Search Results - "Beasley, David W"
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Persistent Infection with West Nile Virus Years after Initial Infection
Published in The Journal of infectious diseases (01-01-2010)“…West Nile virus (WNV) RNA was demonstrated in 5 (20%) of 25 urine samples collected from convalescent patients 573–2452 days (1.6–6.7 years) after WNV…”
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Utilization of an Eilat Virus-Based Chimera for Serological Detection of Chikungunya Infection
Published in PLoS neglected tropical diseases (01-10-2015)“…In December of 2013, chikungunya virus (CHIKV), an alphavirus in the family Togaviridae, was introduced to the island of Saint Martin in the Caribbean,…”
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Comparison of Routes of Administration, Frequency, and Duration of Favipiravir Treatment in Mouse and Guinea Pig Models of Ebola Virus Disease
Published in Viruses (01-07-2024)“…Favipiravir is a ribonucleoside analogue that has been explored as a therapeutic for the treatment of Ebola Virus Disease (EVD). Promising data from rodent…”
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Enhancement of protein expression by alphavirus replicons by designing self-replicating subgenomic RNAs
Published in Proceedings of the National Academy of Sciences - PNAS (22-07-2014)“…Since the development of infectious cDNA clones of viral RNA genomes and the means of delivery of the in vitro-synthesized RNA into cells, alphaviruses have…”
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Envelope Protein Glycosylation Status Influences Mouse Neuroinvasion Phenotype of Genetic Lineage 1 West Nile Virus Strains
Published in Journal of Virology (01-07-2005)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Status of research and development of vaccines for chikungunya
Published in Vaccine (03-06-2016)“…Highlights • Chikungunya virus caused large epidemics of arthritogenic disease around the world since 2005. • A substantial disease burden exists due to…”
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Baseline mapping of Oropouche virology, epidemiology, therapeutics, and vaccine research and development
Published in npj vaccines (17-03-2022)“…Oropouche virus (OROV) is an arthropod-borne orthobunyavirus found in South America and causes Oropouche fever, a febrile infection similar to dengue. It is…”
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New international guidance on quality, safety and efficacy of DNA vaccines
Published in npj vaccines (18-06-2020)Get full text
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Supramolecular peptide hydrogel adjuvanted subunit vaccine elicits protective antibody responses against West Nile virus
Published in Vaccine (04-11-2016)“…Abstract A crucial issue in vaccine development is to balance safety with immunogenicity. The low immunogenicity of most subunit antigens warrants a search for…”
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Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development
Published in npj vaccines (20-03-2018)“…Lassa fever (LF) is a zoonotic disease associated with acute and potentially fatal hemorrhagic illness caused by the Lassa virus (LASV), a member of the family…”
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Natural History of Marburg Virus Infection to Support Medical Countermeasure Development
Published in Viruses (01-10-2022)“…The Biomedical Advanced Research and Development Authority, part of the Administration for Strategic Preparedness and Response within the U.S. Department of…”
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Baseline mapping of severe fever with thrombocytopenia syndrome virology, epidemiology and vaccine research and development
Published in npj vaccines (17-12-2020)“…Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly emergent tick-borne bunyavirus first discovered in 2009 in China. SFTSV is a growing…”
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Vaccine value profile for Chikungunya
Published in Vaccine (25-07-2024)“…Chikungunya virus (CHIKV) a mosquito-borne alphavirus is the causative agent of Chikungunya (CHIK), a disease with low mortality but high acute and chronic…”
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Resurgence of West Nile neurologic disease in the United States in 2012: What happened? What needs to be done?
Published in Antiviral research (01-07-2013)“…•In 2012, West Nile virus disease was at the highest level in a decade.•Precise locations and intensity of WNV outbreaks remain difficult to predict.•Large…”
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Defining a correlate of protection for chikungunya virus vaccines
Published in Vaccine (28-11-2019)“…•Chikungunya fever is a arboviral disease of global significance.•Candidate vaccines to prevent chikungunya are being developed.•Clinical efficacy trials for…”
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First vaccine approval under the FDA Animal Rule
Published in npj vaccines (25-08-2016)“…The US Food and Drug Administration’s Animal Rule was established to facilitate licensure of new products for life-threatening conditions when traditional…”
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Development and characterization of non-glycosylated E and NS1 mutant viruses as a potential candidate vaccine for West Nile virus
Published in Vaccine (22-01-2010)“…Abstract West Nile virus is an arthropod-borne flavivirus that has caused substantial morbidity and mortality to animals as well as humans since its…”
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Development of Resistance to Passive Therapy with a Potently Neutralizing Humanized Monoclonal Antibody against West Nile Virus
Published in The Journal of infectious diseases (15-07-2009)“…Previous studies have established the therapeutic efficacy of humanized E16 (hE16) monoclonal antibody against West Nile virus in animals. Here, we assess the…”
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Origin and Evolution of Japanese Encephalitis Virus in Southeast Asia
Published in Journal of Virology (01-03-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cross-neutralisation of viruses of the tick-borne encephalitis complex following tick-borne encephalitis vaccination and/or infection
Published in npj vaccines (13-03-2017)“…The tick-borne encephalitis complex contains a number of flaviviruses that share close genetic homology, and are responsible for significant human morbidity…”
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