Search Results - "Beard, K S"
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Disruption of Transplant Tolerance by an “Incognito” Form of CD8 T Cell–Dependent Memory
Published in American journal of transplantation (01-07-2017)“…Several approaches successfully achieve allograft tolerance in preclinical models but are challenging to translate into clinical practice. Many clinically…”
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Ligation of Major Histocompatibility Complex Class II Molecules Mediates Apoptotic Cell Death in Resting B Lymphocytes
Published in Proceedings of the National Academy of Sciences - PNAS (15-11-1993)“…Class II major histocompatibility complexencoded molecules expressed on the surface of primed B lymphocytes function as restriction elements for presentation…”
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Resistance of spontaneously diabetic Ins2(akita) mice to allograft tolerance induced by anti-CD154 therapy
Published in Transplantation proceedings (01-07-2014)“…Despite ongoing advances in the clinical islet transplant field, progressive decline in graft function continues to reduce the long-term success of islet…”
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Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells
Published in Cancer research (Chicago, Ill.) (01-02-2003)“…Colorectal cancer is the second leading cause of cancer death in the United States. Nonsteroidal anti-inflammatory drugs including sulindac are promising…”
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Functional analysis of the antigen binding region of an MHC class II molecule
Published in Molecular immunology (01-04-1993)“…The MHC class II molecules bind antigenic peptides and present them to T cells. Their ability to carry out these functions depends, in a critical way, on the…”
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Immunoglobulin M and immunoglobulin G responses in BALB/c mice to conjugated outer membrane extracts of four Salmonella serotypes
Published in Infection and Immunity (01-09-1985)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immunologic memory responses induced in BALB/c mice by cross-linked outer membrane extracts of four Salmonella serotypes
Published in American journal of veterinary research (01-08-1987)“…Outer membrane proteins (OMP), extracted from Salmonella enteritidis, S anatum, S typhimurium, and S infantis, were cross-linked to form a large immunogen…”
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Sulindac metabolites induce caspase- and proteasome-dependent degradation of β-catenin protein in human colon cancer cells
Published in Molecular cancer therapeutics (01-09-2003)“…Colorectal cancer (CRC) is the second leading cause of cancer death in the USA. Accumulation of β-catenin protein is nearly ubiquitous in colon adenomas and…”
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Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites
Published in Cancer research (Chicago, Ill.) (15-11-2004)“…Nonsteroidal anti-inflammatory drugs (NSAIDs) including sulindac have shown potent chemopreventive and tumor regressive effects against colorectal cancer, the…”
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Sulindac independently modulates extracellular signal–regulated kinase 1/2 and cyclic GMP–dependent protein kinase signaling pathways
Published in Molecular cancer therapeutics (01-03-2006)“…Colorectal cancer is the second leading cause of cancer mortality in the United States. Substantial human and animal data support the ability of nonsteroidal…”
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