Search Results - "Beaudet, Marie‐Josée"
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Tissue‐engineered in vitro modeling of the impact of Schwann cells in amyotrophic lateral sclerosis
Published in Biotechnology and bioengineering (01-07-2022)“…Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease affecting upper and lower motor neurons (MNs). To investigate whether Schwann…”
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Development of an innervated tissue-engineered skin with human sensory neurons and Schwann cells differentiated from iPS cells
Published in Acta biomaterialia (01-12-2018)“…[Display omitted] Cutaneous innervation is increasingly recognized as a major element of skin physiopathology through the neurogenic inflammation driven by…”
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Sensory neurons increase keratinocyte proliferation through CGRP release in a tissue engineered in vitro model of innervation in psoriasis
Published in Acta biomaterialia (01-07-2024)“…Skin denervation has been shown to cause remission of psoriatic lesions in patients, which can reappear if reinnervation occurs. This effect can be induced by…”
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Differentiation of Human Induced Pluripotent Stem Cells into Mature and Myelinating Schwann Cells
Published in Tissue engineering. Part C, Methods (01-04-2023)“…In the peripheral nervous system, Schwann cells (SCs) play a crucial role in axonal growth, metabolic support of neurons, and the production of myelin sheaths…”
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In Vitro Characterization of Motor Neurons and Purkinje Cells Differentiated from Induced Pluripotent Stem Cells Generated from Patients with Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay
Published in Stem cells international (15-04-2023)“…Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an early-onset neurodegenerative disease mainly characterized by spasticity in the lower…”
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High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord
Published in Scientific reports (18-11-2015)“…Extraction of mouse spinal motor neurons from transgenic mouse embryos recapitulating some aspects of neurodegenerative diseases like amyotrophic lateral…”
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Reduced Glioma Growth Following Dexamethasone or Anti-Angiopoietin 2 Treatment
Published in Brain pathology (Zurich, Switzerland) (01-07-2008)“…All patients with glioblastoma, the most aggressive and common form of brain cancer, develop cerebral edema. This complication is routinely treated with…”
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Matrix metalloproteinase 2 attenuates brain tumour growth, while promoting macrophage recruitment and vascular repair
Published in The Journal of pathology (01-06-2011)“…Matrix metalloproteinase 2 (MMP2) is an extracellular protein‐degrading enzyme widely believed to be involved in the invasion of brain tumour cells. However,…”
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Construction of a ganciclovir-sensitive lentiviral vector to assess the influence of angiopoietin-3 and soluble Tie2 on glioma growth
Published in Journal of neuro-oncology (01-08-2010)“…Malignant brain tumors grow by coopting the existing vasculature, a process involving the release of angiopoietin-2 (Angpt2) from endothelial cells and its…”
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The CYP2B2 phenobarbital response unit contains binding sites for hepatocyte nuclear factor 4, PBX-PREP1, the thyroid hormone receptor beta and the liver X receptor
Published in Biochemical journal (01-06-2005)“…A 163 bp enhancer in the CYP2B2 5' flank confers PB (phenobarbital) inducibility and constitutes a PBRU (PB response unit). The PBRU contains several…”
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GABA A/central benzodiazepine receptor and peripheral benzodiazepine receptor ligands as inducers of phenobarbital-inducible CYP2B and CYP3A
Published in Biochemical pharmacology (01-10-2004)“…A sequence critical for phenobarbital (PB) induction, the PB response unit (PBRU), situated upstream of the rat CYP2B1 and CYP2B2 genes, includes two nuclear…”
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GABAA/central benzodiazepine receptor and peripheral benzodiazepine receptor ligands as inducers of phenobarbital-inducible CYP2B and CYP3A
Published in Biochemical pharmacology (01-10-2004)Get full text
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Mutational Analysis of the CYP2B2 Phenobarbital Response Unit and Inhibitory Effect of the Constitutive Androstane Receptor on Phenobarbital Responsiveness
Published in The Journal of biological chemistry (08-12-2000)“…A 163-base pair enhancer in the CYP2B2 5â² flank confers phenobarbital (PB) inducibility and constitutes a PB response unit (PBRU). By transfection of primary…”
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