Search Results - "Bearss, Jeremy J"

Smallpox lesion characterization in placebo-treated and tecovirimat-treated macaques using traditional and novel methods by Bell, Todd M, Facemire, Paul, Bearss, Jeremy J, Raymond, Jo Lynne, Chapman, Jennifer, Zeng, Xiankun, Shamblin, Joshua D, Williams, Janice A, Grosenbach, Douglas W, Hruby, Dennis E, Damon, Inger K, Goff, Arthur J, Mucker, Eric M

“…Smallpox was the most rampant infectious disease killer of the 20th century, yet much remains unknown about the pathogenesis of the variola virus. Using…”
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Immune-Mediated Systemic Vasculitis as the Proposed Cause of Sudden-Onset Sensorineural Hearing Loss following Lassa Virus Exposure in Cynomolgus Macaques by Cashman, Kathleen A, Wilkinson, Eric R, Zeng, Xiankun, Cardile, Anthony P, Facemire, Paul R, Bell, Todd M, Bearss, Jeremy J, Shaia, Carl I, Schmaljohn, Connie S

“…Lassa virus (LASV) causes a severe, often fatal hemorrhagic disease in regions in Africa where the disease is endemic, and approximately 30% of patients…”
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Characterization of Burkholderia pseudomallei Strains Using a Murine Intraperitoneal Infection Model and In Vitro Macrophage Assays by Welkos, Susan L, Klimko, Christopher P, Kern, Steven J, Bearss, Jeremy J, Bozue, Joel A, Bernhards, Robert C, Trevino, Sylvia R, Waag, David M, Amemiya, Kei, Worsham, Patricia L, Cote, Christopher K

“…Burkholderia pseudomallei, the etiologic agent of melioidosis, is a gram-negative facultative intracellular bacterium. This bacterium is endemic in Southeast…”
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Characterization of pathogenesis of and immune response to Burkholderia pseudomallei K96243 using both inhalational and intraperitoneal infection models in BALB/c and C57BL/6 mice by Bearss, Jeremy J, Hunter, Melissa, Dankmeyer, Jennifer L, Fritts, Kristen A, Klimko, Christopher P, Weaver, Chris H, Shoe, Jennifer L, Quirk, Avery V, Toothman, Ronald G, Webster, Wendy M, Fetterer, David P, Bozue, Joel A, Worsham, Patricia L, Welkos, Susan L, Amemiya, Kei, Cote, Christopher K

“…Burkholderia pseudomallei, the etiologic agent of melioidosis, is a Gram negative bacterium designated as a Tier 1 threat. This bacterium is known to be…”
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A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever by Cashman, Kathleen A., Wilkinson, Eric R., Shaia, Carl I., Facemire, Paul R., Bell, Todd M., Bearss, Jeremy J., Shamblin, Joshua D., Wollen, Suzanne E., Broderick, Kate E., Sardesai, Niranjan Y., Schmaljohn, Connie S.

“…Lassa virus (LASV) is an ambisense RNA virus in the Arenaviridae family and is the etiological agent of Lassa fever, a severe hemorrhagic disease endemic to…”
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Identification and pathological characterization of persistent asymptomatic Ebola virus infection in rhesus monkeys by Zeng, Xiankun, Blancett, Candace D., Koistinen, Keith A., Schellhase, Christopher W., Bearss, Jeremy J., Radoshitzky, Sheli R., Honnold, Shelley P., Chance, Taylor B., Warren, Travis K., Froude, Jeffrey W., Cashman, Kathleen A., Dye, John M., Bavari, Sina, Palacios, Gustavo, Kuhn, Jens H., Sun, Mei G.

