Search Results - "Beaudenon, Sylvie"

Targeted, High-Depth, Next-Generation Sequencing of Cancer Genes in Formalin-Fixed, Paraffin-Embedded and Fine-Needle Aspiration Tumor Specimens by Hadd, Andrew G, Houghton, Jeff, Choudhary, Ashish, Sah, Sachin, Chen, Liangjing, Marko, Adam C, Sanford, Tiffany, Buddavarapu, Kalyan, Krosting, Julie, Garmire, Lana, Wylie, Dennis, Shinde, Rupali, Beaudenon, Sylvie, Alexander, Erik K, Mambo, Elizabeth, Adai, Alex T, Latham, Gary J

“…Implementation of highly sophisticated technologies, such as next-generation sequencing (NGS), into routine clinical practice requires compatibility with…”
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Herc5, an Interferon-induced HECT E3 Enzyme, Is Required for Conjugation of ISG15 in Human Cells by Dastur, Anahita, Beaudenon, Sylvie, Kelley, Melissa, Krug, Robert M., Huibregtse, Jon M.

“…ISG15 is an interferon (IFN)-α/β-induced ubiquitin-like protein that is conjugated to cellular proteins during innate immune responses to viral and bacterial…”
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The UbcH8 Ubiquitin E2 Enzyme Is also the E2 Enzyme for ISG15, an IFN-α/β-Induced Ubiquitin-Like Protein by Zhao, Chen, Beaudenon, Sylvie L., Kelley, Melissa L., Waddell, M. Brett, Yuan, Weiming, Schulman, Brenda A., Huibregtse, Jon M., Krug, Robert M., Howley, Peter M.

“…Ubiquitin- (Ub) like proteins (Ubls) are conjugated to their targets by an enzymatic cascade involving an E1 activating enzyme, an E2 conjugating enzyme, and…”
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Molecular classification of thyroid lesions by combined testing for miRNA gene expression and somatic gene alterations by Wylie, Dennis, Beaudenon‐Huibregtse, Sylvie, Haynes, Brian C., Giordano, Thomas J., Labourier, Emmanuel

“…Multiple molecular markers contribute to the pathogenesis of thyroid cancer and can provide valuable information to improve disease diagnosis and patient…”
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Molecular Testing for Oncogenic Gene Alterations in Pediatric Thyroid Lesions by Mostoufi-Moab, Sogol, Labourier, Emmanuel, Sullivan, Lisa, LiVolsi, Virginia, Li, Yimei, Xiao, Rui, Beaudenon-Huibregtse, Sylvie, Kazahaya, Ken, Adzick, N Scott, Baloch, Zubair, Bauer, Andrew J

“…Thyroid nodules are less common in pediatric patients (i.e., those ≤18 years) than they are in adults. The Bethesda System for Reporting Thyroid Cytopathology…”
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SARS-CoV-2 viral load is associated with risk of transmission to household and community contacts by Bhavnani, Darlene, James, Emily R, Johnson, Kaitlyn E, Beaudenon-Huibregtse, Sylvie, Chang, Patrick, Rathouz, Paul J, Weldon, Minda, Matouschek, Andreas, Young, Amy E

“…Factors that lead to successful SARS-CoV-2 transmission are still not well described. We investigated the association between a case's viral load and the risk…”
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The Large Subunit of RNA Polymerase II is a Substrate of the Rsp5 Ubiquitin-Protein Ligase by Huibregtse, Jon M., Yang, Joyce C., Beaudenon, Sylvie L.

“…The E3 ubiquitin-protein ligases play an important role in controlling substrate specificity of the ubiquitin proteolysis system. A biochemical approach was…”
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Expression and assay of HECT domain ligases by Beaudenon, Sylvie, Dastur, Anahita, Huibregtse, Jon M

“…HECT domain ubiquitin ligases (HECT E3s), typified by human E6AP and yeast Rsp5p, are unique among the several classes of known ubiquitin ligases in that they…”
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Molecular testing for oncogenic gene mutations in thyroid lesions: a case-control validation study in 413 postsurgical specimens by Giordano, Thomas J., MD, PhD, Beaudenon-Huibregtse, Sylvie, PhD, Shinde, Rupali, MS, Langfield, Laura, BA, Vinco, Michelle, MS, Laosinchai-Wolf, Walairat, PhD, Labourier, Emmanuel, PhD

