Search Results - "Beaumont, Jennifer G."

HLS5, a Novel RBCC (Ring Finger, B Box, Coiled-coil) Family Member Isolated from a Hemopoietic Lineage Switch, Is a Candidate Tumor Suppressor by Lalonde, Jean-Philippe, Lim, Raelene, Ingley, Evan, Tilbrook, Peta A., Thompson, Martin J., McCulloch, Ross, Beaumont, Jennifer G, Wicking, Carol, Eyre, Helen J., Sutherland, Grant R., Howe, Kathy, Solomon, Ellen, Williams, James H., Klinken, S. Peter

“…Hemopoietic cells, apparently committed to one lineage, can be reprogrammed to display the phenotype of another lineage. The J2E erythroleukemic cell line has…”
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Bmf: A Proapoptotic BH3-Only Protein Regulated by Interaction with the Myosin V Actin Motor Complex, Activated by Anoikis by Puthalakath, Hamsa, Villunger, Andreas, O'Reilly, Lorraine A., Beaumont, Jennifer G., Coultas, Leigh, Cheney, Richard E., David C. S. Huang, Strasser, Andreas

“…Bcl-2 family members bearing only the BH3 domain are essential inducers of apoptosis. We identified a BH3-only protein, Bmf, and show that its BH3 domain is…”
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Proapoptotic BH3-Only Proteins Trigger Membrane Integration of Prosurvival Bcl-w and Neutralize Its Activity by Wilson-Annan, Julie, O'Reilly, Lorraine A., Crawford, Simon A., Hausmann, George, Beaumont, Jennifer G., Parma, Loes P., Chen, Lin, Lackmann, Martin, Lithgow, Trevor, Hinds, Mark G., Day, Catherine L., Adams, Jerry M., David C. S. Huang

“…Prosurvival Bcl-2-like proteins, like Bcl-w, are thought to function on organelles such as the mitochondrion and to be targeted to them by their hydrophobic…”
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Hls5 regulated erythroid differentiation by modulating GATA-1 activity by Endersby, Raelene, Majewski, Ian J., Winteringham, Louise, Beaumont, Jennifer G., Samuels, Amy, Scaife, Robin, Lim, Esther, Crossley, Merlin, Klinken, S. Peter, Lalonde, Jean-Philippe

“…Hemopoietic lineage switch (Hls) 5 and 7 were originally isolated as genes up-regulated during an erythroid-to-myeloid lineage switch. We have shown previously…”
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HS1 Interacts with Lyn and Is Critical for Erythropoietin-induced Differentiation of Erythroid Cells by Ingley, Evan, Sarna, Mohinda K., Beaumont, Jennifer G., Tilbrook, Peta A., Tsai, Schickwann, Takemoto, Yoshihiro, Williams, James H., Klinken, S.Peter

“…Erythroid cells terminally differentiate in response to erythropoietin binding its cognate receptor. Previously we have shown that the tyrosine kinase Lyn…”
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HLS7, a hemopoietic lineage switch gene homologous to the leukemia-inducing gene MLF1 by Williams, James H., Daly, Louise N., Ingley, Evan, Beaumont, Jennifer G., Tilbrook, Peta A., Lalonde, Jean-Philippe, Stillitano, Justin P., Klinken, S. Peter

“…Hemopoietic lineage switching occurs when leukemic cells, apparently committed to one lineage, change and display the phenotype of another pathway. cDNA…”
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Thyroid Hormone Receptor-interacting Protein 1 Modulates Cytokine and Nuclear Hormone Signaling in Erythroid Cells by Ingley, E, Chappell, D, Poon, S Y, Sarna, M K, Beaumont, J G, Williams, J H, Stillitano, J P, Tsai, S, Leedman, P J, Tilbrook, P A, Klinken, S P

“…Erythropoietin (Epo) and thyroid hormone (T 3 ) are key molecules in the development of red blood cells. We have shown previously that the tyrosine kinase Lyn…”
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Pro-Apoptotic Apoptosis Protease-Activating Factor 1 (Apaf-1) Has a Cytoplasmic Localization Distinct from Bcl-2 or Bcl- xL by Hausmann, George, O'Reilly, Lorraine A., van Driel, Rosemary, Beaumont, Jennifer G., Strasser, Andreas, Adams, Jerry M., David C. S. Huang

“…How Bcl-2 and its pro-survival relatives prevent activation of the caspases that mediate apoptosis is unknown, but they appear to act through the caspase…”
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Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L) by Hausmann, G, O'Reilly, L A, van Driel, R, Beaumont, J G, Strasser, A, Adams, J M, Huang, D C

“…How Bcl-2 and its pro-survival relatives prevent activation of the caspases that mediate apoptosis is unknown, but they appear to act through the caspase…”
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