“…Ebola virus (EBOV) persistence in asymptomatic humans and Ebola virus disease (EVD) sequelae have emerged as significant public health concerns since the…”
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Dysregulation of TNF-α and IFN-γ expression is a common host immune response in a chronically infected mouse model of melioidosis when comparing multiple human strains of Burkholderia pseudomallei by Amemiya, Kei, Dankmeyer, Jennifer L, Bearss, Jeremy J, Zeng, Xiankun, Stonier, Spencer W, Soffler, Carl, Cote, Christopher K, Welkos, Susan L, Fetterer, David P, Chance, Taylor B, Trevino, Sylvia R, Worsham, Patricia L, Waag, David M

“…Melioidosis is endemic in Southeast Asia and Northern Australia and is caused by the Gram-negative, facultative intracellular pathogen Burkholderia…”
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Ebola Virus Causes Intestinal Tract Architectural Disruption and Bacterial Invasion in Non-Human Primates by Reisler, Ronald B, Zeng, Xiankun, Schellhase, Christopher W, Bearss, Jeremy J, Warren, Travis K, Trefry, John C, Christopher, George W, Kortepeter, Mark G, Bavari, Sina, Cardile, Anthony P

“…In the 2014⁻2016 West Africa Ebola Virus (EBOV) outbreak, there was a significant concern raised about the potential for secondary bacterial infection…”
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DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs by Cashman, Kathleen A., Wilkinson, Eric R., Wollen, Suzanne E., Shamblin, Joshua D., Zelko, Justine M., Bearss, Jeremy J., Zeng, Xiankun, Broderick, Kate E., Schmaljohn, Connie S.

“…We previously developed optimized DNA vaccines against both Lassa fever and Ebola hemorrhagic fever viruses and demonstrated that they were protective…”
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Ebola Virus Infections in Nonhuman Primates Are Temporally Influenced by Glycoprotein Poly-U Editing Site Populations in the Exposure Material by Trefry, John C, Wollen, Suzanne E, Nasar, Farooq, Shamblin, Joshua D, Kern, Steven J, Bearss, Jeremy J, Jefferson, Michelle A, Chance, Taylor B, Kugelman, Jeffery R, Ladner, Jason T, Honko, Anna N, Kobs, Dean J, Wending, Morgan Q S, Sabourin, Carol L, Pratt, William D, Palacios, Gustavo F, Pitt, M Louise M

“…Recent experimentation with the variants of the Ebola virus that differ in the glycoprotein's poly-uridine site, which dictates the form of glycoprotein…”
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Laser Scanning Confocal Microscopy Was Used to Validate the Presence of Burkholderia Pseudomallei or B. Mallei in Formalin-Fixed Paraffin Embedded Tissues by Amemiya, Kei, Zeng, Xiankun, Bearss, Jeremy J, Cote, Christopher K, Soffler, Carl, Bernhards, Robert C, Dankmeyer, Jennifer L, Ribot, Wilson J, Trevino, Sylvia R, Welkos, Susan L, Worsham, Patricia L, Waag, David M

“…and are Gram-negative, facultative intracellular bacteria that cause melioidosis and glanders, respectively. Currently, there are no vaccines for these two…”
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Persistent Marburg Virus Infection in the Testes of Nonhuman Primate Survivors by Coffin, Kayla M., Liu, Jun, Warren, Travis K., Blancett, Candace D., Kuehl, Kathleen A., Nichols, Donald K., Bearss, Jeremy J., Schellhase, Christopher W., Retterer, Cary J., Weidner, Jessica M., Radoshitzky, Sheli R., Brannan, Jennifer M., Cardile, Anthony P., Dye, John M., Palacios, Gustavo, Sun, Mei G., Kuhn, Jens H., Bavari, Sina, Zeng, Xiankun

