Search Results - "Beattie, John H"

Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ by Trayhurn, Paul, Beattie, John H.

“…The traditional role attributed to white adipose tissue is energy storage, fatty acids being released when fuel is required. The metabolic role of white fat…”
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Marginal dietary zinc deficiency in vivo induces vascular smooth muscle cell apoptosis in large arteries by Allen-Redpath, Keith, Ou, Ou, Beattie, John H, Kwun, In-Sook, Feldmann, Jorg, Nixon, Graeme F

“…Dietary zinc deficiency has been associated with the development of atherosclerosis although the effects on vascular smooth muscle cells (VSMCs), important in…”
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Long-term zinc deprivation accelerates rat vascular smooth muscle cell proliferation involving the down-regulation of JNK1/2 expression in MAPK signaling by Alcantara, Ethel H, Shin, Mee Young, Feldmann, Jörg, Nixon, Graeme F, Beattie, John H, Kwun, In Sook

“…Abstract Background The accelerated proliferation of vascular smooth muscle cells (VSMCs) is a contributor for atherosclerosis by thickening the vascular wall…”
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Preliminary evidence of immune function modulation by thyroid hormones in healthy men and women aged 55–70 years by Hodkinson, Clare F, Simpson, Ellen E A, Beattie, John H, O'Connor, Jacqueline M, Campbell, David J, Strain, J J, Wallace, Julie M W

“…A reciprocal relationship between the endocrine and immune system has been demonstrated under pathophysiological conditions. However, few studies have assessed…”
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Suboptimal dietary zinc intake promotes vascular inflammation and atherogenesis in a mouse model of atherosclerosis by Beattie, John H., Gordon, Margaret-Jane, Duthie, Susan J., McNeil, Chris J., Horgan, Graham W., Nixon, Graeme F., Feldmann, Jörg, Kwun, In-Sook

“…Scope Cardiovascular health is strongly influenced by diet. Zinc has antioxidant and anti‐inflammatory properties but its long‐term influence on vascular…”
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Microanalytical isotope ratio measurements and elemental mapping using laser ablation ICP-MS for tissue thin sections: zinc tracer studies in rats by Urgast, Dagmar S., Ou, Ou, Gordon, Margaret-Jane, Raab, Andrea, Nixon, Graeme F., Kwun, In-Sook, Beattie, John H., Feldmann, Jörg

“…The kinetics of zinc absorption, metabolism and excretion is extensively studied by nutritionists. Stable isotopes of zinc can be used to identify body zinc…”
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Ginger phytochemicals mitigate the obesogenic effects of a high-fat diet in mice: A proteomic and biomarker network analysis by Beattie, John H., Nicol, Fergus, Gordon, Margaret-Jane, Reid, Martin D., Cantlay, Louise, Horgan, Graham W., Kwun, In-Sook, Ahn, Ji-Yun, Ha, Tae-Youl

“…Scope: Natural dietary anti‐obesogenic phytochemicals may help combat the rising global incidence of obesity. We aimed to identify key hepatic pathways…”
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Is zinc deficiency a risk factor for atherosclerosis? by Beattie, John H., Kwun, In-Sook

“…The development of atherosclerosis is influenced by genetic, lifestyle and nutritional risk factors. Zn and metallothionein deficiency can enhance…”
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Plasma zinc's alter ego is a low‐molecular‐weight humoral factor by Ou, Ou, Allen‐Redpath, Keith, Urgast, Dagmar, Gordon, Margaret‐Jane, Campbell, Gill, Feldmann, Jörg, Nixon, Graeme F., Mayer, Claus‐Dieter, Kwun, In‐Sook, Beattie, John H.

