Search Results - "Beaumont, Joel E.J."

Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1 by Keulers, Tom G., Libregts, Sten F., Beaumont, Joel E.J., Savelkouls, Kim G., Bussink, Johan, Duimel, Hans, Dubois, Ludwig, Zonneveld, Marijke I., López‐Iglesias, Carmen, Bezstarosti, Karel, Demmers, Jeroen A., Vooijs, Marc, Wauben, Marca, Rouschop, Kasper M.A.

“…Tumour hypoxia is a hallmark of solid tumours and contributes to tumour progression, metastasis development and therapy resistance. In response to hypoxia,…”
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GABARAPL1 is essential in extracellular vesicle cargo loading and metastasis development by Beaumont, Joel E.J., Ju, Jinzhe, Barbeau, Lydie M.O., Demers, Imke, Savelkouls, Kim G., Derks, Kasper, Bouwman, Freek G., Wauben, Marca H.M., Zonneveld, Marijke I., Keulers, Tom G.H., Rouschop, Kasper M.A.

“…•GABARAPL1 is essential for metastasis development.•GABARAPL1 increases cancer cell migration.•Extracellular vesicles increase cancer cell…”
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