Search Results - "Beattie, Bryan K."

Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II by Krogan, Nevan J., Kim, Minkyu, Tong, Amy, Golshani, Ashkan, Cagney, Gerard, Canadien, Veronica, Richards, Dawn P., Beattie, Bryan K., Emili, Andrew, Boone, Charles, Shilatifard, Ali, Buratowski, Stephen, Greenblatt, Jack

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RPAP1, a Novel Human RNA Polymerase II-Associated Protein Affinity Purified with Recombinant Wild-Type and Mutated Polymerase Subunits by Jeronimo, Célia, Langelier, Marie-France, Zeghouf, Mahel, Cojocaru, Marilena, Bergeron, Dominique, Baali, Dania, Forget, Diane, Mnaimneh, Sanie, Davierwala, Armaity P., Pootoolal, Jeff, Chandy, Mark, Canadien, Veronica, Beattie, Bryan K., Richards, Dawn P., Workman, Jerry L., Hughes, Timothy R., Greenblatt, Jack, Coulombe, Benoit

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Regulation of Erythropoietin-induced STAT Serine Phosphorylation by Distinct Mitogen-activated Protein Kinases by Haq, Rizwan, Halupa, Adrienne, Beattie, Bryan K., Mason, Jacqueline M., Zanke, Brent W., Barber, Dwayne L.

“…The STAT proteins are a family of latent transcription factors that are activated by a wide variety of cytokines. Upon receptor engagement, STATs become…”
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The SH2B1 Adaptor Protein Associates with a Proximal Region of the Erythropoietin Receptor by Javadi, Mojib, Hofstätter, Edda, Stickle, Natalie, Beattie, Bryan K., Jaster, Robert, Carter-Su, Christin, Barber, Dwayne L.

“…Background: Animal modeling experiments suggest additional SH2 effectors bind to the erythropoietin receptor (EPO-R) Tyr(P)-343. Results: SH2B1 constitutively…”
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A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation by Barber, Dwayne L., Beattie, Bryan K., Mason, Jacqueline M., Nguyen, Melody H.-H., Yoakim, Monique, Neel, Benjamin G., D'Andrea, Alan D., Frank, David A.

“…Erythropoietin (EPO) specifically activates the Janus kinase JAK2 and the transcription factor signal transducer and activator of transcription-5 (STAT5). All…”
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Fusion of the ets Transcription Factor TEL to Jak2 Results in Constitutive Jak-Stat Signaling by Ho, Jen M.-Y., Beattie, Bryan K., Squire, Jeremy A., Frank, David A., Barber, Dwayne L.

“…To study constitutive Janus kinase signaling, chimeric proteins were generated between the pointed domain of the etstranscription factor TEL and the cytosolic…”
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TEL-JAK2 constitutively activates the extracellular signal–regulated kinase (ERK), stress-activated protein/Jun kinase (SAPK/JNK), and p38 signaling pathways by Ho, Jenny M.-Y., Nguyen, Melody H.-H., Dierov, Jamil K., Badger, Karla M., Beattie, Bryan K., Tartaro, Piero, Haq, Rizwan, Zanke, Brent W., Carroll, Martin P., Barber, Dwayne L.

“…The ets transcription factor, TEL, undergoes chromosomal rearrangements with the tyrosine kinase JAK2. TEL-JAK2 is constitutively active, confers cell line…”
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Identification of the Erythropoietin Receptor Domain Required for Calcium Channel Activation by Miller, B A, Barber, D L, Bell, L L, Beattie, B K, Zhang, M Y, Neel, B G, Yoakim, M, Rothblum, L I, Cheung, J Y

“…Erythropoietin (Epo) activates a voltage-independent Ca 2+ channel that is dependent on tyrosine phosphorylation. To identify the domain(s) of the Epo receptor…”
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The SH2 Inositol 5-Phosphatase Ship1 Is Recruited in an SH2-dependent Manner to the Erythropoietin Receptor by Mason, Jacqueline M., Beattie, Bryan K., Liu, Qiurong, Dumont, Daniel J., Barber, Dwayne L.

