the treatment of alcohol use disorder: tailored doses matter by de Beaurepaire, Renaud, Jaury, Philippe

“…Abstract Aims To address the question of tailored baclofen prescribing in alcohol use disorder (AUD) in relation to dose-dependent efficacy and the potential…”
Get full text

Binge Eating Disorders in Antipsychotic-Treated Patients With Schizophrenia: Prevalence, Antipsychotic Specificities, and Changes Over Time by de Beaurepaire, Renaud

Get full text

Effects of chronic neuroleptic treatments on nutrient selection, body weight, and body composition in the male rat under dietary self-selection by Minet-Ringuet, Julie, Even, Patrick C., Guesdon, Benjamin, Tomé, Daniel, de Beaurepaire, Renaud

“…New antipsychotic drugs often increase weight and produce metabolic disturbances in treated patients. However, the mechanisms by which neuroleptics induce…”
Get full text

A model for antipsychotic-induced obesity in the male rat by MINET-RINGUET, Julie, EVEN, Patrick C, LACROIX, Magali, TOME, Daniel, DE BEAUREPAIRE, Renaud

Get full text

Suppression of alcohol dependence using baclofen: a 2-year observational study of 100 patients by de Beaurepaire, Renaud

“…The purpose of this study was to examine the long-term effects of baclofen in a large cohort of alcohol-dependent patients compliant to baclofen treatment. A…”
Get full text

The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series by de Beaurepaire, Renaud

“…Baclofen, particularly high-dose baclofen, has recently emerged as a treatment of major interest for alcohol-dependence. However, baclofen has many potentially…”
Get full text

Abstinence and 'low-risk' consumption 1 year after the initiation of high-dose baclofen: a retrospective study among 'high-risk' drinkers by Rigal, Laurent, Alexandre-Dubroeucq, Constance, de Beaurepaire, Renaud, Le Jeunne, Claire, Jaury, Philippe

“…The aim of the study was to assess the proportions of 'high-risk' drinkers' abstinent or with 'low-risk' consumption levels 1 year after the initiation of…”
Get full text

Brain imaging and the deconstruction of mind by de Beaurepaire, Renaud

“…Brain imaging techniques today enable the study of functional connectivity between different brain regions, thereby providing insight into an individual's…”
Get full text

Nicotine enhances alcohol intake and dopaminergic responses through β2 and β4 nicotinic acetylcholine receptors by Tolu, Stefania, Marti, Fabio, Morel, Carole, Perrier, Carole, Torquet, Nicolas, Pons, Stephanie, de Beaurepaire, Renaud, Faure, Philippe

“…Alcohol and nicotine are the most widely co-abused drugs. Both modify the activity of dopaminergic (DA) neurons of the Ventral Tegmental Area (VTA) and lead to…”
Get full text

Baclofen for the treatment of alcohol use disorder: the Cagliari Statement by Agabio, Roberta, Sinclair, Julia MA, Addolorato, Giovanni, Aubin, Henri-Jean, Beraha, Esther M, Caputo, Fabio, Chick, Jonathan D, de La Selle, Patrick, Franchitto, Nicolas, Garbutt, James C, Haber, Paul S, Heydtmann, Mathis, Jaury, Philippe, Lingford-Hughes, Anne R, Morley, Kirsten C, Müller, Christian A, Owens, Lynn, Pastor, Adam, Paterson, Louise M, Pélissier, Fanny, Rolland, Benjamin, Stafford, Amanda, Thompson, Andrew, van den Brink, Wim, de Beaurepaire, Renaud, Leggio, Lorenzo

Get full text

Soi et soi/être, de la bactérie au salience network by de Beaurepaire, Renaud

“…La notion de soi reste difficile à définir. L’objectif de cet article est de chercher à mieux comprendre ce qu’est le soi en retraçant son évolution depuis les…”
Get full text

Striatal and Extrastriatal Dopamine Transporter Availability in Schizophrenia and Its Clinical Correlates: A Voxel-Based and High-Resolution PET Study by Artiges, Eric, Leroy, Claire, Dubol, Manon, Prat, Marie, Pepin, Audrey, Mabondo, Audrey, de Beaurepaire, Renaud, Beaufils, Béatrice, Korwin, Jean-Pierre, Galinowski, André, D'Albis, Marc-Antoine, Santiago-Ribeiro, Maria-João, Granger, Bernard, Tzavara, Eleni T, Martinot, Jean-Luc, Trichard, Christian

“…Neuroimaging studies investigating dopamine (DA) function widely support the hypothesis of presynaptic striatal DA hyperactivity in schizophrenia. However,…”
Get full text