Search Results - "Bear, David G"

A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting by Lee, Luke P, Chen, Fanqing Frank, Liu, Gang L, Yin, Yadong, Kunchakarra, Siri, Mukherjee, Bipasha, Gerion, Daniele, Jett, Stephen D, Bear, David G, Gray, Joe W, Alivisatos, A. Paul

“…Interactions between nucleic acids and proteins are essential to genetic information processing. The detection of size changes in nucleic acids is the key to…”
Get full text

DNA Looping by Ku and the DNA-Dependent Protein Kinase by Cary, Robert B., Peterson, Scott R., Wang, Jinting, Bear, David G., Bradbury, E. Morton, Chen, David J.

“…The DNA-dependent protein kinase (DNA-PK) is required for DNA double-strand break (DSB) repair and immunoglobulin gene rearrangement and may play a role in the…”
Get full text

Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cells by Melendez, Karla, Wallen, Erik S., Edwards, Bruce S., Mobarak, Charlotte D., Bear, David G., Moseley, Pope L.

“…Heat shock proteins (HSPs), which are important for a number of different intracellular functions, are occasionally found on the surface of cells. The function…”
Get full text

Cationic Phenylene Ethynylene Polymers and Oligomers Exhibit Efficient Antiviral Activity by Wang, Ying, Canady, Taylor D, Zhou, Zhijun, Tang, Yanli, Price, Dominique N, Bear, David G, Chi, Eva Y, Schanze, Kirk S, Whitten, David G

“…The antiviral activities of poly(phenylene ethynylene) (PPE)-based cationic conjugated polyelectrolytes (CPE) and oligo-phenylene ethynylenes (OPE) were…”
Get full text

Student peer assessment in evidence-based medicine (EBM) searching skills training: an experiment by ELDREDGE, Jonathan D, BEAR, David G, WAYNE, Sharon J, PEREA, Paul P

“…Student peer assessment (SPA) has been used intermittently in medical education for more than four decades, particularly in connection with skills training…”
Get full text

Nuclear poly(A)-binding protein PABPN1 is associated with RNA polymerase II during transcription and accompanies the released transcript to the nuclear pore by Bear, David G, Fomproix, Nathalie, Soop, Teresa, Björkroth, Birgitta, Masich, Sergej, Daneholt, Bertil

“…The nuclear poly(A)-binding protein, PABPN1, has been previously shown to regulate mRNA poly(A) tail length and to interact with selected proteins involved in…”
Get full text

Oculopharyngeal Muscular Dystrophy in Hispanic New Mexicans by Becher, Mark W, Morrison, Leslie, Davis, Larry E, Maki, Wusi C, King, Molly K, Bicknell, Joseph M, Reinert, Brian L, Bartolo, Claire, Bear, David G

“…CONTEXT Oculopharyngeal muscular dystrophy (OPMD) is a rare myopathy caused by polyalanine triplet repeat expansion in the gene for poly(A) binding protein 2…”
Get full text

Intranuclear inclusions in oculopharyngeal muscular dystrophy contain poly(A) binding protein 2 by Becher, Mark W., Kotzuk, Joyce A., Davis, Larry E., Bear, David G.

“…Intranuclear inclusions are one of the ultrastructural hallmarks of oculopharyngeal muscular dystrophy (OPMD), a disorder caused by small polyalanine (GCG)…”
Get full text

Protein-Nucleic Acid Interactions in Transcription: A Molecular Analysis by von Hippel, Peter H, Bear, David G, Morgan, William D, McSwiggen, James A

“…The authors review what is currently known about the transcription process, focusing on the sequence of events in which RNA polymerase is involved as it moves…”
Get full text

Electron Microscopy with a Digital Flavor by Bear, David G

Get full text

Snapshot Blotting: Transfer of Nucleic Acids and Nucleoprotein Complexes from Electrophoresis Gels to Grids for Electron Microscopy by Jett, Stephen D., Bear, David G.

“…We present a technique, "snapshot blotting," for the electrophoretic transfer of nucleic acids and nucleoprotein complexes in gel electrophoresis bands onto…”
Get full text

3'-End formation at the phage .lambda. tR1 .rho.-dependent transcription termination site by Roberts, Elizabeth A, Eisenbraun, Theresa L, Andrews, Christopher L, Bear, David G

“…The rho-dependent transcription terminator tR1 of bacteriophage lambda stops RNA synthesis downstream of the major rightward promoter, PR, shortly after the…”
Get full text

The nuclear poly(A) binding protein, PABP2, forms an oligomeric particle covering the length of the poly(A) tail by Keller, Rebecca W., Kühn, Uwe, Aragón, Mateo, Bornikova, Larissa, Wahle, Elmar, Bear, David G.

“…The mammalian nuclear poly(A) binding protein, PABP2, controls the length of the newly synthesized poly(A) tail on messenger RNAs. To gain a better…”
Get full text

TRAP, the trp RNA-Binding Attenuation Protein of Bacillus subtilis, is a Toroid-Shaped Molecule that Binds Transcripts Containing GAG or UAG Repeats Separated by Two Nucleotides by Babitzke, Paul, Bear, David G., Yanofsky, Charles

“…The trp RNA-binding attenuation protein of Bacillus subtilis, TRAP, regulates both transcription and translation by binding to specific transcript sequences…”
Get full text

Stable DNA Heteroduplex Formation Catalyzed by the Escherichia coli RecA Protein in the Absence of ATP Hydrolysis by Menetski, Joseph P., Bear, David G., Kowalczykowski, Stephen C.

“…A question remaining to be answered about RecA protein function concerns the role of ATP hydrolysis during the DNA-strand-exchange reaction. In this paper we…”
Get full text

Intramolecular synapsis of duplex DNA by vaccinia topoisomerase by Shuman, Stewart, Bear, David G., Sekiguchi, JoAnn

“…Complexes formed by vaccinia topoisomerase I on plasmid DNA were visualized by electron microscopy. The enzyme formed intramolecular loop structures in which…”
Get full text

TRAP, the trp RNA-binding attenuation protein of Bacillus subtilis, is a toroid-shaped molecule that binds transcripts containing GAG or UAG by Babitzke, Paul, Bear, David G, Yanofsky, Charles

“…The optimum binding site for the trp RNA-binding attenuation protein of Bacillus subtilis, TRAP, was determined and the transmission EM was used to image the…”
Get full text

Escherichia Coli Helicase II (UvrD) Protein Initiates DNA Unwinding at Nicks and Blunt Ends by Runyon, Gregory T., Bear, David G., Lohman, Timothy M.

“…The Escherichia coli uvrD gene product, helicase II, is required for both methyl-directed mismatch and uvrABC excision repair and is believed to function by…”
Get full text

Interactions of Escherichia coli transcription termination factor rho with RNA. I. Binding stoichiometries and free energies by McSwiggen, J A, Bear, D G, von Hippel, P H

“…In this paper we examine the binding of Escherichia coli transcription termination factor rho to single-stranded RNA. Random polyribonucleotide copolymers…”
Get more information

RNA sequence and secondary structure requiresments for rho-dependent transcription termination by Morgan, William, Bear, David G., Litchman, Bronwen L., von Hippel, Peter H.

“…The interaction of E. coli termination factor rho with the nascent RNA transcript appears to be a central feature of the rho-dependent transcription…”
Get full text