“…Summary Molecular testing for oncogenic gene alterations provides clinically actionable information essential for the optimal management of follicular cell…”
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Rsp5 Ubiquitin-Protein Ligase Mediates DNA Damage-Induced Degradation of the Large Subunit of RNA Polymerase II in Saccharomyces cerevisiae by Beaudenon, Sylvie L., Huacani, Maria R., Wang, Guangli, McDonnell, Donald P., Huibregtse, Jon M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human Papillomavirus Type 16 E6 Induces Self-Ubiquitination of the E6AP Ubiquitin-Protein Ligase by Kao, W H, Beaudenon, S L, Talis, A L, Huibregtse, J M, Howley, P M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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HPV E6, E6AP and cervical cancer by Beaudenon, Sylvie, Huibregtse, Jon M

“…Every year, approximately 470,000 new cases of cervical cancer are diagnosed and approximately 230,000 women worldwide die of the disease, with the majority…”
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Mechanism of HPV E6 proteins in cellular transformation by Huibregtse, Jon M., Beaudenon, Sylvie L.

“…The E6 protein is a major transforming protein of many types of papillomaviruses. Mechanistically, the best characterized E6 proteins are those of the…”
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Bowenoid papulosis of the male and female genitalia: risk of cervical neoplasia by Obalek, S, Jablonska, S, Beaudenon, S, Walczak, L, Orth, G

“…Sixteen patients with bowenoid papulosis (eleven male patients with bowenoid papulosis of the penis and five female patients with bowenoid papulosis of the…”
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Evaluation of an integrated clinical workflow for targeted next-generation sequencing of low-quality tumor DNA using a 51-gene enrichment panel by Choudhary, Ashish, Mambo, Elizabeth, Sanford, Tiffany, Boedigheimer, Michael, Twomey, Brian, Califano, Joseph, Hadd, Andrew, Oliner, Kelly S, Beaudenon, Sylvie, Latham, Gary J, Adai, Alex T

“…Improvements in both performance and cost for next-generation sequencing (NGS) have spurred its rapid adoption for clinical applications. We designed and…”
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Structure of an E6AP-UbcH7 Complex: Insights into Ubiquitination by the E2- E3 Enzyme Cascade by Huang, Lan, Kinnucan, Elspeth, Wang, Guangli, Beaudenon, Sylvie, Howley, Peter M., Huibregtse, Jon M., Pavletich, Nikola P.

“…The E6AP ubiquitin-protein ligase (E3) mediates the human papillomavirus-induced degradation of the p53 tumor suppressor in cervical cancer and is mutated in…”
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Molecular Testing for miRNA, mRNA, and DNA on Fine-Needle Aspiration Improves the Preoperative Diagnosis of Thyroid Nodules With Indeterminate Cytology by Labourier, Emmanuel, Shifrin, Alexander, Busseniers, Anne E, Lupo, Mark A, Manganelli, Monique L, Andruss, Bernard, Wylie, Dennis, Beaudenon-Huibregtse, Sylvie

“…Context: Molecular testing for oncogenic mutations or gene expression in fine-needle aspirations (FNAs) from thyroid nodules with indeterminate cytology…”
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Indoor Allergen Exposure and Its Influence on Upper Respiratory Infections and Pulmonary Outcomes among Children with Asthma by Bhavnani, Darlene, Beaudenon-Huibregtse, Sylvie, Davis, Meghan, McCormack, Meredith, Keet, Corinne, Balcer-Whaley, Susan, Newman, Michelle, Matsui, Elizabeth

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A Family of Proteins Structurally and Functionally Related to the E6-AP Ubiquitin-Protein Ligase by Huibregtse, Jon M., Scheffner, Martin, Beaudenon, Sylvie, Howley, Peter M.

“…E6-AP is a 100-kDa cellular protein that interacts with the E6 protein of the cancer-associated human papillomavirus types 16 and 18. The E6/E6-AP complex…”
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Centralized molecular testing for oncogenic gene mutations complements the local cytopathologic diagnosis of thyroid nodules by Beaudenon-Huibregtse, Sylvie, Alexander, Erik K, Guttler, Richard B, Hershman, Jerome M, Babu, Varsha, Blevins, Thomas C, Moore, Paul, Andruss, Bernard, Labourier, Emmanuel

“…Molecular testing for oncogenic gene mutations and chromosomal rearrangements plays a growing role in the optimal management of thyroid nodules, yet lacks…”
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