Search Results - "Beatrice Aricò"
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Outer Membrane Vesicles (OMV)-based and Proteomics-driven Antigen Selection Identifies Novel Factors Contributing to Bordetella pertussis Adhesion to Epithelial Cells
Published in Molecular & cellular proteomics (01-02-2018)“…Despite high vaccination coverage world-wide, whooping cough, a highly contagious disease caused by Bordetella pertussis, is recently increasing in occurrence…”
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Physiopathological roles of spontaneously released outer membrane vesicles of Bordetella pertussis
Published in Future microbiology (01-11-2017)“…Bordetella pertussis has been shown to release outer membrane vesicles (OMV) both in vitro and in vivo but little is known about their biological role during…”
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Neisserial Heparin Binding Antigen (NHBA) Contributes to the Adhesion of Neisseria meningitidis to Human Epithelial Cells
Published in PloS one (25-10-2016)“…Neisserial Heparin Binding Antigen (NHBA) is a surface-exposed lipoprotein ubiquitously expressed by Neisseria meningitidis strains and an antigen of the…”
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Rational design of a meningococcal antigen inducing broad protective immunity
Published in Science translational medicine (13-07-2011)“…The sequence variability of protective antigens is a major challenge to the development of vaccines. For Neisseria meningitidis, the bacterial pathogen that…”
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Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870
Published in The Journal of experimental medicine (17-03-2003)“…Sepsis and meningitis caused by serogroup B meningococcus are devastating diseases of infants and young adults, which cannot yet be prevented by vaccination…”
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LytM proteins play a crucial role in cell separation, outer membrane composition, and pathogenesis in nontypeable Haemophilus influenzae
Published in mBio (01-05-2015)“…LytM proteins belong to a family of bacterial metalloproteases. In Gram-negative bacteria, LytM factors are mainly reported to have a direct effect on cell…”
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Neisseria meningitidis subverts the polarized organization and intracellular trafficking of host cells to cross the epithelial barrier
Published in Cellular microbiology (01-09-2015)“…Summary Translocation of the nasopharyngeal barrier by Neisseria meningitidis occurs via an intracellular microtubule‐dependent pathway and represents a…”
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The C2 fragment from Neisseria meningitidis antigen NHBA increases endothelial permeability by destabilizing adherens junctions
Published in Cellular microbiology (01-06-2014)“…Summary Neisseria meningitidis is a human pathogen that can cause fatal sepsis and meningitis once it reaches the blood stream and the nervous system. Here we…”
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The membrane expression of Neisseria meningitidis adhesin A (NadA) increases the proimmune effects of MenB OMVs on human macrophages, compared with NadA– OMVs, without further stimulating their proinflammatory activity on circulating monocytes
Published in Journal of leukocyte biology (01-07-2009)“…Anti‐Meningococcus B vaccine candidate stimulates macrophages. Hypervirulent MenB causing fatal human infections frequently display the oligomeric‐coiled coil…”
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Role of ARF6, Rab11 and external Hsp90 in the trafficking and recycling of recombinant-soluble Neisseria meningitidis adhesin A (rNadA) in human epithelial cells
Published in PloS one (27-10-2014)“…Neisseria meningitidis adhesin A (NadA) is a meningococcus surface protein thought to assist in the adhesion of the bacterium to host cells. We have previously…”
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NadA, a novel vaccine candidate of Neisseria meningitidis
Published in The Journal of experimental medicine (03-06-2002)“…Neisseria meningitidis is a human pathogen, which, in spite of antibiotic therapy, is still a major cause of mortality due to sepsis and meningitis. Here we…”
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Neisseria meningitidis NadA is a new invasin which promotes bacterial adhesion to and penetration into human epithelial cells
Published in Molecular microbiology (01-02-2005)“…Summary Neisseria meningitidis is a human pathogen, which is a major cause of sepsis and meningitis. The bacterium colonizes the upper respiratory tract…”
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Neisseria meningitidis NhhA is a multifunctional trimeric autotransporter adhesin
Published in Molecular microbiology (01-08-2006)“…Summary NhhA, Neisseriahia/hsf homologue, or GNA0992, is an oligomeric outer membrane protein of Neisseria meningitidis, recently included in the family of…”
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Region Comprising Amino Acids 100 to 255 of Neisseria meningitidis Lipoprotein GNA 1870 Elicits Bactericidal Antibodies
Published in Infection and Immunity (01-02-2005)“…GNA 1870 is a novel surface-exposed lipoprotein, identified by genome analysis of Neisseria meningitidis strain MC58, which induces bactericidal antibodies…”
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Development of a serological assay to predict antibody bactericidal activity against non-typeable Haemophilus influenzae
Published in BMC microbiology (18-04-2015)“…Non-typeable Haemophilus influenzae (NTHi) is a Gram negative microorganism residing in the human nasopharyngeal mucosa and occasionally causing infections of…”
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A Naturally Occurring Single-Residue Mutation in the Translocator Domain of Neisseria meningitidis NhhA Affects Trimerization, Surface Localization, and Adhesive Capabilities
Published in Infection and Immunity (01-11-2011)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mapping of the Neisseria meningitidis NadA Cell-Binding Site: Relevance of Predicted α-Helices in the NH2-Terminal and Dimeric Coiled-Coil Regions
Published in Journal of Bacteriology (01-01-2011)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)‐mediated adhesion and invasion
Published in Cellular microbiology (01-03-2012)“…Summary NadA (N eisseria meningitidisadhesin A), a meningococcal surface protein, mediates adhesion to and invasion of human cells, an activity in which host…”
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IFN-gamma and R-848 dependent activation of human monocyte-derived dendritic cells by Neisseria meningitidis adhesin A
Published in Journal of Immunology (15-09-2007)“…A soluble recombinant form of Neisseria meningitidis adhesin A (NadADelta351-405), proposed as a constituent of anti-meningococcal B vaccines, is here shown to…”
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Molecular Engineering of Ghfp, the Gonococcal Orthologue of Neisseria meningitidis Factor H Binding Protein
Published in Clinical and vaccine immunology (01-07-2015)“…Knowledge of the sequences and structures of proteins produced by microbial pathogens is continuously increasing. Besides offering the possibility of…”
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