Search Results - "Beare, C M"

Identification of a P-Glycoprotein-Deficient Subpopulation in the CF-1 Mouse Strain Using a Restriction Fragment Length Polymorphism by Umbenhauer, Diane R., Lankas, George R., Pippert, Todd R., Wise, L.David, Cartwright, Mark E., Hall, Steven J., Beare, Carolann M.

“…There is a subpopulation of the CF-1 mouse strain that is very sensitive to the neurotoxicity induced by the avermectins, a class of natural products widely…”
Get full text

Plasmid DNA vaccines: assay for integration into host genomic DNA by Ledwith, B J, Manam, S, Troilo, P J, Barnum, A B, Pauley, C J, Griffiths, 2nd, T G, Harper, L B, Schock, H B, Zhang, H, Faris, J E, Way, P A, Beare, C M, Bagdon, W J, Nichols, W W

“…The primary safety concern for DNA vaccines is their potential to integrate into host cellular DNA. We describe a sensitive and quantitative assay for…”
Get more information

Cardiac electrophysiologic and antiarrhythmic actions of two long-acting spirobenzopyran piperidine class III agents, L-702,958 and L-706,000 [MK-499] by Lynch, Jr, J J, Wallace, A A, Stupienski, 3rd, R F, Baskin, E P, Beare, C M, Appleby, S D, Salata, J J, Jurkiewicz, N K, Sanguinetti, M C, Stein, R B

“…The cardiac electrophysiologic and antiarrhythmic actions of two Class III ketone- and alcohol-containing spirobenzopyran piperidine analogs, L-702,958 and…”
Get more information

Plasmid DNA vaccines: investigation of integration into host cellular DNA following intramuscular injection in mice by Ledwith, B J, Manam, S, Troilo, P J, Barnum, A B, Pauley, C J, Griffiths , 2nd, T G, Harper, L B, Beare, C M, Bagdon, W J, Nichols, W W

“…The primary safety concern for DNA vaccines is their potential to integrate into the host cell genome. We describe an integration assay based on purification…”
Get more information

Plasmid DNA vaccines: tissue distribution and effects of DNA sequence, adjuvants and delivery method on integration into host DNA by Manam, S, Ledwith, B J, Barnum, A B, Troilo, P J, Pauley, C J, Harper, L B, Griffiths , 2nd, T G, Niu, Z, Denisova, L, Follmer, T T, Pacchione, S J, Wang, Z, Beare, C M, Bagdon, W J, Nichols, W W

“…A variety of factors could affect the frequency of integration of plasmid DNA vaccines into host cellular DNA, including DNA sequences within the plasmid, the…”
Get more information

Effect of an Environmental Enrichment Device on Individually Caged Rabbits in a Safety Assessment Facility by Johnson, Colena A, Pallozzi, Wendi A, Geiger, Leann, Szumiloski, John L, Castiglia, Lynn, Dahl, Noelle P, Destefano, James A, Pratt, Stacy J, Hall, Steven J, Beare, Carolann M, Gallagher, Michael, Klein, Hilton J

“…The primary enclosure of a laboratory animal's environment should encourage species-typical behavior and enhancement of the animal's well-being, as indicated…”
Get full text