“…Sexual transmission of filoviruses was first reported in 1968 after an outbreak of Marburg virus (MARV) disease and recently caused flare-ups of Ebola virus…”
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Intensive Care Unit–Like Care of Nonhuman Primates with Ebola Virus Disease by Blair, Paul W, Kortepeter, Mark G, Downey, Lydia G, Madar, Cristian S, Downs, Isaac L, Martins, Karen A, Rossi, Franco, Williams, Janice A, Madar, Annie, Schellhase, Christopher W, Bearss, Jeremy J, Zeng, Xiankun, Bavari, Sina, Soloveva, Veronica, Wells, Jay B, Stuthman, Kelly S, Garza, Nicole L, Vantongeren, Sean A, Donnelly, Ginger C, Steffens, Jesse, Kalapaca, Jennifer, Wiseman, Perry, Henry, Joseph, Marko, Shannon, Chappell, Mark, Lugo-Roman, Luis, Ramos-Rivera, Elliot, Hofer, Christian, Blue, Eugene, Moore, Joshua, Fiallos, Jimmy, Wetzel, Darrel, Pratt, William D, Unangst, Tami, Miller, Adele, Sola, James J, Reisler, Ronald B, Cardile, Anthony P

“…Abstract Background Ebola virus disease (EVD) supportive care strategies are largely guided by retrospective observational research. This study investigated…”
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Acute Exposure to Methylmercury Causes Ca2+ Dysregulation and Neuronal Death in Rat Cerebellar Granule Cells through an M3 Muscarinic Receptor-Linked Pathway by Limke, Tobi L., Bearss, Jeremy J., Atchison, William D.

“…Acute exposure to low concentrations of methylmercury (MeHg) causes a severe loss of intracellular calcium (\batchmode…”
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Interposition grafts for rectovaginal fistula repair in the New Zealand white rabbit by Aungst, Matthew J., Bearss, Jeremy J., Lewis, Bridget S., Fischer, John R., Bonhage, Michael R., Wright, Johnnie

“…Introduction and hypothesis The objective was to use an animal model to study different types of interposition grafts for rectovaginal fistula repair. Methods…”
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Smallpox lesion characterization in placebo-treated and tecovirimat-treated macaques using traditional and novel methods by Todd M. Bell, Paul Facemire, Jeremy J. Bearss, Jo Lynne Raymond, Jennifer Chapman, Xiankun Zeng, Joshua D. Shamblin, Janice A. Williams, Douglas W. Grosenbach, Dennis E. Hruby, Inger K. Damon, Arthur J. Goff, Eric M. Mucker

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Dysregulation of TNF-[alpha] and IFN-[gamma] expression is a common host immune response in a chronically infected mouse model of melioidosis when comparing multiple human strains of Burkholderia pseudomallei by Amemiya, Kei, Dankmeyer, Jennifer L, Bearss, Jeremy J, Zeng, Xiankun, Stonier, Spencer W, Soffler, Carl, Cote, Christopher K, Welkos, Susan L, Fetterer, David P, Chance, Taylor B, Trevino, Sylvia R, Worsham, Patricia L, Waag, David M

“…Melioidosis is endemic in Southeast Asia and Northern Australia and is caused by the Gram-negative, facultative intracellular pathogen Burkholderia…”
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Laser scanning confocal microscopy was used to validate the presence of 'Burkholderia pseudomallei' or 'B. mallei' in formalin-fixed paraffin embedded tissues by Kei Amemiya, Xiankun Zeng, Jeremy J Bearss, Christopher K Cote, Carl Soffler, Robert C Bernhards, Jennifer L Dankmeyer, Wilson J Ribot, Sylvia R Trevino, Susan L Welkos, Patricia L Worsham, David M Waag

“…Burkholderia pseudomallei and B. mallei are Gram-negative, facultative intracellular bacteria that cause melioidosis and glanders, respectively. Currently,…”
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Characterization of Burkholderia pseudomallei Strains Using a Murine Intraperitoneal Infection Model and In Vitro Macrophage Assays: e0124667 by Welkos, Susan L, Klimko, Christopher P, Kern, Steven J, Bearss, Jeremy J, Bozue, Joel A, Bernhards, Robert C, Trevino, Sylvia R, Waag, David M, Amemiya, Kei, Worsham, Patricia L

“…Burkholderia pseudomallei, the etiologic agent of melioidosis, is a gram-negative facultative intracellular bacterium. This bacterium is endemic in Southeast…”
Get full text