“…Ship1 (SH2 inositol 5-phosphatase 1) has been shown to be a target of tyrosine phosphorylation downstream of cytokine and immunoregulatory receptors. In…”
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Investigation into the Catalytic Role for the Tryptophan Residues within Domain III of Pseudomonas aeruginosa Exotoxin A by Beattie, Bryan K, Prentice, Gerry A, Merrill, A. Rod

“…The role of the tryptophan residues in the substrate-binding and catalytic mechanism of an enzymatically active C-terminal fragment of Pseudomonas aeruginosa…”
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In Vitro Enzyme Activation and Folded Stability of Pseudomonas aeruginosa Exotoxin A and Its C-Terminal Peptide by Beattie, Bryan K, Merrill, A. Rod

“…Pseudomonas aeruginosa exotoxin A (ETA) and its C-terminal, enzymatically active fragment (PE40, 375 residues) were studied by high-performance size-exclusion…”
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A minimal cytoplasmic subdomain of the erythropoietin receptor mediates p70 S6 kinase phosphorylation by Zhang, Min-Ying, Barber, Dwayne L, Alessi, Dario R, Bell, Laurie L, Stine, Carol, Nguyen, Melody H.-H, Beattie, Bryan K, Cheung, Joseph Y, Miller, Barbara A

“…Erythropoietin (EPO) is a lineage-restricted growth factor that is required for erythroid proliferation and differentiation. EPO stimulates the phosphorylation…”
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The SH2-B Adaptor Protein Negatively Regulates EPO-Dependent Signalling Via Interaction with Erythropoietin Receptor Ptyr-343 by Javed, Mojib Javadi, Tschirch, Edda, Beattie, Bryan K, Stickle, Natalie, Huang, Kai, Jaster, Robert, Carter-Su, Christin, Barber, Dwayne

“…Erythropoiesis is a developmentally important process, whereby multipotent hematopoietic stem cells differentiate into mature erythrocytes. Erythropoietin…”
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Fusion of the ets Transcription Factor TEL to Jak2 Results in Constitutive Jak-Stat Signaling by Ho, Jen M.-Y., Beattie, Bryan K., Squire, Jeremy A., Frank, David A., Barber, Dwayne L.

“…To study constitutive Janus kinase signaling, chimeric proteins were generated between the pointed domain of the etstranscription factor TEL and the cytosolic…”
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TEL-JAK2 Mediates Constitutive Activation of the Phosphatidylinositol 3′-Kinase/Protein Kinase B Signaling Pathway by Nguyen, Melody H.-H., Ho, Jenny M.-Y., Beattie, Bryan K., Barber, Dwayne L.

“…A subset of chromosomal translocations that participate in leukemia involve activated tyrosine kinases. Theets transcription factor, TEL, undergoes…”
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Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase Cγ by Halupa, Adrienne, Chohan, Manprit, Stickle, Natalie H., Beattie, Bryan K., Miller, Barbara A., Barber, Dwayne L.

“…Red blood cell development is primarily controlled by erythropoietin (EPO). Several studies have revealed the importance of EPO-R Y343 and Y479 for erythroid…”
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Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase Cgamma by Halupa, Adrienne, Chohan, Manprit, Stickle, Natalie H, Beattie, Bryan K, Miller, Barbara A, Barber, Dwayne L

“…Red blood cell development is primarily controlled by erythropoietin (EPO). Several studies have revealed the importance of EPO-R Y343 and Y479 for erythroid…”
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Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase C[gamma] by Halupa, Adrienne, Chohan, Manprit, Stickle, Natalie H, Beattie, Bryan K, Miller, Barbara A, Barber, Dwayne L

“…Red blood cell development is primarily controlled by erythropoietin (EPO). Several studies have revealed the importance of EPO-R Y343 and Y479 for erythroid…”
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TEL-JAK2 Mediates Constitutive Activation of the Phosphatidylinositol 3′-Kinase/Protein Kinase B Signaling Pathway by Melody H.-H. Nguyen, Jenny M.-Y. Ho, Bryan K. Beattie, Dwayne L. Barber

“…A subset of chromosomal translocations that participate in leukemia involve activated tyrosine kinases. The ets transcription factor, TEL, undergoes…”
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RPAP1, a Novel Human RNA Polymerase II-Associated Protein Affinity Purified with Recombinant Wild-Type and Mutated Polymerase Subunits by Jeronimo, Celia, Langelier, Marie-France, Zeghouf, Mahel, Cojocaru, Marilena, Bergeron, Dominique, Baali, Dania, get, Diane, Mnaimneh, Sanie, Davierwala, Armaity P, Pootoolal, Jeff, Chandy, Mark, Canadien, Veronica, Beattie, Bryan K, Richards, Dawn P, Workman, Jerry L, Hughes, Timothy R, Greenblatt, Jack, Coulombe, Benoit

“…We have programmed human cells to express physiological levels of recombinant RNA polymerase II (RNAPII) subunits carrying tandem affinity purification (TAP)…”
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