Search Results - "Beare, D. M"
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Replication timing of the human genome
Published in Human molecular genetics (15-01-2004)“…We have developed a directly quantitative method utilizing genomic clone DNA microarrays to assess the replication timing of sequences during the S phase of…”
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A first-generation linkage disequilibrium map of human chromosome 22
Published in Nature (London) (01-08-2002)“…DNA sequence variants in specific genes or regions of the human genome are responsible for a variety of phenotypes such as disease risk or variable drug…”
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Lack of evidence for an association between the frequency of mutants or translocations in circulating lymphocytes and exposure to radon gas in the home
Published in Radiation research (1996)“…Radon measurements in the living room and main bedroom of 41 houses in the town of Street, Somerset, England have been made. Exposure levels, weighted using…”
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Comparative human cellular radiosensitivity: III. Gamma-radiation survival of cultured skin fibroblasts and resting T-lymphocytes from the peripheral blood of the same individual
Published in International journal of radiation biology (1991)“…Skin and blood samples were obtained from 34 donors, for whom there was no indication of abnormal radiosensitivity. From these, in 33 cases both fibroblast and…”
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Reevaluating human gene annotation: a second-generation analysis of chromosome 22
Published in Genome research (01-01-2003)“…We report a second-generation gene annotation of human chromosome 22. Using expressed sequence databases, comparative sequence analysis, and experimental…”
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Correlated mutagenesis of bcl2 and hprt loci in blood lymphocytes
Published in Environmental and molecular mutagenesis (1997)“…In vivo measurement of human somatic mutations may be a valuable biodosimeter of exposure to carcinogens and of cancer risk. We have surveyed translocations of…”
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Biomonitoring of possible human exposure to environmental genotoxic chemicals: Lessons from a study following the wreck of the oil tanker Braer
Published in Environmental and molecular mutagenesis (1997)“…In January 1993 the oil tanker Braer ran aground in the Shetland Islands, Scotland. Approximately 80,000 tons of crude oil were released. Exceptionally high…”
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Comparative human cellular radiosensitivity: IV. The increased sensitivity of human neonatal cord blood lymphocytes to gamma-irradiation compared with lymphocytes from children and adults
Published in International journal of radiation biology (1991)“…We have compared the gamma-irradiation survival of G0 peripheral blood lymphocytes from 18 neonatal cord blood samples in a cloning assay with results from 21…”
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The DNA sequence and analysis of human chromosome 6
Published in Nature (23-10-2003)“…Chromosome 6 is a metacentric chromosome that constitutes about 6% of the human genome. The finished sequence comprises 166,880,988 base pairs, representing…”
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The DNA sequence of human chromosome 22
Published in Nature (London) (02-12-1999)“…Knowledge of the complete genomic DNA sequence of an organism allows a systematic approach to defining its genetic components. The genomic sequence provides…”
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The DNA sequence and analysis of human chromosome 13
Published in Nature (01-04-2004)“…Chromosome 13 is the largest acrocentric human chromosome. It carries genes involved in cancer including the breast cancer type 2 (BRCA2) and retinoblastoma…”
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Conservation compendium Part 10: Corrosion of steel frames behind masonry elevations - assessment and treatment
Published in Structural engineer (London, England : 1988) (01-09-2015)“…This article continues from the previous instalment in the series, and aims to guide engineers in assessing the extent of corrosion of steel frames and in…”
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The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X
Published in Nature (London) (15-02-2001)“…We constructed maps for eight chromosomes (1, 6, 9, 10, 13, 20, X and (previously) 22), representing one-third of the genome, by building landmark maps,…”
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A full-coverage, high-resolution human chromosome 22 genomic microarray for clinical and research applications
Published in Human molecular genetics (01-12-2002)“…We have constructed the first comprehensive microarray representing a human chromosome for analysis of DNA copy number variation. This chromosome 22 array…”
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Replication Timing of Human Chromosome 6
Published in Cell cycle (Georgetown, Tex.) (01-01-2005)“…Genomic microarrays have been used to assess DNA replication timing in a variety of eukaryotic organisms1-3. A replication timing map of the human genome has…”
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The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X : The human genome
Published in Nature (London) (2001)Get full text
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Replication timing of the human genome
Published in Human molecular genetics (01-03-2004)Get full text
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A genome annotation-driven approach to cloning the human ORFeome
Published in Genome biology (01-01-2004)“…We have developed a systematic approach to generating cDNA clones containing full-length open reading frames (ORFs), exploiting knowledge of gene structure…”
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Conservation compendium. Part 9: Corrosion of steel frames behind masonry elevations – introduction
Published in Structural engineer (London, England : 1988) (01-08-2015)“…This article is the first of two which will discuss the problem of corrosion of steel frames behind masonry elevations. It aims to provide an introduction to…”
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