“…Mild dietary zinc deprivation in humans and rodents has little effect on blood plasma zinc levels, and yet cellular consequences of zinc depletion can be…”
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Multi-elemental bio-imaging of rat tissue from a study investigating the bioavailability of bismuth from shotgun pellets by Urgast, Dagmar S., Ellingsen, Dag G., Berlinger, Balázs, Eilertsen, Einar, Friisk, Grete, Skaug, Vidar, Thomassen, Yngvar, Beattie, John H., Kwun, In-Sook, Feldmann, Jörg

“…In recent years, bismuth has been promoted as a “green element” and is used as a substitute for the toxic lead in ammunition and other applications. However,…”
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Zinc transporters and dysregulated channels in cancers by Pan, Zui, Choi, Sangyong, Ouadid-Ahidouch, Halima, Yang, Jin-Ming, Beattie, John H, Korichneva, Irina

“…As a nutritionally essential metal ion, zinc (Zn) not only constitutes a structural element for more than 3000 proteins but also plays important regulatory…”
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Nutritional B vitamin deficiency disrupts lipid metabolism causing accumulation of proatherogenic lipoproteins in the aorta adventitia of ApoE null mice by McNeil, Christopher J., Beattie, John H., Gordon, Margaret-Jane, Pirie, Lynn P., Duthie, Susan J.

“…ScopeCardiovascular disease is the major cause of death in the world. Low dietary folate, elevated homocysteine, and high circulating cholesterol are risk…”
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Zinc Status Alters Alzheimer's Disease Progression through NLRP3-Dependent Inflammation by Rivers-Auty, Jack, Tapia, Victor S, White, Claire S, Daniels, Michael J D, Drinkall, Samuel, Kennedy, Paul T, Spence, Harry G, Yu, Shi, Green, Jack P, Hoyle, Christopher, Cook, James, Bradley, Amy, Mather, Alison E, Peters, Ruth, Tzeng, Te-Chen, Gordon, Margaret J, Beattie, John H, Brough, David, Lawrence, Catherine B

“…Alzheimer's disease is a devastating neurodegenerative disease with a dramatically increasing prevalence and no disease-modifying treatment. Inflammatory…”
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Marginal zinc deficiency in rats decreases leptin expression independently of food intake and corticotrophin-releasing hormone in relation to food intake by Kwun, In-Sook, Cho, Young-Eun, Lomeda, Ria-Ann R., Kwon, Soon-Tae, Kim, Yangha, Beattie, John H.

“…Zn deficiency reduces food intake and growth rate in rodents. To determine the relationship between Zn deficiency and the regulation of food intake, we…”
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Zinc deficiency suppresses matrix mineralization and retards osteogenesis transiently with catch-up possibly through Runx 2 modulation by Kwun, In-Sook, Cho, Young-Eun, Lomeda, Ria-Ann R, Shin, Hong-In, Choi, Je-Yong, Kang, Young-Hee, Beattie, John H

“…Abstract A characteristic sign of zinc deficiency is retarded skeletal growth, but the role of zinc in osteoblasts is not well understood. Two major events for…”
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Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia–reperfusion injury through depletion of glutathione by Skene, Karen, Walsh, Sarah K., Okafor, Oronne, Godsman, Nadine, Barrows, Charlotte, Meier, Philip, Gordon, Margaret J., Beattie, John H., Wainwright, Cherry L.

“…Zn plays an important role in maintaining the anti-oxidant status within the heart and helps to counter the acute redox stress that occurs during myocardial…”
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Imaging of trace elements in tissues: with a focus on laser ablation inductively coupled plasma mass spectrometry by Urgast, Dagmar S, Beattie, John H, Feldmann, Jörg

“…PURPOSE OF REVIEWElemental imaging techniques are capable of showing the spatial distribution of elements in a sample. Their application in biomedical sciences…”
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Metallothionein gene expression and secretion in white adipose tissue by Trayhurn, P, Duncan, J S, Wood, A M, Beattie, J H

“…White adipose tissue (WAT) has been examined to determine whether the gene encoding metallothionein (MT), a low-molecular-weight stress response protein, is…”
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On-line solid-phase extraction–capillary electrophoresis for enhanced detection sensitivity and selectivity: application to the analysis of metallothionein isoforms in sheep fetal liver by Knudsen, Carsten B, Beattie, John H

“…A simple and rapid capillary electrophoresis (CE) method for analysis of metallothionein (MT) isoforms is described. A modified two-step solvent extraction…”
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Zinc deprivation inhibits extracellular matrix calcification through decreased synthesis of matrix proteins in osteoblasts by Alcantara, Ethel H., Lomeda, Ria-Ann R., Feldmann, Joerg, Nixon, Graeme F., Beattie, John H., Kwun, In-Sook

“…Scope: Zinc is implicated as an activator for bone formation, however, its influence on bone calcification has not been reported. This study examined how zinc…”
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