Search Results - "Bear, D. Michael"
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Roflumilast 0.3% Cream: a Phosphodiesterase 4 Inhibitor for the Treatment of Chronic Plaque Psoriasis
Published in American journal of therapeutics (01-11-2023)“…BACKGROUNDPlaque psoriasis is a chronic dermatologic autoimmune disease that affects adults and children. Roflumilast 0.3% cream is currently the only topical…”
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Vascular smooth muscle ROCK1 contributes to hypoxia-induced pulmonary hypertension development in mice
Published in Biochemical and biophysical research communications (14-05-2022)“…Rho kinase (ROCK) is implicated in the development of pulmonary arterial hypertension (PAH) in which abnormal pulmonary vascular smooth muscle (VSM)…”
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Transgender health education for pharmacy students and its effect on student knowledge and attitudes
Published in Currents in pharmacy teaching and learning (01-10-2021)“…Increased student pharmacist education on health issues and concerns of the underserved Lesbian, gay, bisexual, transgender, and queer (LGBTQ) population is…”
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Evolution of Staphylococcus aureus under vancomycin selective pressure: the role of the small-colony variant phenotype
Published in Antimicrobial agents and chemotherapy (01-02-2015)“…Staphylococcus aureus small-colony variants (SCVs) often persist despite antibiotic therapy. Against a 10(8)-CFU/ml methicillin-resistant S. aureus (MRSA)…”
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Alpha-Catulin Co-Localizes With Vimentin Intermediate Filaments and Functions in Pulmonary Vascular Endothelial Cell Migration via ROCK
Published in Journal of cellular physiology (01-04-2016)“…The ubiquitous α‐catulin acts as a scaffold for distinct signalosomes including RhoA/ROCK; however, its function is not well understood. While α‐catulin has…”
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The Lbc Rho Guanine Nucleotide Exchange Factor/α-Catulin Axis Functions in Serotonin-induced Vascular Smooth Muscle Cell Mitogenesis and RhoA/ROCK Activation
Published in The Journal of biological chemistry (22-10-2010)“…Serotonin (5-hydroxytryptamine, 5-HT) is mitogenic for several cell types including pulmonary arterial smooth muscle cells (PASMC), and is associated with the…”
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Pharmacist Counseling and the Use of Nonsteroidal Anti-Inflammatory Drugs by Older Adults
Published in The Consultant pharmacist (01-03-2017)“…To determine the impact a medication review has on the detection and use of nonsteroidal anti-inflammatory drugs (NSAIDs) by older adults compared with…”
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The Lbc Rho Guanine Nucleotide Exchange Factor/a-Catulin Axis Functions in Serotonin-induced Vascular Smooth Muscle Cell Mitogenesis and RhoA/ROCK Activation
Published in The Journal of biological chemistry (22-10-2010)“…Serotonin (5-hydroxytryptamine, 5-HT) is mitogenic for several cell types including pulmonary arterial smooth muscle cells (PASMC), and is associated with the…”
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Single Doses of Methacycline and Doxycycline for Gonorrhea: A Cooperative Study of the Frequency and Cause of Treatment Failure
Published in The Journal of infectious diseases (01-04-1973)“…Use of single oral doses of the various congeners of tetracycline has been widely recommended as an alternative to penicillin for treatment of uncomplicated…”
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