Search Results - "Beattie, John"
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Zinc transporters and dysregulated channels in cancers
Published in Frontiers in bioscience (01-01-2017)“…As a nutritionally essential metal ion, zinc (Zn) not only constitutes a structural element for more than 3000 proteins but also plays important regulatory…”
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2
Zinc Status Alters Alzheimer's Disease Progression through NLRP3-Dependent Inflammation
Published in The Journal of neuroscience (31-03-2021)“…Alzheimer's disease is a devastating neurodegenerative disease with a dramatically increasing prevalence and no disease-modifying treatment. Inflammatory…”
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3
Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ
Published in Proceedings of the Nutrition Society (01-08-2001)“…The traditional role attributed to white adipose tissue is energy storage, fatty acids being released when fuel is required. The metabolic role of white fat…”
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4
Zinc deficiency suppresses matrix mineralization and retards osteogenesis transiently with catch-up possibly through Runx 2 modulation
Published in Bone (New York, N.Y.) (01-03-2010)“…Abstract A characteristic sign of zinc deficiency is retarded skeletal growth, but the role of zinc in osteoblasts is not well understood. Two major events for…”
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5
Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia–reperfusion injury through depletion of glutathione
Published in British journal of nutrition (01-05-2019)“…Zn plays an important role in maintaining the anti-oxidant status within the heart and helps to counter the acute redox stress that occurs during myocardial…”
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6
Marginal dietary zinc deficiency in vivo induces vascular smooth muscle cell apoptosis in large arteries
Published in Cardiovascular research (01-08-2013)“…Dietary zinc deficiency has been associated with the development of atherosclerosis although the effects on vascular smooth muscle cells (VSMCs), important in…”
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Long-term zinc deprivation accelerates rat vascular smooth muscle cell proliferation involving the down-regulation of JNK1/2 expression in MAPK signaling
Published in Atherosclerosis (01-05-2013)“…Abstract Background The accelerated proliferation of vascular smooth muscle cells (VSMCs) is a contributor for atherosclerosis by thickening the vascular wall…”
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8
Imaging of trace elements in tissues: with a focus on laser ablation inductively coupled plasma mass spectrometry
Published in Current opinion in clinical nutrition and metabolic care (01-09-2014)“…PURPOSE OF REVIEWElemental imaging techniques are capable of showing the spatial distribution of elements in a sample. Their application in biomedical sciences…”
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Performance evaluation of the bio-rad BioPlex 2200 multiplex system in the detection of measles, mumps, rubella, and varicella-zoster antibodies
Published in Journal of clinical virology plus (01-02-2023)“…•Measles, mumps, rubella, and varicella-zoster (MMRV) immunity testing is important in occupational screening of healthcare workers and at-risk…”
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10
Scintigraphy in laryngopharyngeal and gastroesophageal reflux disease:A definitive diagnostic test?
Published in World journal of gastroenterology : WJG (28-03-2015)“…AIM: To investigate the utility of scintigraphic studies in predicting response to laparoscopic fundoplication(LF) for chronic laryngopharyngeal reflux…”
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11
Suboptimal dietary zinc intake promotes vascular inflammation and atherogenesis in a mouse model of atherosclerosis
Published in Molecular nutrition & food research (01-07-2012)“…Scope Cardiovascular health is strongly influenced by diet. Zinc has antioxidant and anti‐inflammatory properties but its long‐term influence on vascular…”
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12
Preliminary evidence of immune function modulation by thyroid hormones in healthy men and women aged 55–70 years
Published in Journal of endocrinology (01-07-2009)“…A reciprocal relationship between the endocrine and immune system has been demonstrated under pathophysiological conditions. However, few studies have assessed…”
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13
Microanalytical isotope ratio measurements and elemental mapping using laser ablation ICP-MS for tissue thin sections: zinc tracer studies in rats
Published in Analytical and bioanalytical chemistry (01-01-2012)“…The kinetics of zinc absorption, metabolism and excretion is extensively studied by nutritionists. Stable isotopes of zinc can be used to identify body zinc…”
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14
Ginger phytochemicals mitigate the obesogenic effects of a high-fat diet in mice: A proteomic and biomarker network analysis
Published in Molecular nutrition & food research (01-09-2011)“…Scope: Natural dietary anti‐obesogenic phytochemicals may help combat the rising global incidence of obesity. We aimed to identify key hepatic pathways…”
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15
Plasma zinc's alter ego is a low‐molecular‐weight humoral factor
Published in The FASEB journal (01-09-2013)“…Mild dietary zinc deprivation in humans and rodents has little effect on blood plasma zinc levels, and yet cellular consequences of zinc depletion can be…”
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16
Is zinc deficiency a risk factor for atherosclerosis?
Published in British journal of nutrition (01-02-2004)“…The development of atherosclerosis is influenced by genetic, lifestyle and nutritional risk factors. Zn and metallothionein deficiency can enhance…”
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17
Esophageal Clearance in Laryngopharyngeal Reflux Disease: Correlation of Reflux Scintigraphy and 24-hour Impedance/pH in a Cohort of Refractory Symptomatic Patients
Published in Molecular imaging and radionuclide therapy (01-02-2020)“…The role of gastroesophageal reflux disease (GERD) in the aetiology of laryngopharyngeal reflux (LPR) is poorly understood and remains a controversial issue…”
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18
Multi-elemental bio-imaging of rat tissue from a study investigating the bioavailability of bismuth from shotgun pellets
Published in Analytical and bioanalytical chemistry (01-07-2012)“…In recent years, bismuth has been promoted as a “green element” and is used as a substitute for the toxic lead in ammunition and other applications. However,…”
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19
Zinc deprivation inhibits extracellular matrix calcification through decreased synthesis of matrix proteins in osteoblasts
Published in Molecular nutrition & food research (01-10-2011)“…Scope: Zinc is implicated as an activator for bone formation, however, its influence on bone calcification has not been reported. This study examined how zinc…”
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A practical approach for the validation and clinical implementation of a high-sensitivity cardiac troponin I assay across a North American city
Published in Practical laboratory medicine (01-04-2015)“…Despite several publications on the analytical performance of high-sensitivity cardiac troponin (hs-cTn) assays, there has been little information on how…”
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