Search Results - "Beasley, Heather K."
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A Universal Approach to Analyzing Transmission Electron Microscopy with ImageJ
Published in Cells (Basel, Switzerland) (24-08-2021)“…Transmission electron microscopy (TEM) is widely used as an imaging modality to provide high-resolution details of subcellular components within cells and…”
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Considerations for developing mitochondrial transplantation techniques for individualized medicine
Published in BioTechniques (01-04-2024)“…Mitochondrial transplantation has been used to treat various diseases associated with mitochondrial dysfunction. Here, we highlight the considerations in…”
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Is space the final frontier for mitochondrial study?
Published in BioTechniques (01-02-2024)“…This perspective considers several avenues for future research on mitochondrial dynamics, stress, and DNA in outer space…”
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Reciprocal expression of Annexin A6 and RasGRF2 discriminates rapidly growing from invasive triple negative breast cancer subsets
Published in PloS one (16-04-2020)“…Actively growing tumors are often histologically associated with Ki67 positivity, while the detection of invasiveness relies on non-quantitative pathologic…”
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Combining Metabolomics and Experimental Evolution Reveals Key Mechanisms Underlying Longevity Differences in Laboratory Evolved Drosophila melanogaster Populations
Published in International journal of molecular sciences (19-01-2022)“…Experimental evolution with has been used extensively for decades to study aging and longevity. In recent years, the addition of DNA and RNA sequencing to this…”
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TMEM135 is a Novel Regulator of Mitochondrial Dynamics and Physiology with Implications for Human Health Conditions
Published in Cells (Basel, Switzerland) (11-07-2021)“…Transmembrane proteins (TMEMs) are integral proteins that span biological membranes. TMEMs function as cellular membrane gates by modifying their conformation…”
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Protocols for Generating Surfaces and Measuring 3D Organelle Morphology Using Amira
Published in Cells (Basel, Switzerland) (27-12-2021)“…High-resolution 3D images of organelles are of paramount importance in cellular biology. Although light microscopy and transmission electron microscopy (TEM)…”
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Systematic Transmission Electron Microscopy‐Based Identification and 3D Reconstruction of Cellular Degradation Machinery
Published in Advanced biology (01-06-2023)“…Various intracellular degradation organelles, including autophagosomes, lysosomes, and endosomes, work in tandem to perform autophagy, which is crucial for…”
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Identification of MAGEC2/CT10 as a High Calcium-Inducible Gene in Triple-Negative Breast Cancer
Published in Frontiers in endocrinology (Lausanne) (10-03-2022)“…The expression of the melanoma/cancer-testis antigen MAGEC2/CT10 is restricted to germline cells, but like most cancer-testis antigens, it is frequently…”
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Diverse Roles of Annexin A6 in Triple-Negative Breast Cancer Diagnosis, Prognosis and EGFR-Targeted Therapies
Published in Cells (Basel, Switzerland) (07-08-2020)“…The calcium (Ca )-dependent membrane-binding Annexin A6 (AnxA6), is a multifunctional, predominantly intracellular scaffolding protein, now known to play…”
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A review of undergraduate research programs aimed at underrepresented students
Published in STAR protocols (21-06-2024)“…It is well-understood that the science, technology, engineering, and mathematics (STEM) fields have unique challenges that discourage recruiting and retaining…”
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Using mass spectrometry imaging to visualize age-related subcellular disruption
Published in Frontiers in molecular biosciences (08-03-2023)“…Metabolic homeostasis balances the production and consumption of energetic molecules to maintain active, healthy cells. Cellular stress, which disrupts…”
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A pilot study on our non-traditional, varied writing accountability group for historically excluded and underrepresented persons in STEMM
Published in Heliyon (01-12-2023)“…Underrepresented faculty have higher burnout rates and lower grant attainment rates when compared with their non-minority counterparts. Many in science,…”
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Project Strengthen: An STEMM-focused career development workshop to prepare underrepresented minority students for graduate school
Published in iScience (20-10-2023)“…Maximizing Access to Research Careers (MARC) programs are aimed to increase diversity in science, technology, engineering, math, and medicine (STEMM) fields…”
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SOX6 expression and aneurysms of the thoracic and abdominal aorta
Published in iScience (20-09-2024)“…Abdominal and thoracic aortic aneurysms (AAAs, TAAs) remain a major cause of deaths worldwide, in part due to the lack of reliable prognostic markers or early…”
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Correction: Garza-Lopez et al. Protocols for Generating Surfaces and Measuring 3D Organelle Morphology Using Amira. Cells 2022, 11 , 65
Published in Cells (Basel, Switzerland) (10-05-2023)“…In the original publication [...]…”
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Cardiovascular hemodynamics in mice with tumor necrosis factor receptor-associated factor 2 mediated cytoprotection in the heart
Published in Frontiers in cardiovascular medicine (09-05-2023)“…Many studies in mice have demonstrated that cardiac-specific innate immune signaling pathways can be reprogrammed to modulate inflammation in response to…”
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β2ARs: double edge sword in heart function
Published in Trends in molecular medicine (01-06-2023)“…Deng and colleagues highlight the importance of understanding the divergent roles of β2-adrenoceptor (β2AR) in high-fat diet-induced heart failure. β2AR…”
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Lenacapavir (Sunlenca®) for the treatment of HIV-1
Published in Trends in pharmacological sciences (Regular ed.) (01-08-2023)Get full text
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Salt Sensitivity of Blood Pressure
Published in Circulation research (10-05-2024)“…The year 2024 marks the centennial of the initiation of the American Heart Association. Over the past 100 years, the American Heart Association has led…”
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